Beatrix M. Ueberheide

Beatrix M. Ueberheide, PhD

Assistant Professor, Department of Biochemistry and Molecular Pharmacology

pharmacology, proteomics, biological mass spectrometry, de novo sequencing

Dr. Ueberheide joined the faculty of NYU as the Director of the Proteomics Core. She will be establishing a fully integrated state of the art mass spectrometry laboratory focusing on proteomics. She has extensive experience in biological mass spectrometry especially method development, mapping of post translational modifications, de novo sequencing, Bottom Up and Top Down strategies, as well as comprehensive protein characterization in complex mixtures. Dr. Ueberheide contributed to a wide range of studies from analyzing chromatin, characterizing venoms, to sequencing of complex antibody mixtures. She received her PhD in chemistry at the University of Virginia where she focused on the study of histone post translational modifications using classical Bottom Up and also Top Down strategies. She joined Rockefeller University in 2006 for her postdoctoral training. There she developed de novo sequencing strategies for analysis of venom components and established techniques to study antibodies isolated from HIV infected long-term non-progressors. In her role as the director of proteomics she will enable the NYU faculty in their research efforts of understanding cellular function by characterizing proteins in a biological context. The current focus of her research is to develop advanced mass- spectrometry based techniques to characterize circulating antibodies and to understand the structure-function relationship of peptide toxins. She utilizes chemical strategies in combination with electron transfer dissociation to increase the biological relevant information obtained from mass spectrometric data.



Academic office

430 East 29th Street, Alexandria Bldg. East

8, 860

New York, NY 10016

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These focus areas and their associated publications are derived from medical subject headings from PubMed.
represents one publication

Assistant Professor, Department of Biochemistry and Molecular Pharmacology

Director, Proteomics Resource Center

PhD from University of Virginia

Diamond, Julie M; Vanpouille-Box, Claire; Spada, Sheila; Rudqvist, Nils-Petter; Chapman, Jessica; Ueberheide, Beatrix; Pilones, Karsten A; Sarfraz, Yasmeen; Formenti, Silvia C; Demaria, Sandra

Cancer immunology research. 2018 Aug 17; 6(8):910-920

de la Parra, Columba; Ernlund, Amanda; Alard, Amandine; Ruggles, Kelly; Ueberheide, Beatrix; Schneider, Robert J

Nature communications. 2018 Aug 03; 9(1):3068-3068

Pelzek, Adam J; Shopsin, Bo; Radke, Emily E; Tam, Kayan; Ueberheide, Beatrix M; Fenyö, David; Brown, Stuart M; Li, Qianhao; Rubin, Ada; Fulmer, Yi; Chiang, William K; Hernandez, David N; El Bannoudi, Hanane; Sause, William E; Sommerfield, Alexis; Thomsen, Isaac P; Miller, Andy O; Torres, Victor J; Silverman, Gregg J

MBio. 2018 Mar 13; 9(2):

Human memory B cells targeting Staphylococcus aureus exotoxins are prevalent with skin and soft tissue infection

Pelzek, A J; Shopsin, B; Radke, E E; Tam, K; Ueberheide, B M; Fenyo, D; Brown, S M; Li, Q; Rubin, A; Fulmer, Y; Chiang, W K; Hernandez, D N; El, Bannoudi H; Sause, W E; Sommerfield, A; Thomsen, I P; Miller, A O; Torres, V J; Silverman, G J

MBio. 2018 March-April; 9(2):

Harper, Lamia; Balasubramanian, Divya; Ohneck, Elizabeth A; Sause, William E; Chapman, Jessica; Mejia-Sosa, Bryan; Lhakhang, Tenzin; Heguy, Adriana; Tsirigos, Aristotelis; Ueberheide, Beatrix; Boyd, Jeffrey M; Lun, Desmond S; Torres, Victor J

MBio. 2018 Jan 23; 9(1):

Mita, Paolo; Wudzinska, Aleksandra; Sun, Xiaoji; Andrade, Joshua; Nayak, Shruti; Kahler, David J; Badri, Sana; LaCava, John; Ueberheide, Beatrix; Yun, Chi Y; Fenyo, David; Boeke, Jef D

eLife. 2018 Jan 08; 7:

Drummond, Eleanor; Nayak, Shruti; Pires, Geoffrey; Ueberheide, Beatrix; Wisniewski, Thomas

Methods in molecular biology. 2018 01; 1723:319-334

Peled, Michael; Tocheva, Anna S; Sandigursky, Sabina; Nayak, Shruti; Philips, Elliot A; Nichols, Kim E; Strazza, Marianne; Azoulay-Alfaguter, Inbar; Askenazi, Manor; Neel, Benjamin G; Pelzek, Adam J; Ueberheide, Beatrix; Mor, Adam

Proceedings of the National Academy of Sciences of the United States of America (PNAS). 2017 Dec 27; 115(3):E468-E477