Request Biospecimen, Data, or Clinical Data Resources from the Alzheimer’s Disease Center
A major function of the Alzheimer’s Disease Center is to provide research resources to investigators at NYU Langone and affiliated or collaborating institutions. Such resources include well-diagnosed research subjects for participation in specific studies, blood and cerebrospinal fluid samples acquired from these subjects, donated brain tissue from autopsied Alzheimer’s Disease Center subjects, and clinical and biochemical data acquired from these subjects, including demographic, psychosocial, medical, psychiatric, neurological, neuropsychological, neuroradiological, biochemical, genetic, and neuropathological data.
Several factors must be considered in approving allocation to investigators. These factors include the following:
- adequate scientific quality and feasibility of the proposed study, as well as qualifications and experience of the investigators
- possible duplication, overlap, or conflict with previous, current, or planned studies by other investigators
- limited availability of specific resources, such as brain tissue or cerebrospinal fluid
- maintenance of strict subject confidentiality and adherence to rules governing the use of human subjects and tissue or DNA in accordance with that National Institutes of Health (NIH) and NYU Langone Health guidelines
Investigators must also be willing to do the following:
- limit use of the resources provided to the specific aims of the submitted study protocol
- not share the resources with any other investigators without separate Alzheimer’s Disease Center approval
- submit any resulting manuscripts or conference abstracts to the Alzheimer’s Disease Center for review and comment before submission
- acknowledge the Alzheimer’s Disease Center as the source of the resource in all resulting publications
How to Request Resources
So that the Alzheimer’s Disease Center can properly and consistently consider potential factors that might limit allocation of resources, we ask that you follow our resource allocation procedures:
- Fill out our online form and submit a written request detailing the specific resources required. This request must include a study protocol indicating the specific aims, scientific rationale, methods, procedure, and analysis of results. Investigators unknown to the Alzheimer’s Disease Center may be asked to include a CV.
- In signing this form, the investigators agree to restrict their use of the resources to the aims and procedures indicated in their protocol, and to adhere to the other conditions specified on the form.
Your request is automatically submitted to the Alzheimer’s Disease Center administrator, the relevant core leaders and/or project directors responsible for the resource, or the Alzheimer’s Disease Center director. Copies will also be provided to all members of the Alzheimer’s Disease Center executive committee. Approval by the core leaders and/or the project directors responsible for the resource, as well as the Alzheimer’s Disease Center director, is required before resource allocation. This approval must be documented on the resource utilization form submitted by the applicant. Copies of approved resource utilization forms will be provided to all members of the executive committee.
If a core leader and/or project director and the Alzheimer’s Disease Center director fail to agree, the request will be reviewed and discussed at a meeting of the Alzheimer’s Disease Center executive committee. Applicants have the right to present additional information in writing or in person at the meeting. The final, binding allocation decision will be determined by a majority vote of the full executive committee. The vote of absent members of the committee will be sought if a majority decision is not obtainable at the meeting.
For studies involving human subjects that require institutional review board (IRB) approval, resources may not be allocated until the Alzheimer’s Disease Center receives a copy of the IRB approval. IRB approval may not be obtained subsequent to the allocation decision.