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Beatrix M. Ueberheide

Beatrix M. Ueberheide, PhD

Associate Professor, Department of Biochemistry and Molecular Pharmacology

Associate Professor, Department of Neurology

pharmacology, proteomics, biological mass spectrometry, de novo sequencing

Dr. Ueberheide joined the faculty of NYU as the Director of the Proteomics Core. She will be establishing a fully integrated state of the art mass spectrometry laboratory focusing on proteomics. She has extensive experience in biological mass spectrometry especially method development, mapping of post translational modifications, de novo sequencing, Bottom Up and Top Down strategies, as well as comprehensive protein characterization in complex mixtures. Dr. Ueberheide contributed to a wide range of studies from analyzing chromatin, characterizing venoms, to sequencing of complex antibody mixtures. She received her PhD in chemistry at the University of Virginia where she focused on the study of histone post translational modifications using classical Bottom Up and also Top Down strategies. She joined Rockefeller University in 2006 for her postdoctoral training. There she developed de novo sequencing strategies for analysis of venom components and established techniques to study antibodies isolated from HIV infected long-term non-progressors. In her role as the director of proteomics she will enable the NYU faculty in their research efforts of understanding cellular function by characterizing proteins in a biological context. The current focus of her research is to develop advanced mass- spectrometry based techniques to characterize circulating antibodies and to understand the structure-function relationship of peptide toxins. She utilizes chemical strategies in combination with electron transfer dissociation to increase the biological relevant information obtained from mass spectrometric data.



Academic office

430 East 29th Street, Alexandria Bldg. East

8, 860

New York, NY 10016

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These focus areas and their associated publications are derived from medical subject headings from PubMed.
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PhD from University of Virginia

Mena, Elijah L; Donahue, Callie J; Vaites, Laura Pontano; Li, Jie; Rona, Gergely; O'Leary, Colin; Lignitto, Luca; Miwatani-Minter, Bearach; Paulo, Joao A; Dhabaria, Avantika; Ueberheide, Beatrix; Gygi, Steven P; Pagano, Michele; Harper, J Wade; Davey, Robert A; Elledge, Stephen J

Proceedings of the National Academy of Sciences of the United States of America (PNAS). 2021 04 27; 118(17):

Strazza, Marianne; Adam, Kieran; Lerrer, Shalom; Straube, Johanna; Sandigursky, Sabina; Ueberheide, Beatrix; Mor, Adam

Inflammation. 2021 Feb 24;

Miles, Madeleine R; Seo, John; Jiang, Min; Wilson, Zachary T; Little, Janay; Hao, Jon; Andrade, Joshua; Ueberheide, Beatrix; Tseng, Gea-Ny

Journal of molecular & cellular cardiology. 2021 Feb 23; 155:1-9

Lahiri, Tanaya; Brambilla, Lara; Andrade, Joshua; Askenazi, Manor; Ueberheide, Beatrix; Levy, David E

Molecular oncology. 2021 Feb 18;

Ledet, Russell J; Ruff, Sophie E; Wang, Yu; Nayak, Shruti; Schneider, Jeffrey A; Ueberheide, Beatrix; Logan, Susan K; Garabedian, Michael J

Communications biology. 2021 Jan 04; 4(1):36

Tocheva, Anna S; Peled, Michael; Strazza, Marianne; Adam, Kieran R; Lerrer, Shalom; Nayak, Shruti; Azoulay-Alfaguter, Inbar; Foster, Connor J R; Philips, Elliot A; Neel, Benjamin; Ueberheide, Beatrix; Mor, Adam

Journal of biological chemistry. 2020 Dec 25; 295(52):18036-18050

Jolly, Samson M; Gainetdinov, Ildar; Jouravleva, Karina; Zhang, Han; Strittmatter, Lara; Bailey, Shannon M; Hendricks, Gregory M; Dhabaria, Avantika; Ueberheide, Beatrix; Zamore, Phillip D

Cell. 2020 Sep 17; 182(6):1545-1559.e18

Drummond, Eleanor; Pires, Geoffrey; MacMurray, Claire; Askenazi, Manor; Nayak, Shruti; Bourdon, Marie; Safar, Jiri; Ueberheide, Beatrix; Wisniewski, Thomas

Brain. 2020 Sep 01; 143(9):2803-2817