Pathology Department Jobs

Assistant Research Technician, Molecular Pathology laboratory

Position Summary: Assists in designing and scientifically developing methodology for new research tests under the direction of the Principal Investigator. Participates in experiments, assay development including the scientific R&D bench work, manages validation projects, reviews data, quality control, and laboratory workflow processes. Also participates in result review and interpretation.

  1. Assists in the process of designing and testing methodology and development protocols for new assays.
  2. Extracts DNA, RNA, protein from fresh/frozen and formalin fixed paraffin embedded samples
  3. Performs molecular analysis of humans tumor and non-tumor samples using genetic and epigenetic assays
  4. Processing of raw data for downstream analysis.
  5. Performs microscopy analysis of samples
  6. Participates in development and validation of microfabricated chips for tumor analysis, extracts cells and performs necessary sorting and extraction for molecular analysis
  7. Works closely with Core Facilities. Follows the sample preparation protocols and delivers samples to the cores for analysis in timely manner, communicates with the Coe Technicians about sample preparation and data analysis
  8. Participates in designing and optimizing new protocols, including analysis of scientific literature and industry protocols, testing new reagents and assays, reviewing data quality and summarizing  the results.
  9. Follows all departmental biohazard, chemical, hazardous waste, infection control, and other safety police are followed.
  10. Participates in academic activities of the Laboratory, reviews the methods and results for publication

Minimum Qualifications: MS with one year of experience in molecular biology. Experience with basic molecular techniques.

Preferred Qualifications: Experience with microscopy such as confocal microscopy or Raman spectroscopy. Experience with DNA array profiling or immunofluorescence/immunohistochemistry techniques.

Working Conditions/Physical Demands:  Position requires flexible working schedule. Laboratory setting with exposure to various chemicals and reagents and body fluids and human tissue. Limited physical demands.

Please contact Stefanie.Castanza@nyulangone.org if you are an internal NYU Langone employee with interest in this position

Assistant/Associate Research Technician

Position Description: Under the supervision of Christopher William, M.D., Ph.D., in the Department of Pathology, the technician will conduct a variety of standard molecular biological and histological methods, acquire significant knowledge in the fields of neurodegenerative disease and postnatal mouse visual system development and gain experience in molecular biology, protein biochemistry, microscopic and histologic techniques and the study of disease processes in animal models. The research includes microsurgery on the mouse eye and eye lid, cranial surgery and in vivo imaging in awake mice. The technician will learn to independently design, plan and carry out studies.    The research effort is focused on improving our understanding of the pathologic processes underlying neurodegeneration in Alzheimer’s disease and neurodevelopmental impairment in Down syndrome, primarily by exploring the roles that synaptic plasticity and synaptic dysfunction play in both disease processes. In the developing mouse visual system, activity-dependent competition and synaptic plasticity shape the wiring of responses in the visual cortex to sensory input from left and right eyes. This process can be challenged by closure of one eye for 4-6 days, a process that causes the visual cortex to shift responsiveness in favor of the non-deprived eye. Mouse models of Alzheimer’s disease and of Down syndrome exhibit defects in this basic plastic response, suggesting that this system can be used to better understand circuit dysfunction in both diseases. An additional goal of these studies is to develop an approach in which potential therapies can be tested for their ability to rescue synaptic function in the context of the intact, functioning, mouse model brain. Human tissue from disease and control brains may also be studied to complement and test hypotheses driven by animal model work in these projects.

Job Responsibilities:

  1. DNA related techniques: preparation of plasmids, gel electrophoresis, cloning of vector constructs
  2. Histologic studies: routine histologic stains, immunohistochemistry, in situ hybridization
  3. Mouse husbandry, assistance in maintenance of a mouse colony and performance of microsurgery including, but not limited to eye lid suture, eye enucleation and cranial window placement
  4. Protein chemistry: protein expression, protein quantification, Western blotting, co-immunoprecipitation studies and pulldown experiments
  5. Procurement of supplies, the scientific maintenance of the laboratory and the organization of research material
  6. Image analysis with computer programs, data management, laboratory notebook maintenance
  7. Library research and database analysis, preparation of manuscripts, upkeep of written records, of experimental procedures and data analysis
  8. Instruct students and others in molecular biology methodology and laboratory instrument operation and participate and present data at lab meetings

Minimum Qualifications: A Bachelor's of Science Degree in Life Sciences or a related field is preferred. Experience in laboratory specific organization of processes, operation and maintenance of equipment, and documentation of performed experiments is preferred, but not required. Strong written and verbal communication skills are required. Must be able to multi-task and work independently.

