Regenerative Medicine Program Clinical Research | NYU Langone Health

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Regenerative Medicine Program Clinical Research

Physicians and researchers in the Regenerative Medicine Program at NYU Langone conduct clinical trials to help patients by developing new treatments using regenerative technologies.

Below is a partial list of clinical trials led by our faculty in collaboration with clinical partners across the institution. In 2019, our team participated in more than 100 trials in an effort to rapidly advance the field of regenerative medicine and realize the enormous potential of treatments using stem cells, engineered tissues, and other biomaterials.

For more information about our trials, email Meliza Shivbaran, program assistant, at

Study Evaluating CERAMENT G in Surgical Repair of Open Diaphyseal Tibial Fractures

In this prospective, randomized, multicenter, controlled trial, we aim to demonstrate the safety and effectiveness of CERAMENT G used in conjunction with standard-of-care treatment compared with standard-of-care treatment alone in people with open fractures of the tibial diaphysis.

See full clinical trial information.

Effects of Inflammatory Biomarker Profile on Functional Outcomes in Patients Undergoing BMAC Injections for Knee Osteoarthritis

In this study, we evaluate whether we can predict success or failure of stem cell injections for early stage knee osteoarthritis.

Application of Forward-Looking Infrared for the Identification and Evaluation of Fractures in the Acute Trauma Setting

This clinical trial evaluates a novel imaging technology to screen trauma patients for occult injuries.

Effectiveness Trial for Evaluating Intra-Articular Hyaluronan for Patellofemoral Pain Syndrome

The purpose of this study is to determine the safety and effectiveness of intra-articular hyaluronan injections for the treatment of symptomatic patellofemoral pain syndrome and determine whether this treatment can provide incremental clinical benefits over standard care.

See full clinical trial information.

Efficacy of AposTherapy in Knee Osteoarthritis

This prospective, interventional, randomized, double-arm clinical evaluation study examines the efficacy of AposTherapy® versus a control group in the short term at 6 months after treatment and in the long term at 12 months after treatment. The primary efficacy assessment is based on improved knee pain score and improved function in patients following diagnosis of knee osteoarthritis.

See full clinical trial information.

Intra-Articular Hyaluronan Knee Injections of HYMOVIS Combined with Physical Exercise Program Compared to Exercise Alone in a Relatively Young, Active Population with Patellofemoral Osteoarthritis or Tibiofemoral Osteoarthritis

This post-market, single-blind, multicenter, randomized, controlled clinical study enrolls relatively young, active subjects with patellofemoral osteoarthritis, tibiofemoral osteoarthritis, or both conditions to compare responses to treatment with two weekly injections of HYMOVIS—an intra-articular hyaluronan injection, with each injection given one week apart and combined with a physical exercise program (PEP)—with PEP alone.

Because PEP or exercise programs may be considered the first-line standard of care in osteoarthritis knee pain, particularly in younger, active patients, the hypothesis of the study is that HYMOVIS combined with a PEP program provides greater relief of pain associated with knee osteoarthritis than with use of PEP alone.

See full clinical trial information.

An Investigation of ReNu Knee Injection in Patients with Osteoarthritis

This is a prospective, randomized study evaluating the efficacy of ReNu for the treatment of Kellgren-Lawrence grade 2 or 3 osteoarthritis. Patients will be randomized into one of three groups for injection into the effected knee: group one will receive ReNu; group two will receive a hyaluronic acid injection with commonly used injection material; and group three will receive saline. After treatment, patients will be followed for up to 12 months to evaluate improvements using common pain and function subscales.

See full clinical trial information.

Effect of A2AR Agonists on Osteogenic Potential of Stem Cells

The purpose of this study is to conduct research on the stem cells of specimens that would otherwise be discarded during a plastic surgery operating procedure.

Learn more about this clinical trial.

Active clinical trials in plastic surgery include the following:

  • Hansjörg Wyss Department of Plastic Surgery Tissue Repository
  • Oncologic Safety of Autologous Fat Grafting
  • Microvascular Craniofacial Reconstruction
  • Hyperbaric Oxygen Therapy for Adverse Radiation Side Effects
  • Outcomes of Immediate Breast Reconstruction After Mastectomy
  • Orthoplastic Approach to Complex Musculoskeletal Pathology