Pathology Department Jobs

Skok Lab: Postdoctoral Fellow

Position Summary:
The Skok lab is looking for a wet lab postdoc to work on exploring the impact of chromatin architecture on gene regulation in the context of normal and cancer cells through the use of CRISPR screens. The candidate should have experience in CRISPR and NGS techniques (chromosome conformation capture (3C), ChIP-seq, RNA-seq, ATAC-seq) is preferred. The postdoc will be expected to establish independent research projects and to generate high impact publications, which should provide fellows with an excellent opportunity for further career development in academia or pharmaceutical companies. View more at https://med.nyu.edu/faculty/jane-skok and https://skoklab.com.

To be considered, please submit a C.V., cover letter and names of 3 references to Jane Skok: Jane.Skok@med.nyu.edu.org and lab manager Fara Faye Regis: FaraFaye.Regis@nyulangone.org

Snuderl Lab: Assistant Research Technician

Position Summary: Responsible for performing basic laboratory experiments under general supervision as well as more advanced duties under direct supervision. Assists in designing and scientifically developing methodology for new research tests under the direction of the Principal Investigator. Participates in experiments, assay development including the scientific R&D bench work, manages validation projects, reviews data, quality control, and laboratory workflow processes. Also participates in result review and interpretation.

Job Responsibilities:

  • Assists in the process of designing and testing methodology and development protocols for new assays.
  • Extracts DNA, RNA, protein from fresh/frozen and formalin fixed paraffin embedded samples
  • Performs molecular analysis of humans tumor and non-tumor samples using genetic and epigenetic assays
  • Processing of raw data for downstream analysis.
  • Performs microscopy analysis of samples
  • Participates in development and validation of microfabricated chips for tumor analysis, extracts cells and performs necessary sorting and extraction for molecular analysis
  • Works closely with Core Facilities. Follows the sample preparation protocols and delivers samples to the cores for analysis in timely manner, communicates with the Coe Technicians about sample preparation and data analysis
  • Participates in designing and optimizing new protocols, including analysis of scientific literature and industry protocols, testing new reagents and assays, reviewing data quality and summarizing the results.
  • Follows all departmental biohazard, chemical, hazardous waste, infection control, and other safety police are followed.
  • Participates in academic activities of the Laboratory, reviews the methods and results for publication

Minimum Qualifications:
This is an entry level trainee position with no experience necessary and a Bachelor's of Science Degree in Life Sciences or a related field is preferred. Strong written and verbal communication skills are required.

Preferred Qualifications:
Bachelor's of Science Degree in Life Sciences or a related field preferred. MS with one year of experience in molecular biology. Experience with basic molecular techniques. Experience with microscopy such as confocal microscopy or Raman spectroscopy. Experience with DNA array profiling or immunofluorescence/immunohistochemistry techniques.

Please contact Stefanie.Castanza@nyulangone.org if you are an internal Pathology candidate and have interest in applying for this position.

Translational Immunology Center: Program Director

Position Summary: The Program Director will provide administrative leadership and direction in collaboration with the Director of the Translational Immunology Center. This individual will be solely responsible for overall management and operations, working independently to ensure the timely development and execution of activities across the Center. Because of the Center’s focus on high-dimensional technology and translational immunology, an individual with knowledge in one or more of these areas is strongly preferred.  

Job Responsibilities: Oversee all management and operations creatively and with strong vision. Ensure all areas of the Center align with its mission and are making strides, meeting goals, and producing deliverables. Weave together various arms of the Center to advance toward larger goals.

