The pre-doctoral training program includes: (a) rigorous research training in the principal investigator’s laboratory (within which they will identify, face and solve problems by developing and using critical thinking and laboratory skills, applying the hypothesis-driven scientific method of proposing models and testing them, and by deepening their knowledge of the relevant literature); (b) broad education in genome function, biochemistry, genetics, and cell biology; (c) Bioinformatics and Statistics, Nuclear Cell Biology, and Genome Integrity courses; (d) active participation in the Genome Integrity seminar series/presentation/journal club, and an annual retreat; (e) opportunities to hone grant-writing and presentation skills; (f) discussion groups and lectures focusing on issues of ethical conduct in science and career options for biology graduates; and (g) a three-tiered mentoring system consisting of a first-year faculty mentor, research advisor and thesis committee.