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Alejandro Pironti

Alejandro Pironti, ScD

Assistant Professor, Department of Microbiology

Positions

Assistant Professor, Department of Microbiology at NYU Grossman School of Medicine

Director, Microbial Computational Genomic Core Lab

Graduate Education

ScD from Saarland University

Postdoctoral Training

Broad Institute of MIT and Harvard, Infectious Disease and Microbiome Program

Lab Website
Pironti Lab
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Academic office

430 East 29th Street, Alexandria – West Tower

5th floor

New York, NY 10016

Staphylococcus aureus senses human neutrophils via PerR to coordinate the expression of the toxin LukAB

Savin, Avital; Anderson, Exene E; Dyzenhaus, Sophie; Podkowik, Magdalena; Shopsin, Bo; Pironti, Alejandro; Torres, Victor J

Infection & immunity. 2024 Feb 13; 92(2):e0052623

Unlatching of the stem domains in the Staphylococcus aureus pore-forming leukocidin LukAB influences toxin oligomerization

Ilmain, Juliana K; Perelman, Sofya S; Panepinto, Maria C; Irnov, Irnov; Coudray, Nicolas; Samhadaneh, Nora; Pironti, Alejandro; Ueberheide, Beatrix; Ekiert, Damian C; Bhabha, Gira; Torres, Victor J

Journal of biological chemistry. 2023 Dec; 299(12):105321

Longitudinal gut microbiome analyses and blooms of pathogenic strains during lupus disease flares

Azzouz, Doua F; Chen, Ze; Izmirly, Peter M; Chen, Lea Ann; Li, Zhi; Zhang, Chongda; Mieles, David; Trujillo, Kate; Heguy, Adriana; Pironti, Alejandro; Putzel, Greg G; Schwudke, Dominik; Fenyo, David; Buyon, Jill P; Alekseyenko, Alexander V; Gisch, Nicolas; Silverman, Gregg J

Annals of the rheumatic diseases. 2023 Oct; 82(10):1315-1327

Antimicrobial overproduction sustains intestinal inflammation by inhibiting Enterococcus colonization

Jang, Kyung Ku; Heaney, Thomas; London, Mariya; Ding, Yi; Putzel, Gregory; Yeung, Frank; Ercelen, Defne; Chen, Ying-Han; Axelrad, Jordan; Gurunathan, Sakteesh; Zhou, Chaoting; Podkowik, Magdalena; Arguelles, Natalia; Srivastava, Anusha; Shopsin, Bo; Torres, Victor J; Keestra-Gounder, A Marijke; Pironti, Alejandro; Griffin, Matthew E; Hang, Howard C; Cadwell, Ken

Cell host & microbe. 2023 Sep 13; 31(9):1450-1468.e8

Effects of Capsular Polysaccharide amount on Pneumococcal-Host interactions

Zhu, Jiaqi; Abruzzo, Annie R; Wu, Cindy; Bee, Gavyn Chern Wei; Pironti, Alejandro; Putzel, Gregory; Aggarwal, Surya D; Eichner, Hannes; Weiser, Jeffrey N

PLoS pathogens. 2023 Aug; 19(8):e1011509

Aldehyde accumulation in Mycobacterium tuberculosis with defective proteasomal degradation results in copper sensitivity

Limón, Gina; Samhadaneh, Nora M; Pironti, Alejandro; Darwin, K Heran

MBio. 2023 Jun 23; e0036323

Capsular Polysaccharide Is Essential for the Virulence of the Antimicrobial-Resistant Pathogen Enterobacter hormaechei

St John, Amelia; Perault, Andrew I; Giacometti, Sabrina I; Sommerfield, Alexis G; DuMont, Ashley L; Lacey, Keenan A; Zheng, Xuhui; Sproch, Julia; Petzold, Chris; Dancel-Manning, Kristen; Gonzalez, Sandra; Annavajhala, Medini; Beckford, Colleen; Zeitouni, Nathalie; Liang, Feng-Xia; van Bakel, Harm; Shopsin, Bo; Uhlemann, Anne-Catrin; Pironti, Alejandro; Torres, Victor J

MBio. 2023 Feb 13; e0259022

Clostridia isolated from helminth-colonized humans promote the life cycle of Trichuris species

Sargsian, Shushan; Chen, Ze; Lee, Soo Ching; Robertson, Amicha; Thur, Rafaela Saes; Sproch, Julia; Devlin, Joseph C; Tee, Mian Zi; Er, Yi Xian; Copin, Richard; Heguy, Adriana; Pironti, Alejandro; Torres, Victor J; Ruggles, Kelly V; Lim, Yvonne A L; Bethony, Jeffrey; Loke, P'ng; Cadwell, Ken

Cell reports. 2022 Nov 29; 41(9):111725

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