  1. Develop and maintain Center budgets and sub-budgets, including revisions, projections, and planning. Construct long-term financial plans and keep the Director well aware of future picture.
  2. Monitor the funding landscape, identify funding opportunities, and develop and write proposals and grants. Edit grant proposals, work with faculty and contributors to refine and develop pieces.
  3. Create long- and short-term project plans and ensure they are implemented.
  4. Plan and lead advisory board meetings, prepare materials and reports for senior institutional officials, and write progress summaries.
  5. Promote the Translational Immunology Center within NYU School of Medicine and work to foster expansion and collaboration.
  6. Foster alliances and partnerships with appropriate external agencies.
  7. Hire and oversee staff. 
  8. Thoughtfully monitor programs, processes, and outcomes, instituting changes when needed.
  9. Anticipate and ensure activities are supported by appropriate resources (personnel, fiscal, space, and equipment).
  10. Establish and maintain communication systems across teams, shape communications and messaging.
  11. Advance strategic initiatives and management of the day-to-day operations.

Minimum Qualifications
Skills: Strong manager with skills in change leadership, financial expertise, strategic planning, and grant writing. Master’s degree with 7-10 years of management experience.

Preferred Qualifications
PhD in translational biomedicine with a strong history of management.

If you are an internal NYULH employee with interest in this position, please contact Stefanie.Castanza@nyulangone.org

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Aifantis Lab: Research Technician

Position Summary: We have an exciting opportunity to join our team as a Research Technician. In this role, the successful candidate is responsible for performing basic lab experiments under general supervision, as well as more advanced duties under direct supervision, assisting senior and supervisory members of the lab. Emphasis on contribution to the organization of the lab, extensive inventory control of shared resources. Potential responsibility for maintenance of some animal colonies. The position would be to support the lab mainly in wet-lab bench work, but also some directed laboratory duties and general maintenance of the lab. Flexibility is key since this position is to fulfill responsibilities described below as required.

Job Responsibilities:

  • Lab Duties performs basic lab duties including routine technical tasks under general supervision as well as more advanced duties under direct supervision. Under supervision, performs standard laboratory procedures using established protocols, such as maintaining cell cultures requiring the use of sterile technique, preparing slides using staining techniques, general techniques in molecular biology and biochemistry. Maintains a record of results.
  • Support research by maintenance of inventory & stock control organization of vital lab resources including shared cell lines, plasmids, kits/reagents & consumables. Assists with the inventory and tracking of laboratory supplies. Assists in general maintenance of the lab as required.
  • Animal duties Handling of laboratory mice, genotyping and tracking of mouse colonies. Breeding and separation of pups. Performs animal handling procedures which may require injection of animals; collection/harvesting of tissues; blood draw and euthanasia. Completes monthly mouse colony census. Records information accurately and promptly, maintenance of online mouse database.
  • Assist in Developing Procedures - Assists in implementing new procedures and protocols to support experiments. Participates actively in developing, recommending and implementing new approved procedures, or modifications to existing protocols and procedures. Maintains and updates technical knowledge.
  • Communication/Relationship with Others - Cooperates, communicates and relates well to all levels of Medical Center. Listens carefully to others in order to respond appropriately, answer questions or obtain needed information. Communicates ideas, problems, suggestions, and messages in a timely and effective manner. Maintains the confidentiality of all research information.
  • Judgment/Decision-Making - Is able to recognize problems as they occur; and through the application of appropriate policy/ procedure, determine and/or recommends the appropriate solution. Seeks guidance as necessary for the performance of duties asks appropriate questions when in doubt and utilizes reference sources/materials to endure accuracy. Advises appropriate personnel of situations/problems requiring intervention or follow-up attention.
  • Participates and performs other related duties as required.

Minimum Qualifications: To qualify you must have a Bachelor's of Science Degree in Life Sciences or a related field with one year of experience. Advanced (beyond basic lab training will be accepted in lieu of experience as assessed by the hiring Principal Investigator). Effective oral and written communication skills required.

If you are an internal NYULH employee with interest in this position, please contact Stefanie.Castanza@nyulangone.org

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Assistant Director, Ion Channel Core Facility at NYU School of Medicine

Position Summary: We are establishing a new Ion Channel, Transporter and Immunology (ICTI) Core Facility at NYU School of Medicine to support scientists to study ion channels in immune cells and other cell types. The core facility is part of and supports a new program focused on Ion Channels and Immunity directed by Dr. Stefan Feske and will be located in recently created space in the new Science Building at the main campus of NYU School of Medicine. We are looking for a full-time assistant director of this new facility at the level of non-tenure track Research Assistant Professor.

