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Beatrix M. Ueberheide

Beatrix M. Ueberheide, PhD

Associate Professor, Department of Biochemistry and Molecular Pharmacology

Associate Professor, Department of Neurology

pharmacology, proteomics, biological mass spectrometry, de novo sequencing

Dr. Ueberheide joined the faculty of NYU as the Director of the Proteomics Core. She will be establishing a fully integrated state of the art mass spectrometry laboratory focusing on proteomics. She has extensive experience in biological mass spectrometry especially method development, mapping of post translational modifications, de novo sequencing, Bottom Up and Top Down strategies, as well as comprehensive protein characterization in complex mixtures. Dr. Ueberheide contributed to a wide range of studies from analyzing chromatin, characterizing venoms, to sequencing of complex antibody mixtures. She received her PhD in chemistry at the University of Virginia where she focused on the study of histone post translational modifications using classical Bottom Up and also Top Down strategies. She joined Rockefeller University in 2006 for her postdoctoral training. There she developed de novo sequencing strategies for analysis of venom components and established techniques to study antibodies isolated from HIV infected long-term non-progressors. In her role as the director of proteomics she will enable the NYU faculty in their research efforts of understanding cellular function by characterizing proteins in a biological context. The current focus of her research is to develop advanced mass- spectrometry based techniques to characterize circulating antibodies and to understand the structure-function relationship of peptide toxins. She utilizes chemical strategies in combination with electron transfer dissociation to increase the biological relevant information obtained from mass spectrometric data.



Academic office

430 East 29th Street, Alexandria Bldg. East

8, 860

New York, NY 10016

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These focus areas and their associated publications are derived from medical subject headings from PubMed.
represents one publication
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PhD from University of Virginia

Leitner, Dominique F; Siu, Yik; Korman, Aryeh; Lin, Ziyan; Kanshin, Evgeny; Friedman, Daniel; Devore, Sasha; Ueberheide, Beatrix; Tsirigos, Aristotelis; Jones, Drew R; Wisniewski, Thomas; Devinsky, Orrin

Epilepsia. 2023 Apr; 64(4):1046-1060

Leitner, Dominique F; Lin, Ziyan; Sawaged, Zacharia; Kanshin, Evgeny; Friedman, Daniel; Devore, Sasha; Ueberheide, Beatrix; Chang, Julia W; Mathern, Gary W; Anink, Jasper J; Aronica, Eleonora; Wisniewski, Thomas; Devinsky, Orrin

Epilepsia. 2023 Jan; 64(1):218-230

Pires, Geoffrey; Ueberheide, Beatrix; Wisniewski, Thomas; Drummond, Eleanor

Methods in molecular biology. 2023 Nov; 2561:263-277

Cavers, Ann; Kugler, Matthias Christian; Ozguler, Yesim; Al-Obeidi, Arshed Fahad; Hatemi, Gulen; Ueberheide, Beatrix M; Ucar, Didar; Manches, Olivier; Nowatzky, Johannes

Annals of the rheumatic diseases. 2022 Nov; 81:1603-1611

Matsuzawa-Ishimoto, Yu; Yao, Xiaomin; Koide, Akiko; Ueberheide, Beatrix M; Axelrad, Jordan E; Reis, Bernardo S; Parsa, Roham; Neil, Jessica A; Devlin, Joseph C; Rudensky, Eugene; Dewan, M Zahidunnabi; Cammer, Michael; Blumberg, Richard S; Ding, Yi; Ruggles, Kelly V; Mucida, Daniel; Koide, Shohei; Cadwell, Ken

Nature. 2022 10; 610(7932):547-554

Hosfelt, Jordan; Richards, Aweon; Zheng, Meng; Adura, Carolina; Nelson, Brock; Yang, Amy; Fay, Allison; Resager, William; Ueberheide, Beatrix; Glickman, J Fraser; Lupoli, Tania J

Cell chemical biology. 2022 May 19; 29(5):854-869.e9

Kleffman, Kevin; Levinson, Grace; Rose, Indigo V L; Blumenberg, Lili M; Shadaloey, Sorin A A; Dhabaria, Avantika; Wong, Eitan; Galan-Echevarria, Francisco; Karz, Alcida; Argibay, Diana; Von Itter, Richard; Floristan, Alfredo; Baptiste, Gillian; Eskow, Nicole M; Tranos, James A; Chen, Jenny; Vega Y Saenz de Miera, Eleazar C; Call, Melissa; Rogers, Robert; Jour, George; Wadghiri, Youssef Zaim; Osman, Iman; Li, Yue-Ming; Mathews, Paul; DeMattos, Ronald; Ueberheide, Beatrix; Ruggles, Kelly V; Liddelow, Shane A; Schneider, Robert J; Hernando, Eva

Cancer discovery. 2022 May 02; 12(5):1314-1335

Leitner, Dominique F; William, Christopher; Faustin, Arline; Askenazi, Manor; Kanshin, Evgeny; Snuderl, Matija; McGuone, Declan; Wisniewski, Thomas; Ueberheide, Beatrix; Gould, Laura; Devinsky, Orrin

Acta neuropathologica. 2022 May; 143(5):585-599