Ana Rodriguez

Ana Rodriguez, PhD

Associate Professor, Department of Microbiology

Keywords
malaria, inflammation, Plasmodium, cerebral malaria, severe anemia, immunology, microbiology
Summary

Our lab studies two different parasites, Plasmodium, which causes Malaria and Trypanosoma cruzi, which causes Chagas disease. Malaria is a devastating disease that causes about 400,000 deaths per year, mainly among children in Africa. There is an urgent need for new strategies to control malaria, but there is a lack of detailed knowledge of the basic biological processes of Plasmodium, that would allow faster development of anti-malaria drugs and vaccines. A main interest of our laboratory is the study of malaria-induced inflammatory pathology and its implications in the pathology of disease, including cerebral malaria and severe anemia. We also intend to develop effective drugs against Chagas Disease. In collaboration with GSK, we have performed high through put screenings of intracellular Trypanosoma cruzi, to find compounds with anti-trypanosomal activities. Selected compounds are being tested for efficacy in mice.

http://www.med.nyu.edu/microbiology-parasitology/faculty/rodriguez-lab-microbiology

Phone

212-263-6757

Academic office

341 East 25th Street

New York, NY 10010

Lab Website
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Associate Professor, Department of Microbiology

Co-Director, Anopheles Insectary

PhD from Autonomous University of Madrid

Fellowship, Institute Curie, Paris, France, Cell Biology/Immunology

Fellowship, Yale University School of Medicine, Cell Biology/Parasitology

Gallego-Delgado, Julio; Rodriguez, Ana

Frontiers in cellular & infection microbiology. 2014; 4:121-121

Lee, Seung Ah; Erath, Jessey; Zheng, Guoan; Ou, Xiaoze; Willems, Phil; Eichinger, Daniel; Rodriguez, Ana; Yang, Changhuei

PLoS one. 2014; 9(2):e89712-e89712e89712

Dandapani, Sivaraman; Germain, Andrew R; Jewett, Ivan; le Quement, Sebastian; Marie, Jean-Charles; Muncipinto, Giovanni; Duvall, Jeremy R; Carmody, Leigh C; Perez, Jose R; Engel, Juan C; Gut, Jiri; Kellar, Danielle; Siqueira-Neto, Jair Lage; McKerrow, James H; Kaiser, Marcel; Rodriguez, Ana; Palmer, Michelle A; Foley, Michael; Schreiber, Stuart L; Munoz, Benito

ACS medicinal chemistry letters. 2014 Feb 13; 5(2):149-153

Assembling new chemical boxes as an open source of starting points for drug discovery against kinetoplastid parasites causing neglected tropical diseases [Meeting Abstract]

Martin, J J; Alvarez, E; Bardera, A I; Cantizani, J; Colmenarejo, G; Fiandor, J M; Kessler, A; Manzano, M P; Alonso-Padilla, J; Pena, I; Rodriguez, A

American journal of tropical medicine & hygiene. 2014 Nov; 91(5):591-591

Gallego-Delgado, Julio; Rodriguez, Ana

Trends in parasitology. 2017 Jul 11; ?-?

Dawidowski, M; Emmanouilidis, L; Kalel, V C; Tripsianes, K; Schorpp, K; Hadian, K; Kaiser, M; Maser, P; Kolonko, M; Tanghe, S; Rodriguez, A; Schliebs, W; Erdmann, R; Sattler, M; Popowicz, G M

Science. 2017 Mar 31; 355(6332):1416-1420

Devine, William; Thomas, Sarah M; Erath, Jessey; Bachovchin, Kelly A; Lee, Patricia J; Leed, Susan E; Rodriguez, Ana; Sciotti, Richard J; Mensa-Wilmot, Kojo; Pollastri, Michael P

ACS medicinal chemistry letters. 2017 Mar 09; 8(3):350-354

Russell, Stephanie; Rahmani, Raphael; Jones, Amy J; Newson, Harriet L; Neilde, Kevin; Cotillo, Ignacio; Rahmani Khajouei, Marzieh; Ferrins, Lori; Qureishi, Sana; Nguyen, Nghi; Martinez-Martinez, Maria S; Weaver, Donald F; Kaiser, Marcel; Riley, Jennifer; Thomas, John; De Rycker, Manu; Read, Kevin D; Flematti, Gavin R; Ryan, Eileen; Tanghe, Scott; Rodriguez, Ana; Charman, Susan A; Kessler, Albane; Avery, Vicky M; Baell, Jonathan B; Piggott, Matthew J

Journal of medicinal chemistry. 2016 Nov 10; 59(21):9686-9720