Publications

Camacho-Perez, M., Basu, J., Trimbuch, T., Chang, S., Pulido, C., Chang, S., Dulubova, I., Rady, M., Rizo J. and Rosenmund C. Heterodimerization of Munc13 C2A domain with RIM regulates synaptic vesicle docking and priming. Nature Communications 2017; 8: 15293.

Basu, J., Zaremba J., Cheung, S.K., Hitti F.L., Zemelman, B.V., Losonczy, A., Siegelbaum, S.A. (2016) Gating of hippocampal activity, plasticity and memory by entorhinal cortex long-range inhibition. Science: Vol. 351, Issue 6269.  
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Kupferman, J., Basu, J., Russo, M. J., Guevarra, J.D., and Siegelbaum, S.A. (2014) Reelin signaling is required for the enrichment of ion channels in pyramidal neuron distal tuft dendrites. Cell, 2014 (07) 035Sept 4.

Basu, J., Srinivas K. V., Cheung, S.K., Taniguchi, H., Huang, Z. J., and Siegelbaum, S.A. (2013)  A cortico-hippocampal learning rule enhances information flow through the hippocampal circuit by shaping local inhibitory microcircuit activity. Neuron 79 (6) 1208-1221. F1000 reviewed

Cover for NeuronpaperOn the cover:
Local circuits are driven by patterns of activity from distant brain regions. Long-term plastic changes in the excitatory and inhibitory synapses comprising these circuits may aid in encoding of salient information. Here, Basu et al. (pages 1208–1221) show that temporally precise cortico-hippocampal activity boosts excitatory transmission within the hippocampus by suppressing a powerful local inhibition mediated by interneurons that express cholecystokinin (CCK). This image, inspired by Gustav Klimt's “The Kiss,” depicts the embrace of a pair of lined seahorses (Hippocampus erectus; original image courtesy National Aquarium ©; obtained with permission from aqua.org) on a grassy CA1 field of the hippocampus, where a pyramidal neuron is nestled amongst CCK interneurons. This cover, “The Exciting Kiss of Suppressed Inhibition” (created by Jayeeta Basu entitled by Steven Siegelbaum), symbolizes the intimate interplay of hippocampal excitation and inhibition.

Basu, J., Betz, A., Brose, N., and Rosenmund, C. (2007) Munc13-1 C1 domain activation lowers the energy barrier for synaptic vesicle fusion. Journal of Neuroscience 27, 1200-1210  

Schluter, O. M., Basu, J., Sudhof, T. C., and Rosenmund, C. (2006) Rab3 superprimes synaptic vesicles for release: implications for short-term synaptic plasticity. Journal of Neuroscience 26, 1239-1246

Kalla, S., Stern, M., Basu, J., Varoqueaux, F., Reim, K., Rosenmund, C., Ziv, N. E., and Brose, N. (2006) Molecular dynamics of a presynaptic active zone protein studied in Munc13-1-enhanced yellow fluorescent protein knock-in mutant mice. Journal of Neuroscience 26, 13054-13066

Basu, J., Shen, N., Dulubova, I., Lu, J., Guan, R., Guryev, O., Grishin, N. V., Rosenmund, C., and Rizo, J. (2005) A minimal domain responsible for Munc13 activity. Nature Structural Molecular Biology 12, 1017-1018 . F1000 Reviewed

Reviews, Books and Book Chapters

Zemla, R and Basu, J. (2017) “Hippocampal Function in Rodents.” Neurobiology of Learning and Plasticity, Current Opinion in Neurobiology 2017, 43:187–197

Basu, J. and S. A. Siegelbaum (2015). The Corticohippocampal Circuit, Synaptic Plasticity, and Memory. Cold Spring Harb Perspect Biol 7(11)