Beatrix M. Ueberheide

Beatrix M. Ueberheide, PhD

Assistant Professor, Department of Biochemistry and Molecular Pharmacology

pharmacology, proteomics, biological mass spectrometry, de novo sequencing

Dr. Ueberheide joined the faculty of NYU as the Director of the Proteomics Core. She will be establishing a fully integrated state of the art mass spectrometry laboratory focusing on proteomics. She has extensive experience in biological mass spectrometry especially method development, mapping of post translational modifications, de novo sequencing, Bottom Up and Top Down strategies, as well as comprehensive protein characterization in complex mixtures. Dr. Ueberheide contributed to a wide range of studies from analyzing chromatin, characterizing venoms, to sequencing of complex antibody mixtures. She received her PhD in chemistry at the University of Virginia where she focused on the study of histone post translational modifications using classical Bottom Up and also Top Down strategies. She joined Rockefeller University in 2006 for her postdoctoral training. There she developed de novo sequencing strategies for analysis of venom components and established techniques to study antibodies isolated from HIV infected long-term non-progressors. In her role as the director of proteomics she will enable the NYU faculty in their research efforts of understanding cellular function by characterizing proteins in a biological context. The current focus of her research is to develop advanced mass- spectrometry based techniques to characterize circulating antibodies and to understand the structure-function relationship of peptide toxins. She utilizes chemical strategies in combination with electron transfer dissociation to increase the biological relevant information obtained from mass spectrometric data.



Academic office

430 East 29th Street, Alexandria Bldg. East

8, 860

New York, NY 10016

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These focus areas and their associated publications are derived from medical subject headings from PubMed.
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Assistant Professor, Department of Biochemistry and Molecular Pharmacology

Director, Proteomics Resource Center

PhD from University of Virginia

Vasudevan, Deepika; Clark, Nicholas K; Sam, Jessica; Cotham, Victoria C; Ueberheide, Beatrix; Marr, Michael T 2nd; Ryoo, Hyung Don

Cell reports. 2017 Nov 21; 21(8):2039-2047

Moretti, Julien; Roy, Soumit; Bozec, Dominique; Martinez, Jennifer; Chapman, Jessica R; Ueberheide, Beatrix; Lamming, Dudley W; Chen, Zhijian J; Horng, Tiffany; Yeretssian, Garabet; Green, Douglas R; Blander, J Magarian

Cell. 2017 Oct 19; 171(4):809-823.e13

Robinson, Samuel D; Undheim, Eivind Ab; Ueberheide, Beatrix; King, Glenn F

Expert review of proteomics. 2017 Sep 13; 14(10):931-939

Kim, KyeongJin; Ryu, Dongryeol; Dongiovanni, Paola; Ozcan, Lale; Nayak, Shruti; Ueberheide, Beatrix; Valenti, Luca; Auwerx, Johan; Pajvani, Utpal B

Gastroenterology. 2017 Aug 30; 153(6):1568-1580.e10

Agrawal, Praveen; Fontanals-Cirera, Barbara; Sokolova, Elena; Jacob, Samson; Vaiana, Christopher A; Argibay, Diana; Davalos, Veronica; McDermott, Meagan; Nayak, Shruti; Darvishian, Farbod; Castillo, Mireia; Ueberheide, Beatrix; Osman, Iman; Fenyo, David; Mahal, Lara K; Hernando, Eva

Cancer cell. 2017 Jun 12; 31(6):804-819.e7

Chirco, Kathleen R; Worthington, Kristan S; Flamme-Wiese, Miles J; Riker, Megan J; Andrade, Joshua D; Ueberheide, Beatrix M; Stone, Edwin M; Tucker, Budd A; Mullins, Robert F

Acta biomaterialia. 2017 May 5; 57:293-303

Coleman, Kate E; Bekes, Miklos; Chapman, Jessica R; Crist, Sarah B; Jones, Mathew Jk; Ueberheide, Beatrix M; Huang, Tony T

eLife. 2017 May 5; 6:?-?

Daley, Donnele; Mani, Vishnu R; Mohan, Navyatha; Akkad, Neha; Ochi, Atsuo; Heindel, Daniel W; Lee, Ki Buom; Zambirinis, Constantinos P; Pandian, Gautam Sd Balasubramania; Savadkar, Shivraj; Torres-Hernandez, Alejandro; Nayak, Shruti; Wang, Ding; Hundeyin, Mautin; Diskin, Brian; Aykut, Berk; Werba, Gregor; Barilla, Rocky M; Rodriguez, Robert; Chang, Steven; Gardner, Lawrence; Mahal, Lara K; Ueberheide, Beatrix; Miller, George

Nature medicine. 2017 Apr 10; 23(5):556-567