Recent Publications:

Klein, H. L. (2008) The causes and consequences of Rad51 overexpression for normal and tumor cells. DNA Repair (Amst) 7: 686-693. (PDF)

Kwon, Y., Chi, P., Roh, D. H., Klein, H. and Sung, P. (2007) Synergistic
action of the Saccharomyces cerevisiae homologous recombination factors Rad54 and Rad51 in chromatin remodeling. DNA Repair (Amst) 6: 1496-1506. (PDF)

Joseph San Filippo, Patrick Sung and Hannah Klein. "Mechanism of Eukaryotic Homologous Recombination".  Annual Review of Biochemistry
Vol. 77: 229-257 (Volume publication date July 2008). First published online as a Review in Advance on February 14, 2008. (PDF)

Kwon, YH, Seong, C, Chi, P, Greene, EC, Klein, H, Sung, P. "ATP-dependent chromatin remodeling by the Saccharomyces cerevisiae homologous recombination factor Rdh54," Journal of biological chemistry 2008 APR 18;283(16):10445-10452. (#J0137578) (PDF)

Klein, Hannah L. "Reversal of fortune: Rad5 to the rescue [comment]," Molecular cell 2007 Oct 26;28(2):181-3. (MEDL:17964257 PMID: 17964257 #J0132732) (PDF)

Chi P; Kwon Y; Seong C; Epshtein A; Lam I; Sung P; Klein HL. "Yeast recombination factor Rdh54 functionally interacts with the Rad51 recombinase and catalyzes Rad51 removal from DNA". Journal of biological chemistry. 2006; (#J0118696) (PDF)

Chi, P; Kwon, Y; Seong, C; Epshtein, A; Lam, I; Sung, P; Klein, HL. "Yeast recombination factor Rdh54 functionally interacts with the Rad51 recombinase and catalyzes Rad51 removal from DNA". Journal of biological chemistry. 2006; 281: 26268 (#J0120489) (PDF)

Klein, Hannah L. "A SUMOry of DNA replication: synthesis, damage, and repair [comment]". Cell. 2006; 127: 455 (#J0122415) (PDF)

Sung, P; Klein, H. "Mechanism of homologous recombination: mediators and helicases take on regulatory functions". Nature reviews. Molecular cell biology. 2006; 7: 739 (#J0122109) (PDF)

Monroe DS Jr; Leitzel AK; Klein HL; Matson SW. "Biochemical and genetic characterization of Hmi1p, a yeast DNA helicase involved in the maintenance of mitochondrial DNA". Yeast. 2005; 22: 1269 (#J0118697)

Krejci L; Macris M; Li Y; Van Komen S; Villemain J;
Ellenberger T; Klein H; Sung P. "Role of ATP hydrolysis in the antirecombinase function of Saccharomyces cerevisiae Srs2 protein". Journal of biological chemistry. 2004; 279: 23193 (#J0118699) (PDF)

Smirnova M; Van Komen S; Sung P; Klein HL. "Effects of tumor-associated mutations on Rad54 functions". Journal of biological chemistry. 2004; 279: 24081 (#J0076832) (PDF)

Xu H; Boone C; Klein HL. "Mrc1 is required for sister chromatid cohesion to aid in recombination repair of spontaneous damage". Molecular & cellular biology. 2004; 24: 7082 (#J0118698)

Krejci L; Van Komen S; Li Y; Villemain J; Reddy MS; Klein H; Ellenberger T; Sung P. "DNA helicase Srs2 disrupts the Rad51 presynaptic filament". Nature. 2003; 423: 305 (#J0049866) (PDF)

Van Komen S; Reddy MS; Krejci L; Klein H; Sung P. "ATPase and DNA Helicase Activities of the Saccharomyces cerevisiae Anti-recombinase Srs2". Journal of biological chemistry. 2003; 278: 44331 (#J0053095) (PDF)