Wei Dai

Wei Dai, PhD
Professor
Departments of Biochemistry and Molecular Pharmacology, and Environmental Medicine
57 Old Forge Road, Tuxedo, NY 10987
Office: 845-731-3555
Lab: 845-731-5228
Emailwei.dai@nyumc.org

KEY INTERESTS:
Cell Cycle, checkpoint control, mitosis, protein kinases, chromosomal instability

BIOGRAPHICAL DETAILS:
Graduate Education: Ph.D. at Purdue University (1988)
Postdoctoral Training: Hipple Cancer Research Center (1988-1990)
Academic Appointments: 
1992: Assistant professor
1994: Assistant Professor in Hematology/Oncology
1998: Associate professor in Hematology/Oncology
2001: Professor in Biochemistry & Pathology

Major Responsibilities:
Course Director: Environmental Carcinogenesis
Graduate Advisor
NYU Cancer Center Growth Control Program Co-leader
NIEHS Center Focus Group Co-leader

RESEARCH INTERESTS:
Extensive research in the past two decades has uncovered important surveillance mechanisms, commonly referred to as checkpoints, that regulate cell cycle progression. These checkpoints monitor specific cellular and molecular processes and block cell cycle progression until these processes are completed with high fidelity. An underlying genetic instability is required for the generation of multiple lesions that are characteristic of cancer. Genetic instability could be manifested as alterations in chromosome number (aneuploidy), as well as translocations, deletions, and insertions. Given that aneuploidy is frequently present in many types of tumor cells, the Dai laboratory is interested in identifying, and elucidating the function of, molecular components thatregulate cell cycle checkpoints and suppresschromosomal instability and tumorigenesis during cell division.

SELECTED PUBLICATIONS

LAB MEMBERS
Dazhong Xu, Research Assistant Professor
Feikun Yang, Post-doctoral Research Associate
Byeong Choi, Post-doctoral Research Associate
Yan Chen, Visiting Scientist
Yixin Yao, Graduate Student
Liyan Hu, Graduate Student
Yinhua Lu, Visiting Graduate Student
Mike Dimtsios, Graduate Student
Xianan Liu, Graduate Student