Responsibilities of the ICTI Core Facility manager will be to assist scientists in the design, conduct and interpretation of ion channel measurements using manual and automated patch clamp systems, to maintain and upgrade equipment, to train new users and to be responsible for the overall management of the facility. The assistant director will additionally liaise with faculty at and outside of NYU and with other organizations to promote the facility. He/she reports to the core director, Dr. William Coetzee.

For information about the ICI program and the ICTI Core Facility, please visit:
https://med.nyu.edu/pathology/research/ion-channels-immunity-program

General requirements:

  • Ph.D. degree in physiology, biology or a related area.
  • Experience in independently designing, conducting and interpreting experiments. Highly motivated, responsible and very well organized with excellent attention to detail.
  • Effective oral and written communication skills in English
  • Willingness and ability to teach new users of ICTI core facility
  • Applicants with management experience and those interested in a long-term position are preferred.

Specific requirements:

  • Extensive hands-on experience in using and modifying manual patch clamp equipment to measure ion channel currents in cells
  • Solid background in ion channel physiology and data interpretation
  • Additional techniques desired but not necessary: Mammalian cell culture, molecular biology, fluorescence live cell imaging

Interested applicants should respond to this ad at https://apply.interfolio.com/72091 with a cover letter explaining their relevant work experience and interest in this position, a resume and the names, telephone numbers and e-mail addresses of three references.

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ICI Core: Research Scientist

A full-time research scientist position is available at New York University School of Medicine (NYUSoM) to manage a newly created core facility that supports scientists studying the function of ion channels in immune cells. We are looking for a candidate with hands-on experience in ion channel electrophysiology including patch clamp techniques.
Responsibilities of the successful candidate include helping scientists design, conduct and interpret ion channel current measurements using manual and automated patch clamp systems, maintain and upgrade equipment, train new users and manage the facility. The core facility is part of and supports a new program focused on Ion Channels and Immunity (ICI) directed by Dr. Stefan Feske, who will work closely with the new facility manager.

General requirements:

  • Masters or Ph.D. degree in physiology, biology or a related area.
  • Experience in independently designing, conducting and interpreting experiments.
  • Highly motivated, responsible and very well organized with excellent attention to detail.
  • Effective oral and written communication skills in English
  • Willingness and ability to teach new users of core facility
  • Applicants with management experience and those interested in a long-term position are preferred. 

Specific requirements:

  • Extensive hands-on experience in using and modifying manual patch clamp equipment to measure ion channel currents in cells
  • Soild background in ion channel physiology and data interpretation
  • Candidates with a background in immunology are particularly encouraged to apply
  • Additional techniques desired but not necessary: Mammalian cell culture, molecular biology, - fluorescence live cell imaging

Interested applicants should contact Stefanie.Castanza@nyulangone.org with a cover letter explaining their relevant work experience and interest in this position, a resume and the names, telephone numbers and e-mail addresses of three references.

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Bioinformatics Analyst

NYU Langone Health, a world-class, patient-centered, integrated, academic medical center, and one of the nation's premier centers for excellence in clinical care, biomedical research and medical education, is a seeking highly motivated, enthusiastic individual to join the Applied Bioinformatics Laboratories (ABL).

The successful candidate will work with the Feske lab and the Naik lab at the NYU School of Medicine to investigate the role of ion channels in immune cell function and the crosstalk between immune cells and adult stem cells, respectively. The successful candidate will have the opportunity to interface with wet-bench scientists and lead analyses on large datasets generated from state-of-the art next-generation sequencing technologies including single-cell approaches.

