Adjunct Professor, Department of Medicine
My main interests are statin safety and intolerance and the effects of statins on cardiovascular disease. I have designed, conducted, and analyzed efficacy and safety data from large cardiovascular outcomes trials of statins in various populations, including patients with diabetes, stroke or transient ischemic attack (TIA), cardiovascular disease, and chronic kidney disease.
My research has involved the following:
In addition, I was a member of the steering committee of the Biochemical Efficacy and Safety Trial of Vitamin D, or BEST-D. This randomized double-blind trial in people older than 65 years evaluated the effects of one year of vitamin D treatment at either 4,000 IU or 2,000 IU per day, compared with placebo. Outcomes measured included levels of vitamin D, parathyroid hormone, and calcium; other safety parameters; and selected cardiovascular endpoints such as arterial stiffness, blood pressure, and lipids.
I am currently chair of the task force for the Endocrine Society’s clinical practice guideline on lipid management in patients with endocrine disorders, including type 1 and type 2 diabetes.
Previously, I studied mammary gland growth and development and the role of novel pituitary factors in primate and rodent models. My earlier clinical research focused on new therapies for the treatment of pituitary tumors, including the effects of somatostatin analogues in patients with acromegaly. I have also investigated the effects of growth hormone replacement on cardiopulmonary function in growth-hormone–deficient adults.
MD from Cornell University
Fellowship, Columbia University College of Physicians and Surgeons, Endocrinology and Metabolism
Residency, Beth Israel Medical Center, New York, NY, Internal Medicine
Journal of clinical endocrinology & metabolism. 2023 Mar 10; 108(4):784-790
Endocrinology & metabolism clinics of North America. 2022 Sep; 51(3):655-679
Diabetes research & clinical practice. 2022 Jul 03; 190:109980
Journal of women's health (Larchmont, N.Y. : 2002). 2022 Jul; 31(7):905-910
Current developments in nutrition. 2022 Jun; 6(6):nzac084
Best practice & research. Clinical endocrinology & metabolism. 2022 May 10; 101667
Journal of the National Medical Association. 2022 Feb; 114(1):42-46
Clinical therapeutics. 2022 Jan; 44(1):23-32