Professor, Department of Neuroscience and Physiology
Professor, Department of Psychiatry
My current research focuses on pathogenesis, treatment, and diagnosis of age-related degenerative diseases—in particular Alzheimer’s disease and, more recently, Parkinson’s disease and related synucleinopathies.
In these protein conformational disorders, a normal protein is converted to a pathological form with high beta-sheet content. The main theme of my work involves clarifying this pathological process, its consequences at the molecular and functional levels, and how best to diagnose and prevent it.
PhD from Loyola University Chicago
PhD from Loyola University Chicago
New York University , Frangione Lab
Molecular neurodegeneration. 2024 May 31; 19(1):44
Science advances. 2023 May 10; 9(19):eadf3775
EBioMedicine. 2022 Sep 10; 84:104249
Neurobiology of disease. 2021 Jan; 147:105165
EBioMedicine. 2019 Apr; 42:157-173
EBioMedicine. 2018 Sep; 35:270-278
Cell death & disease. 2024 Jul 30; 15(7):543
Nature reviews. Neurology. 2023 Dec; 19(12):715-736