This is a great opportunity to quickly acquire high-in-demand bioinformatics skills, develop and publish new analysis tools/pipelines, analyze challenging datasets, and be a co-author on multiple high-impact manuscripts.

Responsibilities:

  • Work closely with bench scientists to understand and help accomplish their research goals
  • Analyze various types of sequencing data analysis (e.g. RNA-seq, ChIP-seq, ATAC-seq, Hi-C-seq, bisulfite sequencing, whole-genome sequencing Perform robust data quality control and validation
  • Assist in the design, implementation, and execution standard pipelines for routine genomics data analyses
  • Assist in the design, implementation and execution of customized pipelines for collaborative research projects
  • Adapt genomic data analysis pipelines in a rapidly evolving research environment
  • Work with bioinformatics team to integrate different types of genomics data
  • Assist in preparing concise presentations of computational results

Required Skills:

  • M.Sc. in Bioinformatics, Systems Biology, Computer Science or related field
  • Knowledge of biology and understanding of key and complex biological concepts (genes, pathways, cancer/immunity and/or stem cells)
  • Experience in Unix/Linux systems including HPC environments
  • Attention to detail and ability to work on multiple projects is necessary
  • Scripting languages: Python or Perl
  • Statistical packages: R (preferred) or Matlab.
  • 1+ years of experience with sequencing data (two of DNA-seq, RNA-seq (single cell or bulk), ATAC-seq and ChIP-seq)
  • 1+ years of experience creating customized sequencing analysis pipelines
  • Excellent communication skills with proficiency in written and oral English

Contact: Stefanie.Castanza@nyulangone.org if interested

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Research Grants Coordinator (Administration Staff Position)

Position Summary: Initial contact for Principal Investigators and the Sponsored Programs Administration (SPA) regarding research proposal preparation, submission, tracking and notice of awards for the Pathology Department. Coordinates the preparation and submission of grant proposals in accordance with agency and New York University policies and procedures. Coordinates the set-up of all active award contracts and budgets within SPA and InfoEd. Serves as a key contact for InfoEd, grant.gov, CRISP and eRa Common.

  1. Adheres strictly to sponsors deadlines, guidelines, instructions, and policy updates, confirming investigator's eligibility for each submission
  2. In cooperation with Principal Investigator (PI), prepares research proposals, including budgets and all non-scientific sections, in a manner compliant with all sponsor guidelines and University policies and procedures.
  3. Provides draft proposal for PI review prior to submission.
  4. Reviews all applications on behalf of the Department
  5. Maintains schedule to track all active and pending research grant submissions.
  6. Maintains database of past, current and forthcoming submissions
  7. Finalizes all required internal documentation for the office of SPA, including transmittal forms, financial interest disclosure forms for PIan
  8. key personnel, base salary forms, internal budget forms, application checklist, and others special forms as required
  9. Coordinates necessary internal documentation from IRB, IACUC, CLDR
  10. Follows institutional submission deadlines
  11. Assures compliance with University and School of Medicine policies and procedures including internal compliance requirements (IRB, IACUC)
  12. Secures required Department of Pathology signatures
  13. Submits applications to SPA on behalf of the Department
  14. Develops and maintains professional working relationships with SPA personnel
  15. Maintains updated database of pending awards status, including expected dates for notifications of awards
  16. Routinely follows-up on actual award notifications with PIs
  17. Processes paperwork required by SPA for authorization and approval to set up new accounts expeditiously
  18. Revises budget as needed
  19. Identifies and resolves administrative obstacles for account authorization and reauthorization
  20. Maintains the schedule of non-competitive renewals, progress reports and other sponsors' requirements deadlines. Notifies Pis 30 days in advance of due dates to assist them in meeting sponsors post-award administrative requirements and closing dates.
  21. Maintains and updates files of all past paper grant submissions
  22. Maintains and updates electronic files of past electronic submissions
  23. Keeps an updated database of faculty bio-sketches, disclosures, other resources, IRB, and IACUC protocol numbers
  24. Prepares and distributes schedule of applications and active awards spreadsheet weekly
  25. Proficiency with electronic submission process and updates and transitions to all new software and procedures quickly. Serves as the resident expert on relevant software applications in research administration
  26. Supports and facilitates faculty transition to online submissions
  27. Alerts supervisors of any new software requirements for online submissions and makes recommendations