Please contact Stefanie.Castanza@nyulangone.org if you are an internal NYU Langone employee interested in this position.

Bioinformatics Analyst

NYU Langone Health, a world-class, patient-centered, integrated, academic medical center, and one of the nation's premier centers for excellence in clinical care, biomedical research and medical education, is a seeking highly motivated, enthusiastic individual to join the Applied Bioinformatics Laboratories (ABL).

The successful candidate will work with the Feske lab and the Naik lab at the NYU School of Medicine to investigate the role of ion channels in immune cell function and the crosstalk between immune cells and adult stem cells, respectively. The successful candidate will have the opportunity to interface with wet-bench scientists and lead analyses on large datasets generated from state-of-the art next-generation sequencing technologies including single-cell approaches.

This is a great opportunity to quickly acquire high-in-demand bioinformatics skills, develop and publish new analysis tools/pipelines, analyze challenging datasets, and be a co-author on multiple high-impact manuscripts.

Responsibilities:

  • Work closely with bench scientists to understand and help accomplish their research goals
  • Analyze various types of sequencing data analysis (e.g. RNA-seq, ChIP-seq, ATAC-seq, Hi-C-seq, bisulfite sequencing, whole-genome sequencing Perform robust data quality control and validation
  • Assist in the design, implementation, and execution standard pipelines for routine genomics data analyses
  • Assist in the design, implementation and execution of customized pipelines for collaborative research projects
  • Adapt genomic data analysis pipelines in a rapidly evolving research environment
  • Work with bioinformatics team to integrate different types of genomics data
  • Assist in preparing concise presentations of computational results

Required Skills:

  • M.Sc. in Bioinformatics, Systems Biology, Computer Science or related field
  • Knowledge of biology and understanding of key and complex biological concepts (genes, pathways, cancer/immunity and/or stem cells)
  • Experience in Unix/Linux systems including HPC environments
  • Attention to detail and ability to work on multiple projects is necessary
  • Scripting languages: Python or Perl
  • Statistical packages: R (preferred) or Matlab.
  • 1+ years of experience with sequencing data (two of DNA-seq, RNA-seq (single cell or bulk), ATAC-seq and ChIP-seq)
  • 1+ years of experience creating customized sequencing analysis pipelines
  • Excellent communication skills with proficiency in written and oral English

Contact: Stefanie.Castanza@nyulangone.org if interested

Research Grants Coordinator (Administration Staff Position)

Position Summary: Initial contact for Principal Investigators and the Sponsored Programs Administration (SPA) regarding research proposal preparation, submission, tracking and notice of awards for the Pathology Department. Coordinates the preparation and submission of grant proposals in accordance with agency and New York University policies and procedures. Coordinates the set-up of all active award contracts and budgets within SPA and InfoEd. Serves as a key contact for InfoEd, grant.gov, CRISP and eRa Common.

  1. Adheres strictly to sponsors deadlines, guidelines, instructions, and policy updates, confirming investigator's eligibility for each submission
  2. In cooperation with Principal Investigator (PI), prepares research proposals, including budgets and all non-scientific sections, in a manner compliant with all sponsor guidelines and University policies and procedures.
  3. Provides draft proposal for PI review prior to submission.
  4. Reviews all applications on behalf of the Department
  5. Maintains schedule to track all active and pending research grant submissions.
  6. Maintains database of past, current and forthcoming submissions
  7. Finalizes all required internal documentation for the office of SPA, including transmittal forms, financial interest disclosure forms for PIan
  8. key personnel, base salary forms, internal budget forms, application checklist, and others special forms as required
  9. Coordinates necessary internal documentation from IRB, IACUC, CLDR
  10. Follows institutional submission deadlines
  11. Assures compliance with University and School of Medicine policies and procedures including internal compliance requirements (IRB, IACUC)
  12. Secures required Department of Pathology signatures
  13. Submits applications to SPA on behalf of the Department
  14. Develops and maintains professional working relationships with SPA personnel
  15. Maintains updated database of pending awards status, including expected dates for notifications of awards
  16. Routinely follows-up on actual award notifications with PIs
  17. Processes paperwork required by SPA for authorization and approval to set up new accounts expeditiously
  18. Revises budget as needed
  19. Identifies and resolves administrative obstacles for account authorization and reauthorization
  20. Maintains the schedule of non-competitive renewals, progress reports and other sponsors' requirements deadlines. Notifies Pis 30 days in advance of due dates to assist them in meeting sponsors post-award administrative requirements and closing dates.
  21. Maintains and updates files of all past paper grant submissions
  22. Maintains and updates electronic files of past electronic submissions
  23. Keeps an updated database of faculty bio-sketches, disclosures, other resources, IRB, and IACUC protocol numbers
  24. Prepares and distributes schedule of applications and active awards spreadsheet weekly
  25. Proficiency with electronic submission process and updates and transitions to all new software and procedures quickly. Serves as the resident expert on relevant software applications in research administration
  26. Supports and facilitates faculty transition to online submissions
  27. Alerts supervisors of any new software requirements for online submissions and makes recommendations

