Marcus B. Noyes

Marcus B. Noyes, PhD

Marcus B. Noyes, PhD
Assistant Professor, Biochemistry and Molecular Pharmacology
The Institute for Systems Genetics
Alexandria Center for Life Science, West, Room 510
30 East 29th Street, New York, NY 10016
Tel Office:                   646-501-4589
Tel Lab:                    


Transcription regulation, synthetic biology, systems biology, genome editing, signal transduction


Graduate Education:            PhD in Biochemistry at the University of Massachusetts Medical School (2009)                                                       

Academic Appointments:     2009: Lewis-Sigler Fellow, Princeton University
                                          2015: Assistant Professor in Biochemistry, NYU Langone Medical Center


Cellular processes are largely controlled by the protein-DNA and protein-protein interactions that define them but only a small set of these interactions have been fully described. When one considers all the possible mutations that may influence these proteins and their potential binding partners, an inclusive analysis of all possible interactions presents a seemingly insurmountable task. Alternatively we take a “holistic” synthetic approach to define the ligand-binding specificity of common protein domains in an attempt to go beyond the relatively limited set of interactions that have evolved naturally and provide a truly predictive understanding of protein function.