David Fenyo

David Fenyo, PhD

Institute for Systems Genetics

Professor, Department of Biochemistry and Molecular Pharmacology

Keywords
biostatistics, cancer, computational biology, genomics, imaging, pharmacology, proteomics, systems biology
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Summary

Our goal is detailed understanding of the dynamics of cellular processes, and we apply mathematical, statistical and computational methods to solve practical problems in experimental design optimization, quantitative data analysis, and in the modeling of biological systems for generating new hypotheses. The focus of our research is proteomic data analysis: we are developing computational methods and databases for protein identification, characterization and quantitation using mass spectrometry-based proteomics.

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Phone

212-263-2216

Academic office

430 East 29th Street, Alexandria Building East

5th Floor, Room 507

New York, NY 10016

Lab Website
Fenyo Lab
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These focus areas and their associated publications are derived from medical subject headings from PubMed.
represents one publication
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Positions

Professor, Department of Biochemistry and Molecular Pharmacology

Director, Biomedical Informatics Masters Training Program

Director, Systems and Computational Biomedicine PhD Training Program

Graduate Education

PhD from Uppsala University

Human memory B cells targeting Staphylococcus aureus exotoxins are prevalent with skin and soft tissue infection

Pelzek, A J; Shopsin, B; Radke, E E; Tam, K; Ueberheide, B M; Fenyo, D; Brown, S M; Li, Q; Rubin, A; Fulmer, Y; Chiang, W K; Hernandez, D N; El, Bannoudi H; Sause, W E; Sommerfield, A; Thomsen, I P; Miller, A O; Torres, V J; Silverman, G J

MBio. 2018 March-April; 9(2):

Large Scale Identification of Variant Proteins in Glioma Stem Cells

Mostovenko, Ekaterina; Vegvari, Akos; Rezeli, Melinda; Lichti, Cheryl F; Fenyo, David; Wang, Qianghu; Lang, Frederick F; Sulman, Erik P; Sahlin, K Barbara; Marko-Varga, Gyorgy; Nilsson, Carol L

ACS chemical neuroscience. 2018 Jan 17; 9(1):73-79

LINE-1 protein localization and functional dynamics during the cell cycle

Mita, Paolo; Wudzinska, Aleksandra; Sun, Xiaoji; Andrade, Joshua; Nayak, Shruti; Kahler, David J; Badri, Sana; LaCava, John; Ueberheide, Beatrix; Yun, Chi Y; Fenyo, David; Boeke, Jef D

eLife. 2018 Jan 08; 7:

Dissection of affinity captured LINE-1 macromolecular complexes

Taylor, Martin S; Altukhov, Ilya; Molloy, Kelly R; Mita, Paolo; Jiang, Hua; Adney, Emily M; Wudzinska, Aleksandra; Badri, Sana; Ischenko, Dmitry; Eng, George; Burns, Kathleen H; Fenyo, David; Chait, Brian T; Alexeev, Dmitry; Rout, Michael P; Boeke, Jef D; LaCava, John

eLife. 2018 Jan 08; 7:

A Method for Quantifying Molecular Interactions Using Stochastic Modelling and Super-Resolution Microscopy

Bermudez-Hernandez, Keria; Keegan, Sarah; Whelan, Donna R; Reid, Dylan A; Zagelbaum, Jennifer; Yin, Yandong; Ma, Sisi; Rothenberg, Eli; Fenyo, David

Scientific reports. 2017 Nov 01; 7(1):14882-14882

Breast tumors educate the proteome of stromal tissue in an individualized but coordinated manner

Wang, Xuya; Mooradian, Arshag D; Erdmann-Gilmore, Petra; Zhang, Qiang; Viner, Rosa; Davies, Sherri R; Huang, Kuan-Lin; Bomgarden, Ryan; Van Tine, Brian A; Shao, Jieya; Ding, Li; Li, Shunqiang; Ellis, Matthew J; Rogers, John C; Townsend, R Reid; Fenyo, David; Held, Jason M

Science signaling. 2017 Aug 08; 10(491):

GenomeVIP: a cloud platform for genomic variant discovery and interpretation

Mashl, R Jay; Scott, Adam D; Huang, Kuan-Lin; Wyczalkowski, Matthew A; Yoon, Christopher J; Niu, Beifang; DeNardo, Erin; Yellapantula, Venkata D; Handsaker, Robert E; Chen, Ken; Koboldt, Daniel C; Ye, Kai; Fenyo, David; Raphael, Benjamin J; Wendl, Michael C; Ding, Li

Genome research. 2017 Aug; 27(8):1450-1459

Predictive biomarkers of ipilimumab toxicity in metastatic melanoma [Meeting Abstract]

Gowen, M; Tchack, J; Zhou, H; Giles, K M; Paschke, S; Moran, U; Fenyo, D; Tsirigos, A; Pacold, M; Pavlick, A C; Krogsgaard, M; Osman, I

Journal of clinical oncology. 2017 Jun 20; (2017):

See All Publications (163)