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Daniel Meruelo

Daniel Meruelo, PhD

Professor, Department of Pathology

Keywords
cancer, molecular, cellular, & translational neuroscience, gene therapy, Alzheimer's research
Summary

Our group is involved in the development of gene therapy vectors that can target and eradicate tumor cells in vivo, whether they be localized or spread throughout the body. We utilize state of the art approaches to achieve this goal, including in vivo imaging. Also we are engaged in studies of the high affinity laminin receptor, understanding its role in cancer, and its structure. Other efforts in the lab are directed at discovering novel therapeutic agents for viral diseases and neurological diseases such as Alzheimers.

Phone

212-263-5599

Academic office

550 First Avenue

5th Floor, MSB 507

New York, NY 10016

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These focus areas and their associated publications are derived from medical subject headings from PubMed.
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Positions

Professor, Department of Pathology at NYU Grossman School of Medicine

Director Gene Therapy Center

Graduate Education

PhD from Johns Hopkins University

Postdoctoral Training

Stanford University, Hugh O McDevitt

Sindbis Virus Vaccine Platform: A Promising Oncolytic Virus-Mediated Approach for Ovarian Cancer Treatment

Pampeno, Christine; Opp, Silvana; Hurtado, Alicia; Meruelo, Daniel

International journal of molecular sciences. 2024 Mar 02; 25(5):

Channeling the Natural Properties of Sindbis Alphavirus for Targeted Tumor Therapy

Pampeno, Christine; Hurtado, Alicia; Opp, Silvana; Meruelo, Daniel

International journal of molecular sciences. 2023 Oct 06; 24(19):

Potent and Targeted Sindbis Virus Platform for Immunotherapy of Ovarian Cancer

Opp, Silvana; Hurtado, Alicia; Pampeno, Christine; Lin, Ziyan; Meruelo, Daniel

Cells. 2022 Dec 24; 12(1):

Combination of a Sindbis-SARS-CoV-2 Spike Vaccine and αOX40 Antibody Elicits Protective Immunity Against SARS-CoV-2 Induced Disease and Potentiates Long-Term SARS-CoV-2-Specific Humoral and T-Cell Immunity

Scaglione, Antonella; Opp, Silvana; Hurtado, Alicia; Lin, Ziyan; Pampeno, Christine; Noval, Maria G; Thannickal, Sara A; Stapleford, Kenneth A; Meruelo, Daniel

Frontiers in immunology. 2021 Oct; 12:719077

Sindbis Virus with Anti-OX40 Overcomes the Immunosuppressive Tumor Microenvironment of Low-Immunogenic Tumors

Scherwitzl, Iris; Opp, Silvana; Hurtado, Alicia M; Pampeno, Christine; Loomis, Cynthia; Kannan, Kasthuri; Yu, Minjun; Meruelo, Daniel

Molecular therapy oncolytics. 2020 Jun 26; 17:431-447

Molecular and metabolic pathways mediating curative treatment of a non-Hodgkin B cell lymphoma by Sindbis viral vectors and anti-4-1BB monoclonal antibody

Yu, Minjun; Scherwitzl, Iris; Opp, Silvana; Tsirigos, Aristotelis; Meruelo, Daniel

Journal for immunotherapy of cancer. 2019 Jul 15; 7(1):185

Systemically Administered Sindbis Virus in Combination with Immune Checkpoint Blockade Induces Curative Anti-tumor Immunity

Scherwitzl, Iris; Hurtado, Alicia; Pierce, Carolyn M; Vogt, Sandra; Pampeno, Christine; Meruelo, Daniel

Molecular therapy oncolytics. 2018 Jun 29; 9:51-63

Looking into laminin receptor: critical discussion regarding the non-integrin 37/67-kDa laminin receptor/RPSA protein

DiGiacomo, Vincent; Meruelo, Daniel

Biological reviews of the Cambridge Philosophical Society. 2016 May; 91(2):288-310

See All Publications (151)