Ana Rodriguez

Ana Rodriguez, PhD

Associate Professor, Department of Microbiology

Keywords
malaria, inflammation, Plasmodium, cerebral malaria, severe anemia, immunology, microbiology
Summary

Our lab studies two different parasites, Plasmodium, which causes Malaria and Trypanosoma cruzi, which causes Chagas disease. Malaria is a devastating disease that causes about 400,000 deaths per year, mainly among children in Africa. There is an urgent need for new strategies to control malaria, but there is a lack of detailed knowledge of the basic biological processes of Plasmodium, that would allow faster development of anti-malaria drugs and vaccines. A main interest of our laboratory is the study of malaria-induced inflammatory pathology and its implications in the pathology of disease, including cerebral malaria and severe anemia. We also intend to develop effective drugs against Chagas Disease. In collaboration with GSK, we have performed high through put screenings of intracellular Trypanosoma cruzi, to find compounds with anti-trypanosomal activities. Selected compounds are being tested for efficacy in mice.

http://www.med.nyu.edu/microbiology-parasitology/faculty/rodriguez-lab-microbiology

Phone

646-501-6997

Academic office

430 E. 29th st, Alexandria Center West Tower

room 511, lab 524

New York, NY 10010

Lab Website
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Associate Professor, Department of Microbiology

Co-Director, Anopheles Insectary

PhD from Autonomous University of Madrid

Fellowship, Institute Curie, Paris, France, Cell Biology/Immunology

Fellowship, Yale University School of Medicine, Cell Biology/Parasitology

Fernandez-Arias, Cristina; Rivera-Correa, Juan; Gallego-Delgado, Julio; Rudlaff, Rachel; Fernandez, Clemente; Roussel, Camille; Gotz, Anton; Gonzalez, Sandra; Mohanty, Akshaya; Mohanty, Sanjib; Wassmer, Samuel; Buffet, Pierre; Ndour, Papa Alioune; Rodriguez, Ana

Cell host & microbe. 2016 Feb 10; 19(2):194-203

Gallego-Delgado, Julio; Basu-Roy, Upal; Ty, Maureen; Alique, Matilde; Fernandez-Arias, Cristina; Movila, Alexandru; Gomes, Pollyanna; Weinstock, Ada; Xu, Wenyue; Edagha, Innocent; Wassmer, Samuel C; Walther, Thomas; Ruiz-Ortega, Marta; Rodriguez, Ana

Journal of clinical investigation. 2016 Oct 03; 126(10):4016-4029

Gotz, Anton; Tang, Mei San; Ty, Maureen C; Arama, Charles; Ongoiba, Aissata; Doumtabe, Didier; Traore, Boubacar; Crompton, Peter D; Loke, P'ng; Rodriguez, Ana

Proceedings of the National Academy of Sciences of the United States of America (PNAS). 2017 Nov 21; 114(49):E10568-E10577

Rivera-Correa, J; Guthmiller, J J; Vijay, R; Fernandez-Arias, C; Pardo-Ruge, M A; Gonzalez, S; Butler, N S; Rodriguez, A

Nature communications. 2017 Nov 03; 8(1):1282-1282

Orengo, Jamie M; Evans, James E; Bettiol, Esther; Leliwa-Sytek, Aleksandra; Day, Karen; Rodriguez, Ana

PLoS pathogens. 2008 Mar 07; 4(3):e1000013-e1000013

Ocana-Morgner, Carlos; Mota, Maria M; Rodriguez, Ana

Journal of experimental medicine. 2003 Jan 20; 197(2):143-151

Mota, Maria M; Hafalla, Julius C R; Rodriguez, Ana

Nature medicine. 2002 Nov; 8(11):1318-1322

Mota MM; Pradel G; Vanderberg JP; Hafalla JC; Frevert U; Nussenzweig RS; Nussenzweig V; Rodriguez A

Science. 2001 Jan 05; 291(5501):141-144

Drug May Prevent Bleeding in Malaria-Infected Brains