Knaut Lab

Embryonic development involves extensive cell and tissue movements. Cells are often born far from their final position and face the challenge of navigating through the embryo to reach their destination and assemble into organs. To accomplish this task, they have to correctly interpret guidance cues, interact with various tissues along their migratory route and communicate with each other. We are trying to understand these principles using two different models:

  • the clustering of individual neuronal precursors into a ganglion and
  • the migration of muscle and cartilage precursors into the head