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Daniel P. Depledge

Daniel P. Depledge, PhD

Research Assistant Professor, Department of Medicine

Keywords
Systems Virology, Computational Biology, Transcriptional Regulation, Genomics, Transcriptomics, Molecular Virology
Summary

Research in my lab is focused on several broad themes including: characterizing the roles of diverse base modifications (including m6A) on host and viral RNAs during productive infections; investigating the functions of herpesviral latency-associated transcripts and other non-coding RNAs (including miRNAs) during both lytic and latent infections; and, characterizing the transcriptional complexity of diverse viruses (herpesviruses, adenoviruses, coronaviruses) in distinct cell types, such as epithelial cells and neurons.

This is primarily achieved through the integration of computational biology with a variety of high-throughput molecular techniques to study multiple aspects of virus-host interactions at a genome-wide scale. Specific targets of interest are subsequently followed up using classical molecular biology approaches.

These focus areas and their associated publications are derived from medical subject headings from PubMed.
represents one publication
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*Due to PubMed processing times, the most recent publications may not be reflected in the timeline.

NYU School of Medicine, Microbiology

University College London, Infection & Immunity

Depledge, Daniel P; Srinivas, Kalanghad Puthankalam; Sadaoka, Tomohiko; Bready, Devin; Mori, Yasuko; Placantonakis, Dimitris G; Mohr, Ian; Wilson, Angus C

Nature communications. 2019 Feb 14; 10(1):754

Depledge, Daniel P; Ouwendijk, Werner J D; Sadaoka, Tomohiko; Braspenning, Shirley E; Mori, Yasuko; Cohrs, Randall J; Verjans, Georges M G M; Breuer, Judith

Nature communications. 2018 03 21; 9(1):1167

Rubio, Rosa M; Depledge, Daniel P; Bianco, Christopher; Thompson, Letitia; Mohr, Ian

Genes & development. 2018 12 01; 32(23-24):1472-1484

Depledge, Daniel P; Cudini, Juliana; Kundu, Samit; Atkinson, Claire; Brown, Julianne R; Haque, Tanzina; Houldcroft, Charlotte J; Koay, Evelyn S; McGill, Fiona; Milne, Richard; Whitfield, Tom; Tang, Julian W; Underhill, Gillian; Bergstrom, Tomas; Norberg, Peter; Goldstein, Richard; Solomon, Tom; Breuer, Judith

Journal of infectious diseases. 2018 Oct 05; 218(10):1592-1601

Depledge, Daniel P; Mohr, Ian; Wilson, Angus C

Journal of virology. 2019 01 01; 93(1):

Depledge, Daniel P; Sadaoka, Tomohiko; Ouwendijk, Werner J D

Viruses. 2018 06 28; 10(7):

Depledge, Daniel P; Gray, Eleanor R; Kundu, Samit; Cooray, Samantha; Poulsen, Anja; Aaby, Peter; Breuer, Judith

Journal of virology. 2014 Dec; 88(24):13936-46

Jensen, Nancy J; Depledge, Daniel P; Ng, Terry Fei Fan; Leung, Jessica; Quinlivan, Mark; Radford, Kay W; Folster, Jennifer; Tseng, Hung-Fu; LaRussa, Philip; Jacobsen, Steven J; Breuer, Judith; Schmid, D Scott

Virology. 2020 Jul; 546:38-50