Jessica E. Treisman, PhD

Professor; Skirball Institute of Biomolecular Medicine, Coord Developmental Genetics Program. Department of Cell Biology

LAB WEBSITE:
Treisman Lab

RESEARCH THEMES:
Cell Biology

 

 

 

Contact Information

540 First Avenue
Skirball Institute of Biomolecular Medicine
Floor 4, Lab 9
New York, NY 10016

Office Tel: 212-263-1031
Lab Tel: 212-263-1032
Fax: 212-263-7760
Email: jessica.treisman@med.nyu.edu

Admin Contact

Theresa Walton
Tel: 212-263-7595
Email: theresa.walton@med.nyu.edu

Cell Communication in Drosophila Visual System Development

Cells must communicate with each other during development to determine their positions within the organism and to take on the appropriate fates. The Drosophila visual system is a useful model system in which to examine how this communication occurs. Mutations that disrupt the ordered pattern of photoreceptor differentiation are easy to identify and have led us to uncover some unexpected signaling mechanisms. We currently work on lipid modifications of secreted signaling proteins, trafficking and endocytosis of receptors and ligands, and the regulation of protein stability. We are also interested in chromatin-based mechanisms in the transcriptional and post-transcriptional control of gene expression. In addition to cell fate choices, we study how neurons interact with each other to choose the correct synaptic partners. We use both the adult color-sensitive photoreceptors and the larval motor neurons to investigate the molecular mechanisms that allow synapses to form in the correct locations and to change over time.