Electrocorticography (ECoG)

Example of intracranial ERP responses to an auditory speech stimulus recorded on a 8×8 macro-electrode grid

Example of intracranial ERP responses to an auditory speech stimulus recorded on a 8×8 macro-electrode grid

A core research area in our laboratory is the study of brain function in humans using subdural electrodes implanted inside the cranium. For purely clinical reasons, patients with epilepsy are sometimes implanted with such electrodes to localize their seizure onset prior to surgical therapy. This gives us the chance to study brain processes with unmatched temporal and spatial resolution, including recordings from single-units, without any additional risk to the patient. All our studies adhere to the strict ethical guidelines of the NYU School of Medicine guidelines for research involving human subjects and have current Institutional Review Board approval. Patient volunteers often enjoy participating in our sensory and cognitive experiments to alleviate some of the boredom an extended hospital visit can entail. Furthermore, patients see the value of our research and are often very interested in contributing to the advancement of scientific knowledge and medical treatments.

A clear advantage of ECoG over other neuroimaging methods is that it possess both high spatial (mm scale) and temporal (ms scales) resolution. The spatial resolution of iEEG varies depending on recording equipment. We are currently able to obtain both single and multi-unit recordings from extra-cellular laminar and Utah array microelectrodes and local filed potential recordings from surface strips and grids of electrodes, as well as depth electrodes (often placed in the hippocampus and amygdala). A further advantage of ECoG over MEG and scalp EEG is that intracranial recordings are not so susceptible to artifactual contamination from muscle movements and eye blinks, which regularly impair the quality of MEG and scalp EEG recordings, especially during language production.

One of the prerequisites of recording directly from the human brain is that the subject is a neurological patient who suffers from epilepsy. This raises the issue that the brain responses recorded from these patients may contain abnormal neuronal patterns and may not generalize to the general, healthy population. This possibility can never be ruled out, but steps can be taken to minimize its likelihood, such as recording from sites distant to the seizure focus and recording from patients with different etiologies, pathologies and anticonvulsant medications. Data contamination by interictal spiking is a prevalent problem and can be minimized by selecting testing periods where the subject is under anticonvulsive medication and by increasing the number of stimulus trials in case data have to be discarded. In many of our experiments we are also performing MEG and/or fMRI in healthy subjects and patients, allowing validation of the ECoG findings with other imaging methods in healthy subjects. One particular ECoG signal, the activity in the high gamma power (HGP) band (70-190 Hz, also called “broadband activity”), is of special interest to us since it possesses a high signal-to-noise ratio and is likely to reflect the aggregate spiking activity of neuronal populations immediately underneath the electrode and is thus directly related to increases and decreases in local neuronal activity. 

You can find out more about the NYU ECoG Center at their web page: http://ecog.med.nyu.edu/

Example publications:
Thesen T., McDonald C.R., Carlson C., Doyle W., Cash S., Sherfey J., Felsovalyi O., Girard H., Barr W., Devinsky O., Kuzniecky R., Halgren E. Sequential then interactive processing of letters and words in the left fusiform gyrus. Nature Communication. (2012) Dec 18;3:1284. PMID: 23250414. [Pubmed] [PDF]

Cogan G.B., Thesen T., Carlson C., Doyle W., Devinsky O., Pesaran B. (2014). Sensory-motor transformations for speech occur bilaterally. Nature, AOP. [Pubmed] [PDF]

Honey C. J., Thesen T., Donner T. H., Silbert L. J., Carlson C. E., Devinsky O., Doyle W. K., Rubin N., Heeger D. J., Hasson U. Slow cortical dynamics and the accumulation of information over long timescales. Neuron. 2012 Oct 18;76(2):423-34. PMID: 23083743. [Pubmed] [PDF]

Quinn B. T., Carlson C., Doyle W., Cash S.S., Devinsky O., Spence C., Halgren E. & Thesen T. (2014). Intracranial cortical responses during visual-tactile integration in humans. Journal of Neuroscience. Jan 01, 2014. [Pubmed] [PDF]

162 thoughts on Electrocorticography (ECoG)