Minimum Qualifications: Bachelor's degree in a related field or an equivalent combination of education and experience. Zero to two years of experience preparing grant proposals within a major academic center, processing funding applications with federal agencies, foundations and private donors. Demonstrated ability to work in a team environment and to manage competing priorities. Service oriented with excellent interpersonal, written, and oral communication skills. Must be detail oriented, able to work independently, able to consistently meet deadlines, and to make recommendations for process improvement.

Contact: Stefanie.Castanza@nyulangone.org if interested

Computational Technician – Skok Lab

The Skok lab is looking for a bioinformatician to work at the interface of chromatin structure, transcriptional regulation and computational biology. We need someone to provide computational support to our wet lab postdocs as well as someone who will drive their own project to develop new methods to analyze genome-wide sequencing data. We will apply these tools for analyzing how changes in chromatin architecture impact cancer. Applicants should have experience with analysis of genomics data sets preferably chromosome conformation capture, HiChIP, RNA-seq, ATAC-seq and ChIP-seq.

To apply or to obtain more information about the position please contact Dr Skok at Jane.skok@nyulangone.org. Applicants should include a CV, a one-page research statement and the names of three referees.

Postdoctoral Fellow – Skok Lab

The Skok lab is looking for a wet lab postdoc to work on gene regulation and chromosome organization in cancer. We are looking for candidates with a strong publication record that are within the first year of completing a PhD. Experience in chromosome conformation capture (3C), CRISPR, as well as other NGS techniques is preferable. Candidates are expected to establish independent research projects and to generate high impact publications, which should provide postdoctoral fellows with an excellent opportunity for further career development in academia or pharmaceutical companies.

To apply or to obtain more information about the position please contact Dr Skok at Jane.skok@nyulangone.org. Applicants should include a CV, a one-page research statement and the names of three referees.

Research Scientist

The Feske lab is open to interviewing any internal Pathology candidates interested in the following position: Research Scientist

Position Summary: Responsible for collaborating with Principal Investigators (PI) and working independently within the scientific framework of the PI's laboratory.

Job Responsibilities:

  1. Initiates, interprets, organizes, executes, and coordinates research assignments critical to department's mission.
  2. Formulates and conducts research on problems of considerable scope and complexity.
  3. Explores subject area and defines scope and selection of problems for investigation through conceptually related studies or series of projects of lesser scope.
  4. Makes decisions and recommendations that have a major impact on extensive scientific research activities.
  5. Develops new ideas that promote current research. Exercises a high degree of creativity, foresight, and mature judgment in planning, organizing, and guiding extensive scientific research programs and activities of outstanding novelty and/or importance.
  6. May manage the operations of a lab for the Principal Investigator by supervising Post Docs and technicians.
  7. Ensures timely and accurate completion of research projects.
  8. May provide students with technical guidance and direction in the operation of various sample preparation techniques, extraction lines, and equipment as well as general laboratory practices and safety protocols.
  9. May seek grant funding from external sources in support of their independent research projects with consent of the PI and the Department Chair. May participate in writing grant proposals.
  10. May be responsible research/lab quality control and compliance.
  11. May develop protocol for the collection and quality of research data.
  12. Develops research techniques and methodologies.
  13. May determine and establish laboratory policies, procedures and practices.
  14. Maintains a thorough knowledge of the advances in specialized fields through attendance of scientific conferences.
  15. May make significant contributions to scientific papers. Is a resource/ author/ co-author for reports and presentations.
  16. May provide recommendations for equipment purchases and for the redesign of lab space.
  17. May coordinate the activity and experimental design between various labs, scientific staff, and collaborators. Identifies and resolves technical problems.
  18. May serve on internal committees to help further goals of research projects and bring new expertise to the research program.
  19. Oversees the maintenance and upkeep of all instruments and laboratory facilities.
  20. 20 Performs other related duties as assigned.

Minimum Qualifications:
MD or PhD and 5 years experience. Critical thinking skills, strong organizational and time management skills, including ability to work independently and prioritize projects. Excellent verbal and written communication skills.

Please contact Stefanie.Castanza@nyumc.org if you are an internal-Pathology employee & have interest in applying for this position.

