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David Fenyo

David Fenyo, PhD

Institute for Systems Genetics

Professor, Department of Biochemistry and Molecular Pharmacology

Keywords
biostatistics, cancer, computational biology, genomics, imaging, pharmacology, proteomics, systems biology
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Summary

Our goal is detailed understanding of the dynamics of cellular processes, and we apply mathematical, statistical and computational methods to solve practical problems in experimental design optimization, quantitative data analysis, and in the modeling of biological systems for generating new hypotheses. The focus of our research is proteomic data analysis: we are developing computational methods and databases for protein identification, characterization and quantitation using mass spectrometry-based proteomics.

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Phone

212-263-2216

Academic office

430 East 29th Street, Alexandria Building East

5th Floor, Room 507

New York, NY 10016

Lab Website
Fenyo Lab
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These focus areas and their associated publications are derived from medical subject headings from PubMed.
represents one publication
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Positions

Professor, Department of Biochemistry and Molecular Pharmacology

Co-Director, Bioinformatics Collaborative Core

Director, Biomedical Informatics Masters Training Program

Director, Systems and Computational Biomedicine PhD Training Program

Graduate Education

PhD from Uppsala University

Breast tumors educate the proteome of stromal tissue in an individualized but coordinated manner

Wang, Xuya; Mooradian, Arshag D; Erdmann-Gilmore, Petra; Zhang, Qiang; Viner, Rosa; Davies, Sherri R; Huang, Kuan-Lin; Bomgarden, Ryan; Van Tine, Brian A; Shao, Jieya; Ding, Li; Li, Shunqiang; Ellis, Matthew J; Rogers, John C; Townsend, R Reid; Fenyo, David; Held, Jason M

Science signaling. 2017 Aug 8; 10(491):?-?

GenomeVIP: a cloud platform for genomic variant discovery and interpretation

Mashl, R Jay; Scott, Adam D; Huang, Kuan-Lin; Wyczalkowski, Matthew A; Yoon, Christopher J; Niu, Beifang; DeNardo, Erin; Yellapantula, Venkata D; Handsaker, Robert E; Chen, Ken; Koboldt, Daniel C; Ye, Kai; Fenyo, David; Raphael, Benjamin J; Wendl, Michael C; Ding, Li

Genome research. 2017 Aug; 27(8):1450-1459

Predictive biomarkers of ipilimumab toxicity in metastatic melanoma [Meeting Abstract]

Gowen, M; Tchack, J; Zhou, H; Giles, K M; Paschke, S; Moran, U; Fenyo, D; Tsirigos, A; Pacold, M; Pavlick, A C; Krogsgaard, M; Osman, I

Journal of clinical oncology. 2017 Jun 20; Conference:(2017):

A Systems Biology Approach Identifies FUT8 as a Driver of Melanoma Metastasis

Agrawal, Praveen; Fontanals-Cirera, Barbara; Sokolova, Elena; Jacob, Samson; Vaiana, Christopher A; Argibay, Diana; Davalos, Veronica; McDermott, Meagan; Nayak, Shruti; Darvishian, Farbod; Castillo, Mireia; Ueberheide, Beatrix; Osman, Iman; Fenyo, David; Mahal, Lara K; Hernando, Eva

Cancer cell. 2017 Jun 12; 31(6):804-819.e7

Endothelium-Independent Primitive Myxoid Vascularization Creates Invertebrate-Like Channels to Maintain Blood Supply in Optic Gliomas

Snuderl, Matija; Zhang, Guoan; Wu, Pamela; Jennings, Tara S; Shroff, Seema; Ortenzi, Valerio; Jain, Rajan; Cohen, Benjamin; Reidy, Jason J; Dushay, Mitchell S; Wisoff, Jeffrey H; Harter, David H; Karajannis, Matthias A; Fenyo, David; Neubert, Thomas A; Zagzag, David

American journal of pathology. 2017 Jun 9; 187(8):1867-1878

BIOCHEMICAL COMPOSITION AND BIOLOGICAL FUNCTION OF MYXOID MATRIX IN OPTIC GLIOMAS [Meeting Abstract]

Snuderl, Matija; Zhang, Guoan; Wu, Pamela; Jennings, Tara; Shroff, Seema; Ortenzi, Valerio; Jain, Rajan; Cohen, Benjamin; Reidy, Jason; Dushay, Mitchell; Wisoff, Jeffrey; Harter, David; Karajannis, Matthias; Fenyo, David; Neubert, Thomas; Zagzag, David

Neuro-oncology. 2017 JUN; 19:33-33

Methods, tools and current perspectives in proteogenomics

Ruggles, Kelly V; Krug, Karsten; Wang, Xiaojing; Clauser, Karl R; Wang, Jing; Payne, Samuel H; Fenyo, David; Zhang, Bing; Mani, D R

Molecular & cellular proteomics. 2017 Apr 29; 16(6):959-981

Corrigendum: Proteogenomic integration reveals therapeutic targets in breast cancer xenografts

Huang, Kuan-Lin; Li, Shunqiang; Mertins, Philipp; Cao, Song; Gunawardena, Harsha P; Ruggles, Kelly V; Mani, D R; Clauser, Karl R; Tanioka, Maki; Usary, Jerry; Kavuri, Shyam M; Xie, Ling; Yoon, Christopher; Qiao, Jana W; Wrobel, John; Wyczalkowski, Matthew A; Erdmann-Gilmore, Petra; Snider, Jacqueline E; Hoog, Jeremy; Singh, Purba; Niu, Beifang; Guo, Zhanfang; Sun, Sam Qiancheng; Sanati, Souzan; Kawaler, Emily; Wang, Xuya; Scott, Adam; Ye, Kai; McLellan, Michael D; Wendl, Michael C; Malovannaya, Anna; Held, Jason M; Gillette, Michael A; Fenyo, David; Kinsinger, Christopher R; Mesri, Mehdi; Rodriguez, Henry; Davies, Sherri R; Perou, Charles M; Ma, Cynthia; Townsend, R Reid; Chen, Xian; Carr, Steven A; Ellis, Matthew J; Ding, Li

Nature communications. 2017 Apr 25; 8:15479-15479

See All Publications (155)