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Karen Maass

Karen Maass, PhD

Research Assistant Professor, Department of Medicine

Keywords
tissue-specific differentiation of pluripotent stem cells , functional engraftment in regenerative cell replacement
Summary

 

My laboratory is broadly interested in cardiac development and stem cell biology. To study cardiomyocytes in health and disease, we generate stem cell models or transgenic mice by introducing reporter genes or mutations into the DNA of pluripotent stem cells. Using these models, we optimize the properties of cardiomyocytes derived from pluripotent stem cells for their useful application in pharmacological, personalized medicine and regenerative medicine approaches. In more detail, my research interests are

1) to advance methods to specifically generate cardiomyocyte subtypes,

2) to improve the electro-mechanical maturity of in vitro differentiated cardiomyocytes, and

3) to use stem cell-derived cardiomyocytes to investigate the pathogenesis and progression of cardiovascular disease.  

Phone

212-263-4126

Fax

212-263-4129

Academic office

435 East 30th Street, Science Building

7th Floor, Room 704

NYC, NY 10016

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These focus areas and their associated publications are derived from medical subject headings from PubMed.
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Research Assistant Professor, Department of Medicine

Mahoney, Vanessa M; Mezzano, Valeria; Mirams, Gary R; Maass, Karen; Li, Zhen; Cerrone, Marina; Vasquez, Carolina; Bapat, Aneesh; Delmar, Mario; Morley, Gregory E

Scientific reports. 2016 05 31; 6:26744

Tsai, Su-Yi; Maass, Karen; Lu, Jia; Fishman, Glenn I; Chen, Shuibing; Evans, Todd

Stem cell reports. 2015 Jun 09; 4(6):1089-102

Maass, Karen; Shekhar, Akshay; Lu, Jia; Kang, Guoxin; See, Fiona; Kim, Eugene; Delgado, Camila; Shen, Steven; Cohen, Lisa; Fishman, Glenn I

Stem cells. 2015 Apr; 33(4):1102-12

Maass, K; Lu, J; See, F; D'Souza, S; Fishman, G I

Heart rhythm. 2013 Nov; 10(11):1748-1748

Lader JM; Vasquez C; Bao L; Maass K; Qu J; Kefalogianni E; Fishman G; Coetzee WA; Morley GE

American journal of physiology. Heart & circulatory physiology. 2011 Sep; 301(3):H964-74

Oxford, Eva M; Danko, Charles G; Kornreich, Bruce G; Maass, Karen; Hemsley, Shari A; Raskolnikov, Dima; Fox, Philip R; Delmar, Mario; Moise, N Sydney

Journal of veterinary cardiology. 2011 Jun; 13(2):101-13

Kozoriz, Michael G; Bechberger, John F; Bechberger, Geralyn R; Suen, Michael W H; Moreno, Alonso P; Maass, Karen; Willecke, Klaus; Naus, Christian C

Journal of neuropathology & experimental neurology. 2010 Feb; 69(2):196-206

Maass, Karen; Chase, Sharon E; Lin, Xianming; Delmar, Mario

Cardiovascular research. 2009 Dec 01; 84(3):361-7