David Fenyo

David Fenyo, PhD

Institute for Systems Genetics

Professor, Department of Biochemistry and Molecular Pharmacology

Keywords
biostatistics, cancer, computational biology, genomics, imaging, pharmacology, proteomics, systems biology
Summary

Our goal is detailed understanding of the dynamics of cellular processes, and we apply mathematical, statistical and computational methods to solve practical problems in experimental design optimization, quantitative data analysis, and in the modeling of biological systems for generating new hypotheses. The focus of our research is proteomic data analysis: we are developing computational methods and databases for protein identification, characterization and quantitation using mass spectrometry-based proteomics.

Phone

917-754-6066

Academic office

435 E 30th St

9th Floor, Room 907

New York, NY 10016

Lab Website
Fenyo Lab
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Positions

Professor, Department of Biochemistry and Molecular Pharmacology at NYU Grossman School of Medicine

Director, Biomedical Informatics Masters Training Program

Director, Systems and Computational Biomedicine PhD Training Program

Graduate Education

PhD from Uppsala University

Postdoctoral Training

Rockefeller University, Chait Lab

Melanoma Proteomics Unveiled: Harmonizing Diverse Data Sets for Biomarker Discovery and Clinical Insights via MEL-PLOT

Bartha, Áron; Weltz, Boglárka; Betancourt, Lazaro Hiram; Gil, Jeovanis; Pinto de Almeida, Natália; Bianchini, Giampaolo; Szeitz, Beáta; Szadai, Leticia; Pla, Indira; Kemény, Lajos V; Jánosi, Ágnes Judit; Hong, Runyu; Rajeh, Ahmad; Nogueira, Fábio; Doma, Viktória; Woldmar, Nicole; Guedes, Jéssica; Újfaludi, Zsuzsanna; Kim, Yonghyo; Szarvas, Tibor; Pahi, Zoltan; Pankotai, Tibor; Szasz, A Marcell; Sanchez, Aniel; Baldetorp, Bo; Tímár, József; Németh, István Balázs; Kárpáti, Sarolta; Appelqvist, Roger; Domont, Gilberto Barbosa; Pawlowski, Krzysztof; Wieslander, Elisabet; Malm, Johan; Fenyo, David; Horvatovich, Peter; Marko-Varga, György; Győrffy, Balázs

Journal of proteome research. 2025 May 05;

An integrated approach for the accurate detection of HERV-K HML-2 transcription and protein synthesis

Gleason, Charles; Terry, Sandra N; Hernandez, Matthew M; Jacob, Samson; Fenyo, David; Johnson, Jeffrey R; Deikus, Gintaras; Francoeur, Nancy; Hahn, Aana; Sebra, Robert; Zamarin, Dmitriy; Molina, Henrik; Simon, Viviana; Mulder, Lubbertus C F

Nucleic acids research. 2025 Jan 11; 53(2):

B cell-extrinsic and intrinsic factors linked to early immune repletion after anti-CD20 therapy in patients with multiple sclerosis of African ancestry

Silverman, Gregg J; Amarnani, Abhimanyu N; Armini, Arnaldo A; Kim, Angie; Kopinsky, Hannah; Fenyo, David; Kister, Ilya

Frontiers in immunology. 2025 Jun; 16:1590165

Modulation of GPR133 (ADGRD1) signaling by its intracellular interaction partner extended synaptotagmin 1

Stephan, Gabriele; Haddock, Sara; Wang, Shuai; Erdjument-Bromage, Hediye; Liu, Wenke; Ravn-Boess, Niklas; Frenster, Joshua D; Bready, Devin; Cai, Julia; Ronnen, Rebecca; Sabio-Ortiz, Jonathan; Fenyo, David; Neubert, Thomas A; Placantonakis, Dimitris G

Cell reports. 2024 May 28; 43(5):114229

Digitalomics - digital transformation leading to omics insights

Balasubramaniam, Nandha Kumar; Penberthy, Scott; Fenyo, David; Viessmann, Nina; Russmann, Christoph; Borchers, Christoph H

Expert review of proteomics. 2024 Nov; 21(9-10):337-344

Longitudinal gut microbiome analyses and blooms of pathogenic strains during lupus disease flares

Azzouz, Doua F; Chen, Ze; Izmirly, Peter M; Chen, Lea Ann; Li, Zhi; Zhang, Chongda; Mieles, David; Trujillo, Kate; Heguy, Adriana; Pironti, Alejandro; Putzel, Greg G; Schwudke, Dominik; Fenyo, David; Buyon, Jill P; Alekseyenko, Alexander V; Gisch, Nicolas; Silverman, Gregg J

Annals of the rheumatic diseases. 2023 Oct; 82(10):1315-1327

Proteogenomic analysis of chemo-refractory high-grade serous ovarian cancer

Chowdhury, Shrabanti; Kennedy, Jacob J; Ivey, Richard G; Murillo, Oscar D; Hosseini, Noshad; Song, Xiaoyu; Petralia, Francesca; Calinawan, Anna; Savage, Sara R; Berry, Anna B; Reva, Boris; Ozbek, Umut; Krek, Azra; Ma, Weiping; da Veiga Leprevost, Felipe; Ji, Jiayi; Yoo, Seungyeul; Lin, Chenwei; Voytovich, Uliana J; Huang, Yajue; Lee, Sun-Hee; Bergan, Lindsay; Lorentzen, Travis D; Mesri, Mehdi; Rodriguez, Henry; Hoofnagle, Andrew N; Herbert, Zachary T; Nesvizhskii, Alexey I; Zhang, Bing; Whiteaker, Jeffrey R; Fenyo, David; McKerrow, Wilson; Wang, Joshua; Schürer, Stephan C; Stathias, Vasileios; Chen, X Steven; Barcellos-Hoff, Mary Helen; Starr, Timothy K; Winterhoff, Boris J; Nelson, Andrew C; Mok, Samuel C; Kaufmann, Scott H; Drescher, Charles; Cieslik, Marcin; Wang, Pei; Birrer, Michael J; Paulovich, Amanda G

Cell. 2023 Aug 03; 186(16):3476-3498.e35

Transposon insertion profiling by sequencing (TIPseq) identifies novel LINE-1 insertions in human sperm

Berteli, Thalita S; Wang, Fang; McKerrow, Wilson; Navarro, Paula A; Fenyo, David; Boeke, Jef D; Kohlrausch, Fabiana B; Keefe, David L

Journal of assisted reproduction & genetics. 2023 Aug; 40(8):1835-1843

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