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Beatrix M. Ueberheide

Beatrix M. Ueberheide, PhD

Associate Professor, Department of Biochemistry and Molecular Pharmacology

Associate Professor, Department of Neurology

pharmacology, proteomics, biological mass spectrometry, de novo sequencing

Dr. Ueberheide joined the faculty of NYU as the Director of the Proteomics Core. She will be establishing a fully integrated state of the art mass spectrometry laboratory focusing on proteomics. She has extensive experience in biological mass spectrometry especially method development, mapping of post translational modifications, de novo sequencing, Bottom Up and Top Down strategies, as well as comprehensive protein characterization in complex mixtures. Dr. Ueberheide contributed to a wide range of studies from analyzing chromatin, characterizing venoms, to sequencing of complex antibody mixtures. She received her PhD in chemistry at the University of Virginia where she focused on the study of histone post translational modifications using classical Bottom Up and also Top Down strategies. She joined Rockefeller University in 2006 for her postdoctoral training. There she developed de novo sequencing strategies for analysis of venom components and established techniques to study antibodies isolated from HIV infected long-term non-progressors. In her role as the director of proteomics she will enable the NYU faculty in their research efforts of understanding cellular function by characterizing proteins in a biological context. The current focus of her research is to develop advanced mass- spectrometry based techniques to characterize circulating antibodies and to understand the structure-function relationship of peptide toxins. She utilizes chemical strategies in combination with electron transfer dissociation to increase the biological relevant information obtained from mass spectrometric data.



Academic office

430 East 29th Street, Alexandria Bldg. East

8, 860

New York, NY 10016

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These focus areas and their associated publications are derived from medical subject headings from PubMed.
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PhD from University of Virginia

Thierry, Manon; Ponce, Jackeline; Martà-Ariza, Mitchell; Askenazi, Manor; Faustin, Arline; Leitner, Dominique; Pires, Geoffrey; Kanshin, Evgeny; Drummond, Eleanor; Ueberheide, Beatrix; Wisniewski, Thomas

Acta neuropathologica. 2024 May 21; 147(1):91

Rona, Gergely; Miwatani-Minter, Bearach; Zhang, Qingyue; Goldberg, Hailey V; Kerzhnerman, Marc A; Howard, Jesse B; Simoneschi, Daniele; Lane, Ethan; Hobbs, John W; Sassani, Elizabeth; Wang, Andrew A; Keegan, Sarah; Laverty, Daniel J; Piett, Cortt G; Pongor, Lorinc S; Xu, Miranda Li; Andrade, Joshua; Thomas, Anish; Sicinski, Piotr; Askenazi, Manor; Ueberheide, Beatrix; Fenyö, David; Nagel, Zachary D; Pagano, Michele

Molecular cell. 2024 Apr 04; 84(7):1224-1242.e13

Jaisinghani, Neetika; Previti, Mary L; Andrade, Joshua; Askenazi, Manor; Ueberheide, Beatrix; Seeliger, Jessica C

Cell chemical biology. 2024 Mar 21; 31(3):523-533.e4

Neves, Jorge L B; Urcino, Cristoval; Chase, Kevin; Dowell, Cheryl; Hone, Arik J; Morgenstern, David; Chua, Victor M; Ramiro, Iris Bea L; Imperial, Julita S; Leavitt, Lee S; Phan, Jasmine; Fisher, Fernando A; Watkins, Maren; Raghuraman, Shrinivasan; Tun, Jortan O; Ueberheide, Beatrix M; McIntosh, J Michael; Vasconcelos, Vitor; Olivera, Baldomero M; Gajewiak, Joanna

Marine drugs. 2024 Feb 29; 22(3):

Leitner, Dominique; Pires, Geoffrey; Kavanagh, Tomas; Kanshin, Evgeny; Askenazi, Manor; Ueberheide, Beatrix; Devinsky, Orrin; Wisniewski, Thomas; Drummond, Eleanor

Acta neuropathologica. 2024 Jan 30; 147(1):27

Chapman, Jessica R; Paukner, Max; Leser, Micheal; Teng, Kai Wen; Koide, Shohei; Holder, Marlene; Armache, Karim-Jean; Becker, Chris; Ueberheide, Beatrix; Brenowitz, Michael

Analytical chemistry. 2023 Dec 19; 95(50):18316-18325

Ilmain, Juliana K; Perelman, Sofya S; Panepinto, Maria C; Irnov, Irnov; Coudray, Nicolas; Samhadaneh, Nora; Pironti, Alejandro; Ueberheide, Beatrix; Ekiert, Damian C; Bhabha, Gira; Torres, Victor J

Journal of biological chemistry. 2023 Dec; 299(12):105321

Hegelmeyer, Nuri K; Parkin, Lia A; Previti, Mary L; Andrade, Joshua; Utama, Raditya; Sejour, Richard J; Gardin, Justin; Muller, Stephanie; Ketchum, Steven; Yurovsky, Alisa; Futcher, Bruce; Goodwin, Sara; Ueberheide, Beatrix; Seeliger, Jessica C

MBio. 2023 Oct 31; 14(5):e0084123