The brain is segregated from the rest of the body via the blood-brain barrier and has long been considered as an immune privileged organ. Recently, this view has shifted dramatically with increasing evidence showing a complex reciprocal relationship between the immune and nervous systems in health and disease. My laboratory studies the mechanisms by which pathological immune responses contribute to neurological disorders such as multiple sclerosis, Alzheimer's disease and chronic pain. We are also interested in the relationship between anesthetic neurotoxicity and postoperative cognitive dysfunction. The laboratory uses a combination of techniques including in vivo two-photon imaging, molecular manipulation, biochemistry and behavioral analysis to address these questions.
Assistant Professor, Department of Anesthesiology, Perioperative Care, and Pain Medicine
PhD from Tsinghua University
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