Minimum Qualifications: Bachelor's degree in a related field or an equivalent combination of education and experience. Zero to two years of experience preparing grant proposals within a major academic center, processing funding applications with federal agencies, foundations and private donors. Demonstrated ability to work in a team environment and to manage competing priorities. Service oriented with excellent interpersonal, written, and oral communication skills. Must be detail oriented, able to work independently, able to consistently meet deadlines, and to make recommendations for process improvement.

Contact: Stefanie.Castanza@nyulangone.org if interested

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Research Technician

Position Summary: Responsible for conducting independent basic science experimentation based on research conducted in the assigned laboratory under the mentorship of a senior scientist. Individual is expected to seek to build a portfolio of research accomplishments in preparation for acquiring a higher degree in biomedical research or medicine.

Job Responsibilities:

  • Generates hypotheses and designs and performs experiments to test them.
  • Executes multiple experiments simultaneously over time independently.
  • Records all experimental findings in a laboratory notebook, analyze and interpret experimental findings.
  • Based on results, independently suggests and tests modifications to protocols.
  • Prepares figures and diagrams for presentations and publications.
  • Communicates results and collaborates with other professionals in the lab.
  • Demonstrates a significant level of intellectual input into the design of the project.
  • Presents findings at lab meeting, responds to challenges, and participates in exchanges of ideas to advance the science.
  • Reads and understands relevant scientific literature.
  • Contributes to the preparation of articles on research outcomes and progress and to the submission of same for publication.
  • Participates in the editing and proofing of grant proposals, annual grant reports, and manuscripts for publication and recommends modifications to the Principal Investigator.
  • After a period of time working in the laboratory, the candidate will be expected to train graduate students and post- doctoral fellows in experimental design, technique and performance.

Minimum Qualifications:
Bachelor’s degree and 2 years of experience

If you are an internal NYULH employee interested in this position, please contact Stefan.Feske@nyulangone.org.

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Feske Lab: Postdoctoral Positions

Postdoctoral positions are available in the Feske lab at New York University School of Medicine (NYUSoM) to study the role of ion channels in immune responses to infection, self (autoimmunity) and/or tumors.

The Feske has long-standing expertise in investigating calcium signaling pathways in cells of the immune system. We study the molecular regulation of calcium release-activated channels (CRAC) formed by ORAI and STIM proteins and investigate their role in the physiology of immune cells. We use mice with targeted deletion of CRAC channels and human patients with mutations in CRAC channel genes to investigate how calcium signals control immune responses to infection and tumors, and in autoimmunity and inflammation. Our research is published in leading journals including Nature, New England Journal of Medicine, Immunity, Nature Immunology, Nature Communications, J Exp Med, J Clin Invest and PNAS. For more information, please visit: http://labs.pathology.med.nyu.edu/feske-lab/.

Besides CRAC channels, other ion channels are expressed in T cells and other immune cells that control their function. The Feske lab is systematically investigating which ion channels regulate adaptive and innate immune responses to pathogens, tumors, and self. For these projects, we are seeking highly motivated and creative postdoctoral scientists to elucidate the molecular mechanisms of ion channel function in immune cell and their role in immune responses in vitro and in vivo using animal models of immunity.

Candidates should have a recent MD, PhD or MD/PhD degree and a strong background in immunology, specifically the use of animal models or signal transduction. Candidates with experience in ion channel function in immune cells or related cell types are especially encouraged to apply. A background in molecular and cell biology is desired. Please send a cover letter explaining relevant work experience and interests, a CV, and the contact information of three references to Dr. Feske at feskes01@nyumc.org.

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