Associate Research Technician

The Feske lab is open to interviewing any internal Pathology candidates interested in the following position: Research Technician

Position Summary: A full-time research technician / lab manager position is available in a basic research laboratory at New York University Langone Medical Center (NYULMC) in midtown Manhattan. Research in the lab is focused on the regulation of immune cell function by ion channels and immune responses to infection, tumors and in autoimmune diseases. Most of the research is conducted using various strains of transgenic mice. For information about the laboratory please visit: http://labs.pathology.med.nyu.edu/feske-lab/

Job Responsibilities:

  1. Help with management of the transgenic mouse colony (including genotyping).
  2. General lab management (including dealing with regulatory and compliance issues).
  3. Generation of recombinant DNA plasmids.
  4. Cell culture and various immunological methods.
  5. Assist postdoctoral fellows in their projects.
  6. Performs other duties as assigned.

Minimum Qualifications:
- B.Sc. or M.Sc. in biology, biochemistry or a related area.
- Prior laboratory experience in a research lab.
- Highly motivated, responsible and very well organized with excellent attention to detail.
- Good communication skills in oral and written English.
- Candidates with a background in immunology are particularly encouraged to apply.
- Applicants interested in a long-term position are preferred.

Specific Required Skills (the successful candidate will have most of these skills):
- Mouse colony management including handling, breeding and genotyping transgenic mice
- Sterile cell culture (mammalian cells, immune cells)
- PCR, cloning recombinant DNA, basic molecular biology methods
- Immunohistochemistry, ELISA
- Flow cytometry (FACS)
- Protein biochemistry such as Western blotting
- Fluorescence microscopy and/or live-cell imaging

Please contact Stefanie.Castanza@nyumc.org if you are an internal-Pathology employee & have interest in applying for this position.

Feske Lab: Postdoctoral Positions

Postdoctoral positions are available in the Feske lab at New York University School of Medicine (NYUSoM) to study the role of ion channels in immune responses to infection, self (autoimmunity) and/or tumors.

The Feske has long-standing expertise in investigating calcium signaling pathways in cells of the immune system. We study the molecular regulation of calcium release-activated channels (CRAC) formed by ORAI and STIM proteins and investigate their role in the physiology of immune cells. We use mice with targeted deletion of CRAC channels and human patients with mutations in CRAC channel genes to investigate how calcium signals control immune responses to infection and tumors, and in autoimmunity and inflammation. Our research is published in leading journals including Nature, New England Journal of Medicine, Immunity, Nature Immunology, Nature Communications, J Exp Med, J Clin Invest and PNAS. For more information, please visit: http://labs.pathology.med.nyu.edu/feske-lab/.

Besides CRAC channels, other ion channels are expressed in T cells and other immune cells that control their function. The Feske lab is systematically investigating which ion channels regulate adaptive and innate immune responses to pathogens, tumors, and self. For these projects, we are seeking highly motivated and creative postdoctoral scientists to elucidate the molecular mechanisms of ion channel function in immune cell and their role in immune responses in vitro and in vivo using animal models of immunity.

Candidates should have a recent MD, PhD or MD/PhD degree and a strong background in immunology, specifically the use of animal models or signal transduction. Candidates with experience in ion channel function in immune cells or related cell types are especially encouraged to apply. A background in molecular and cell biology is desired. Please send a cover letter explaining relevant work experience and interests, a CV, and the contact information of three references to Dr. Feske at feskes01@nyumc.org.

FGP Billing Coordinator

NYU Pathology Associates is open to interviewing any internal Pathology candidates interested in the following position: FGP Billing Coordinator

Position Summary: Analyzes, bills, follows-up, corrects and enters claim information in the pathology billing system as assigned by management.

Job Responsibilities:

  1. Performs daily tasks in assigned work queues and according to manager assignments.
  2. Follows workflows provided in training classes for the department clinical systems.
  3. Uses payer websites, billing system and/or coders, or other responsible persons.
  4. Provides input on system edits, processes, policies, and billing procedures to ensure maximization of revenues.
  5. Performs billing tasks assigned by management which may include data entry, claim review, charge review, or other related responsibilities.

Minimum Qualifications: Experience in medical billing, insurance or related duties; or formal training or education in medical billing that provides the required knowledge and abilities. Knowledge of both Current Procedures Codes (CPT) and International Class of Diseases Codes (ICD-10) utilized in medical billing. Holds a current Certified Procedural Coder (CPC) certificate.

Please contact janet.alexis@nyumc.org if you are an internal-Pathology employee & have interest in applying for this position.