At the Basu lab we study communication between synapses and circuits to understand how long-term memories are formed and how these memories from our past experiences shape ongoing sensory processing.

Our Goal

The goal of our research is to understand how sensory experiences trigger activity in functionally linked neurons to encode important features of the environment into long term memory representations and shape learnt behaviors.

Our Focus

Our research focuses on examining the dynamic interactions between the hippocampus and the entorhinal cortex in the mouse to understand the synaptic and circuit mechanisms of spatial and contextual learning. These brain functions are crucial in our ability to adapt to changing environments and alter behavior appropriately.

What We Utilize

We utilize electrophysiology, imaging and genetic manipulations in brain slices and awake behaving mice. We are particularly motivated to explore links between mnemonic and plastic circuits, associational learning and adaptive behaviors.