Biochemical and Biomechanical Determinants of Pain in 1st MTP Joint OA

Full Title of Study

Biochemical and Biomechanical Determinants of Pain in 1st MTP Joint OA (R# 10-00790)

Purpose of Study

The purpose of this study is two-fold: 1) To see how well surgery works for great toe foot pain and arthritis, and 2) To assess if foot pain is related to the enzymes inside the great toe joint.

Basic Inclusion Criteria (requirements for being included in study)

  • Age 18 years or older
  • Loss of mobility and function of the great toe joint

Basic Exclusion Criteria (reasons for being excluded from study)

  • Inability to walk independently
  • Uncontrolled cardiovascular or neuromusculoskeletal disease
  • lower extremity surgery less than 1 year ago

Study Visit Requirements

Two visits, one before and one six months after surgery. Each of these visits will take 60 minutes. 

Principal Investigators

Kenneth Mroczek, MD

Smita Rao, PT, PhD

Answers to frequently asked questions (FAQs) about clinical trials

For more information about enrolling in this study, please contact Smita Rao, smita.rao@nyumc.org.