Guang Yang

Guang Yang, PhD

Associate Professor, Department of Anesthesiology, Perioperative Care, and Pain Medicine

neuro-immune interactions under physiological and pathological conditions, mechanisms of anesthetic neurotoxicity in developing and aged brain

The brain is segregated from the rest of the body via the blood-brain barrier and has long been considered as an immune privileged organ. Recently, this view has shifted dramatically with increasing evidence showing a complex reciprocal relationship between the immune and nervous systems in health and disease. My laboratory studies the mechanisms by which pathological immune responses contribute to neurological disorders such as multiple sclerosis, Alzheimer's disease and chronic pain. We are also interested in the relationship between anesthetic neurotoxicity and postoperative cognitive dysfunction. The laboratory uses a combination of techniques including in vivo two-photon imaging, molecular manipulation, biochemistry and behavioral analysis to address these questions.



Academic office

560 First Avenue

Fifth Floor

New York, NY 10016

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These focus areas and their associated publications are derived from medical subject headings from PubMed.
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Associate Professor, Department of Anesthesiology, Perioperative Care, and Pain Medicine

PhD from Tsinghua University

Wang, B; Liu, Y; Huang, L; Chen, J; Li, J J; Wang, R; Kim, E; Chen, Y; Justicia, C; Sakata, K; Chen, H; Planas, A; Ostrom, R S; Li, W; Yang, G; McDonald, M P; Chen, R; Heck, D H; Liao, F-F

Molecular psychiatry. 2017 Jul; 22(7):935-935

Cichon, Joseph; Blanck, Thomas J J; Gan, Wen-Biao; Yang, Guang

Nature neuroscience. 2017 Jun 26; 20(8):1122-1132

Zhang, Qiaosheng; Manders, Toby; Tong, Ai Phuong; Yang, Runtao; Garg, Arpan; Martinez, Erik; Zhou, Haocheng; Dale, Jahrane; Goyal, Abhinav; Urien, Louise; Yang, Guang; Chen, Zhe; Wang, Jing

eLife. 2017 May 19; 6:

Garre, Juan Mauricio; Silva, Hernandez Moura; Lafaille, Juan J; Yang, Guang

Nature medicine. 2017 May 15; 23(6):714-722

Huang, Lianyan; Hayes, Scott; Yang, Guang

Neurotoxicology & teratology. 2017 Mar; 60:75-81

Garre, Juan Mauricio; Yang, Guang; Bukauskas, Feliksas F; Bennett, Michael V L

Bio-protocol. 2017 Jan 20; 7(2):

Li, Wei; Ma, Lei; Yang, Guang; Gan, Wen-Biao

Nature neuroscience. 2017 Jan 16; 20(3):427-437

Yang, Siming; Gu, Changping; Mandeville, Emiri T; Dong, Yuanlin; Esposito, Elga; Zhang, Yiying; Yang, Guang; Shen, Yuan; Fu, Xiaobing; Lo, Eng H; Xie, Zhongcong

Frontiers in immunology. 2017; 8:902-902