  1. Pingback: Scientists Create First ‘Brain-To-Text’ System | Health Units - Health Units

  2. Pingback: Annemarie Sollenberger

  3. Pingback: Brain-Computer Interface (BCI) Technology - World of Standards

  4. Pingback: writeessay

  5. Pingback: Ambika Ahuja Jaipur Escorts

  6. Pingback: Neha Tyagi Escorts Services In Jaipur



  9. Pingback: Dhruvi Jaipur Escorts


  11. Pingback: Heena Khan Bangalore Escorts

  12. Pingback: Jiya Malik High Profile Jaipur Escorts Model



  15. Pingback: Selly Arora Independent Bangalore Escorts

  16. Pingback: Enjoy With Jaipur Escorts Tanisha Walia


  18. Pingback: Bristy Roy Independent Bangalore Escorts



  21. Pingback: Bangalore Escorts Sneha Despandey


  23. Pingback: XXX PORN Radhika Apte Model Escort

  24. Pingback: GOA ESCORTS EVA J LAW

  25. Pingback: Fiza Khan Kolkata Escorts Services

  26. Pingback: Ruby Sen Kolkata Independent Escorts Services

  27. Pingback: Diana Diaz Goa Independent Escorts Services

  28. Pingback: Diksha Arya Independent Escorts Services in Kolkata

  29. Pingback: Devika Kakkar Goa Escorts Services

  30. Pingback: Rebecca Desuza Goa Independent Escorts Services

  31. Pingback: Yamini Mittal Independent Escorts Services in Goa

  32. Pingback: Simmi Mittal Kolkata Escorts Services

  33. Pingback: Kolkata Escorts Services Ragini Mehta

  34. Pingback: Navya Sharma Independent Kolkata Escorts Services

  35. Pingback: Elisha Roy Goa Independent Escorts Services

  36. Pingback: Alisha Oberoi Independent Escorts in Kolkata

  37. Pingback: Divya Arora Goa Independent Escorts Services

  38. Pingback: Simran Batra Independent Escorts in Kolkata

  39. Pingback: Ashna Ahuja Escorts Services in Kolkata

  40. Pingback: Sofia Desai Escorts Services in Goa

  41. Pingback: Goa Escorts Services Drishti Goyal

  42. Pingback: Mayra Khan Escorts Services in Kolkata

  43. Pingback: Sruthi Pathak Escorts in Bangalore

  44. Pingback: Ambika Ahuja Jaipur Escorts Services

  45. Pingback: click

  46. Pingback: sirius movs3322

  47. Pingback: links hit3258

  48. Pingback: new siriustube248

  49. Pingback: med.nyu.edu350

  50. Pingback: med.nyu.edu903

  51. Pingback: comment500

  52. Pingback: comment359

  53. Pingback: comment642

  54. Pingback: comment344

  55. Pingback: comment405

  56. Pingback: comment797

  57. Pingback: comment796

  58. Pingback: comment132

  59. Pingback: comment901

  60. Pingback: comment381

  61. Pingback: comment603

  62. Pingback: comment328

  63. Pingback: comment170

  64. Pingback: comment601

  65. Pingback: comment363

  66. Pingback: comment880

  67. Pingback: comment773

  68. Pingback: comment129

  69. Pingback: comment169

  70. Pingback: comment893

  71. Pingback: comment178

  72. Pingback: comment470

  73. Pingback: comment833

  74. Pingback: comment852

  75. Pingback: comment447

  76. Pingback: comment384

  77. Pingback: comment40

  78. Pingback: comment637

  79. Pingback: comment499

  80. Pingback: comment663

  81. Pingback: comment944

  82. Pingback: comment120

  83. Pingback: comment646

  84. Pingback: comment621

  85. Pingback: comment560

  86. Pingback: comment114

  87. Pingback: comment35

  88. Pingback: comment931

  89. Pingback: comment280

  90. Pingback: comment783

  91. Pingback: comment975

  92. Pingback: comment798

  93. Pingback: comment902

  94. Pingback: comment542

  95. Pingback: comment213

  96. Pingback: comment919

  97. Pingback: comment554

  98. Pingback: comment67

  99. Pingback: comment510

  100. Pingback: comment231

  101. Pingback: comment648

  102. Pingback: comment582

  103. Pingback: Sruthi Pathak Bangalore Female Escorts

  104. Pingback: new siriustube501 abdu23na4384 abdu23na64

  105. Pingback: newtube sirius247 abdu23na827 abdu23na50

  106. Pingback: sfgjidfgn849 afeu23na5514 abdu23na42

  107. Pingback: download on mobile646 afeu23na2596 abdu23na75

  108. Pingback: jigdf43g696 afeu23na7530 abdu23na55

  109. Pingback: 995IsfJkSen

  110. Pingback: hdmobilesex.me

  111. Pingback: Sruthi Pathak Bangalore Escorts Services

  112. Pingback: Trully Independent Bangalore Escorts Services

  113. Pingback: Fiza Khan Kolkata Independent Call Girls Services

  114. Pingback: Ruchika Roy Kolkata Escorts Call Girls Services

  115. Pingback: nsfwtophookup.eu nsfwtophookup.eu Sex dating yjN

  116. Pingback: Fiza Khan Kolkata Independent Escorts Call Girls Services

  117. Pingback: Fiza Khan Kolkata Call Girls Escorts Services

  118. Pingback: Diksha Arya Kolkata Escorts Call Girls Services

  119. Pingback: Diksha Arya Kolkata Independent Escorts Call Girls Services

  120. Pingback: Cheap

  121. Pingback: Nidika Offer Call Girls in Bangalore

  122. Pingback: WOW Blog

  123. Pingback: xxlhq.top article

  124. Pingback: xxlhq.xyz article

  125. Pingback: xxlph.xyz article

  126. Pingback: adultpics.top article

  127. Pingback: xxxpics xyz

  128. Pingback: xxlph xyz

  129. Pingback: pornph xyz

  130. Pingback: xxxpics.xyz article

  131. Pingback: xxxph top

  132. Pingback: xxlph.top article

  133. Pingback: xyz

  134. Pingback: adulthq top

  135. Pingback: xxxhd.top article

  136. Pingback: xnxxhd top

  137. Pingback: xxxhq top

  138. Pingback: pornph.xyz article

  139. Pingback: xxlhd xyz

  140. Pingback: adultpics top

  141. Pingback: xxxhq.top article

  142. Pingback: xxxph xyz

  143. Pingback: adulthq.xyz article

  144. Pingback: adultph.top article

  145. Pingback: xnxxhd.top article

  146. Pingback: xxlhd.xyz article

  147. Pingback: pornph.top article

  148. Pingback: xxlhq xyz

  149. Pingback: xxlph top

  150. Pingback: xxxph.top article

  151. Pingback: adultph top

  152. Pingback: adulthq.top article

  153. Pingback: xxlhq top

  154. Pingback: adulthd top

  155. Pingback: adulthd xyz

  156. Pingback: pornph top

  157. Pingback: adulthd.top article

  158. Pingback: adulthq xyz

  159. Pingback: adultph.xyz article

  160. Pingback: xxxph.xyz article

  161. Pingback: xxxhd top

  162. Pingback: adulthd.xyz article

Comments are closed.