Gastrointestinal Dysfunction in Parkinson’s Disease
Constipation is a prominent non-motor complication of Parkinson’s disease (PD) that may manifest many years prior to the onset of traditional motor symptoms, however, the nature of gastrointestinal (GI) dysfunction in PD remains poorly understood. We are working with gastroenterologists to systematically study the physiological nature of constipation in PD patients. Using state-of-the-art methods to assess GI function, we aim to determine whether PD constipation is unique in its etiology and requires specialized treatment modalities. We are also intensely interested in understanding the role of gut health in the pathogenesis of Parkinson’s disease.