David Fenyo

My Research

Keywords

biostatistics, cancer, computational biology, genomics, imaging, pharmacology, proteomics, systems biology

Summary

Our goal is detailed understanding of the dynamics of cellular processes, and we apply mathematical, statistical and computational methods to solve practical problems in experimental design optimization, quantitative data analysis, and in the modeling of biological systems for generating new hypotheses. The focus of our research is proteomic data analysis: we are developing computational methods and databases for protein identification, characterization and quantitation using mass spectrometry-based proteomics.

Contact

Phone

212-263-2216

david.fenyo@nyumc.org

Academic office

430 East 29th Street, Alexandria Building East

5th Floor, Room 507

New York, NY 10016

Lab Website

Fenyo Lab

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Research Focus Timeline

These focus areas and their associated publications are derived from medical subject headings from PubMed.

represents one publication

Positions & Education

Positions

Professor, Department of Biochemistry and Molecular Pharmacology

Co-Director, Bioinformatics Collaborative Core

Director, Biomedical Informatics Masters Training Program

Director, Systems and Computational Biomedicine PhD Training Program

Education and training

PhD from Uppsala University

PhD from Western Governors University

Selected Publications

A Systems Biology Approach Identifies FUT8 as a Driver of Melanoma Metastasis

Agrawal, Praveen; Fontanals-Cirera, Barbara; Sokolova, Elena; Jacob, Samson; Vaiana, Christopher A; Argibay, Diana; Davalos, Veronica; McDermott, Meagan; Nayak, Shruti; Darvishian, Farbod; Castillo, Mireia; Ueberheide, Beatrix; Osman, Iman; Fenyo, David; Mahal, Lara K; Hernando, Eva

Cancer cell. 2017 Jun 12; 31(6):804-819.e7

Endothelium-Independent Primitive Myxoid Vascularization Creates Invertebrate-Like Channels to Maintain Blood Supply in Optic Gliomas

Snuderl, Matija; Zhang, Guoan; Wu, Pamela; Jennings, Tara S; Shroff, Seema; Ortenzi, Valerio; Jain, Rajan; Cohen, Benjamin; Reidy, Jason J; Dushay, Mitchell S; Wisoff, Jeffrey H; Harter, David H; Karajannis, Matthias A; Fenyo, David; Neubert, Thomas A; Zagzag, David

American journal of pathology. 2017 Jun 9; ?-?

BIOCHEMICAL COMPOSITION AND BIOLOGICAL FUNCTION OF MYXOID MATRIX IN OPTIC GLIOMAS [Meeting Abstract]

Snuderl, Matija; Zhang, Guoan; Wu, Pamela; Jennings, Tara; Shroff, Seema; Ortenzi, Valerio; Jain, Rajan; Cohen, Benjamin; Reidy, Jason; Dushay, Mitchell; Wisoff, Jeffrey; Harter, David; Karajannis, Matthias; Fenyo, David; Neubert, Thomas; Zagzag, David

Neuro-oncology. 2017 JUN; 19:33-33

Methods, tools and current perspectives in proteogenomics

Ruggles, Kelly V; Krug, Karsten; Wang, Xiaojing; Clauser, Karl R; Wang, Jing; Payne, Samuel H; Fenyo, David; Zhang, Bing; Mani, D R

Molecular & cellular proteomics. 2017 Apr 29; 16(6):959-981

Corrigendum: Proteogenomic integration reveals therapeutic targets in breast cancer xenografts

Huang, Kuan-Lin; Li, Shunqiang; Mertins, Philipp; Cao, Song; Gunawardena, Harsha P; Ruggles, Kelly V; Mani, D R; Clauser, Karl R; Tanioka, Maki; Usary, Jerry; Kavuri, Shyam M; Xie, Ling; Yoon, Christopher; Qiao, Jana W; Wrobel, John; Wyczalkowski, Matthew A; Erdmann-Gilmore, Petra; Snider, Jacqueline E; Hoog, Jeremy; Singh, Purba; Niu, Beifang; Guo, Zhanfang; Sun, Sam Qiancheng; Sanati, Souzan; Kawaler, Emily; Wang, Xuya; Scott, Adam; Ye, Kai; McLellan, Michael D; Wendl, Michael C; Malovannaya, Anna; Held, Jason M; Gillette, Michael A; Fenyo, David; Kinsinger, Christopher R; Mesri, Mehdi; Rodriguez, Henry; Davies, Sherri R; Perou, Charles M; Ma, Cynthia; Townsend, R Reid; Chen, Xian; Carr, Steven A; Ellis, Matthew J; Ding, Li

Nature communications. 2017 Apr 25; 8:15479-15479

Proteogenomic integration reveals therapeutic targets in breast cancer xenografts

Huang, Kuan-Lin; Li, Shunqiang; Mertins, Philipp; Cao, Song; Gunawardena, Harsha P; Ruggles, Kelly V; Mani, D R; Clauser, Karl R; Tanioka, Maki; Usary, Jerry; Kavuri, Shyam M; Xie, Ling; Yoon, Christopher; Qiao, Jana W; Wrobel, John; Wyczalkowski, Matthew A; Erdmann-Gilmore, Petra; Snider, Jacqueline E; Hoog, Jeremy; Singh, Purba; Niu, Beifung; Guo, Zhanfang; Sun, Sam Qiancheng; Sanati, Souzan; Kawaler, Emily; Wang, Xuya; Scott, Adam; Ye, Kai; McLellan, Michael D; Wendl, Michael C; Malovannaya, Anna; Held, Jason M; Gillette, Michael A; Fenyo, David; Kinsinger, Christopher R; Mesri, Mehdi; Rodriguez, Henry; Davies, Sherri R; Perou, Charles M; Ma, Cynthia; Reid Townsend, R; Chen, Xian; Carr, Steven A; Ellis, Matthew J; Ding, Li

Nature communications. 2017 Mar 28; 8:14864-14864

Synthesis, debugging, and effects of synthetic chromosome consolidation: synVI and beyond

Mitchell, Leslie A; Wang, Ann; Stracquadanio, Giovanni; Kuang, Zheng; Wang, Xuya; Yang, Kun; Richardson, Sarah; Martin, J Andrew; Zhao, Yu; Walker, Roy; Luo, Yisha; Dai, Hongjiu; Dong, Kang; Tang, Zuojian; Yang, Yanling; Cai, Yizhi; Heguy, Adriana; Ueberheide, Beatrix; Fenyo, David; Dai, Junbiao; Bader, Joel S; Boeke, Jef D

Science. 2017 Mar 10; 355(6329):?-?

Low escape-rate genome safeguards with minimal molecular perturbation of Saccharomyces cerevisiae

Agmon, Neta; Tang, Zuojian; Yang, Kun; Sutter, Ben; Ikushima, Shigehito; Cai, Yizhi; Caravelli, Katrina; Martin, James A; Sun, Xiaoji; Choi, Woo Jin; Zhang, Allen; Stracquadanio, Giovanni; Hao, Haiping; Tu, Benjamin P; Fenyo, David; Bader, Joel S; Boeke, Jef D

Proceedings of the National Academy of Sciences of the United States of America (PNAS). 2017 Feb 7; 114(8):E1470-E1479

See All Publications (152)