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David Fenyo

David Fenyo, PhD

Institute for Systems Genetics

Professor, Department of Biochemistry and Molecular Pharmacology

Keywords
biostatistics, cancer, computational biology, genomics, imaging, pharmacology, proteomics, systems biology
Summary

Our goal is detailed understanding of the dynamics of cellular processes, and we apply mathematical, statistical and computational methods to solve practical problems in experimental design optimization, quantitative data analysis, and in the modeling of biological systems for generating new hypotheses. The focus of our research is proteomic data analysis: we are developing computational methods and databases for protein identification, characterization and quantitation using mass spectrometry-based proteomics.

Phone

917-754-6066

Academic office

435 E 30th St

9th Floor, Room 907

New York, NY 10016

Lab Website
Fenyo Lab
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Positions

Professor, Department of Biochemistry and Molecular Pharmacology at NYU Grossman School of Medicine

Director, Biomedical Informatics Masters Training Program

Director, Systems and Computational Biomedicine PhD Training Program

Graduate Education

PhD from Uppsala University

Postdoctoral Training

Rockefeller University, Chait Lab

Highly synergistic combinations of nanobodies that target SARS-CoV-2 and are resistant to escape

Mast, Fred D; Fridy, Peter C; Ketaren, Natalia E; Wang, Junjie; Jacobs, Erica Y; Olivier, Jean Paul; Sanyal, Tanmoy; Molloy, Kelly R; Schmidt, Fabian; Rutkowska, Magdalena; Weisblum, Yiska; Rich, Lucille M; Vanderwall, Elizabeth R; Dambrauskas, Nicholas; Vigdorovich, Vladimir; Keegan, Sarah; Jiler, Jacob B; Stein, Milana E; Olinares, Paul Dominic B; Herlands, Louis; Hatziioannou, Theodora; Sather, D Noah; Debley, Jason S; Fenyö, David; Sali, Andrej; Bieniasz, Paul D; Aitchison, John D; Chait, Brian T; Rout, Michael P

eLife. 2021 12 07; 10:

Deep learning and pathomics analyses reveal cell nuclei as important features for mutation prediction of BRAF-mutated melanomas

Kim, Randie H; Nomikou, Sofia; Coudray, Nicolas; Jour, George; Dawood, Zarmeena; Hong, Runyu; Esteva, Eduardo; Sakellaropoulos, Theodore; Donnelly, Douglas; Moran, Una; Hatzimemos, Aristides; Weber, Jeffrey S; Razavian, Narges; Aifantis, Iannis; Fenyo, David; Snuderl, Matija; Shapiro, Richard; Berman, Russell S; Osman, Iman; Tsirigos, Aristotelis

Journal of investigative dermatology. 2021 Oct 30;

Predicting endometrial cancer subtypes and molecular features from histopathology images using multi-resolution deep learning models

Hong, Runyu; Liu, Wenke; DeLair, Deborah; Razavian, Narges; Fenyö, David

Cell reports. Medicine. 2021 Sep 21; 2(9):100400

Proteogenomic characterization of pancreatic ductal adenocarcinoma

Cao, Liwei; Huang, Chen; Cui Zhou, Daniel; Hu, Yingwei; Lih, T Mamie; Savage, Sara R; Krug, Karsten; Clark, David J; Schnaubelt, Michael; Chen, Lijun; da Veiga Leprevost, Felipe; Eguez, Rodrigo Vargas; Yang, Weiming; Pan, Jianbo; Wen, Bo; Dou, Yongchao; Jiang, Wen; Liao, Yuxing; Shi, Zhiao; Terekhanova, Nadezhda V; Cao, Song; Lu, Rita Jui-Hsien; Li, Yize; Liu, Ruiyang; Zhu, Houxiang; Ronning, Peter; Wu, Yige; Wyczalkowski, Matthew A; Easwaran, Hariharan; Danilova, Ludmila; Mer, Arvind Singh; Yoo, Seungyeul; Wang, Joshua M; Liu, Wenke; Haibe-Kains, Benjamin; Thiagarajan, Mathangi; Jewell, Scott D; Hostetter, Galen; Newton, Chelsea J; Li, Qing Kay; Roehrl, Michael H; Fenyö, David; Wang, Pei; Nesvizhskii, Alexey I; Mani, D R; Omenn, Gilbert S; Boja, Emily S; Mesri, Mehdi; Robles, Ana I; Rodriguez, Henry; Bathe, Oliver F; Chan, Daniel W; Hruban, Ralph H; Ding, Li; Zhang, Bing; Zhang, Hui

Cell. 2021 Sep 16; 184(19):5031-5052.e26

Adenosine A2A receptor null chondrocyte transcriptome resembles that of human osteoarthritic chondrocytes

Castro, Cristina M; Corciulo, Carmen; Friedman, Benjamin; Li, Zhi; Jacob, Samson; Fenyo, David; Cronstein, Bruce N

Purinergic signalling. 2021 Sep; 17(3):439-448

A proteogenomic portrait of lung squamous cell carcinoma

Satpathy, Shankha; Krug, Karsten; Jean Beltran, Pierre M; Savage, Sara R; Petralia, Francesca; Kumar-Sinha, Chandan; Dou, Yongchao; Reva, Boris; Kane, M Harry; Avanessian, Shayan C; Vasaikar, Suhas V; Krek, Azra; Lei, Jonathan T; Jaehnig, Eric J; Omelchenko, Tatiana; Geffen, Yifat; Bergstrom, Erik J; Stathias, Vasileios; Christianson, Karen E; Heiman, David I; Cieslik, Marcin P; Cao, Song; Song, Xiaoyu; Ji, Jiayi; Liu, Wenke; Li, Kai; Wen, Bo; Li, Yize; Gümüş, Zeynep H; Selvan, Myvizhi Esai; Soundararajan, Rama; Visal, Tanvi H; Raso, Maria G; Parra, Edwin Roger; Babur, Özgün; Vats, Pankaj; Anand, Shankara; Schraink, Tobias; Cornwell, MacIntosh; Rodrigues, Fernanda Martins; Zhu, Houxiang; Mo, Chia-Kuei; Zhang, Yuping; da Veiga Leprevost, Felipe; Huang, Chen; Chinnaiyan, Arul M; Wyczalkowski, Matthew A; Omenn, Gilbert S; Newton, Chelsea J; Schurer, Stephan; Ruggles, Kelly V; Fenyö, David; Jewell, Scott D; Thiagarajan, Mathangi; Mesri, Mehdi; Rodriguez, Henry; Mani, Sendurai A; Udeshi, Namrata D; Getz, Gad; Suh, James; Li, Qing Kay; Hostetter, Galen; Paik, Paul K; Dhanasekaran, Saravana M; Govindan, Ramaswamy; Ding, Li; Robles, Ana I; Clauser, Karl R; Nesvizhskii, Alexey I; Wang, Pei; Carr, Steven A; Zhang, Bing; Mani, D R; Gillette, Michael A

Cell. 2021 Aug 05; 184(16):4348-4371.e40

The role of retrotransposable elements in ageing and age-associated diseases

Gorbunova, Vera; Seluanov, Andrei; Mita, Paolo; McKerrow, Wilson; Fenyö, David; Boeke, Jef D; Linker, Sara B; Gage, Fred H; Kreiling, Jill A; Petrashen, Anna P; Woodham, Trenton A; Taylor, Jackson R; Helfand, Stephen L; Sedivy, John M

Nature. 2021 08; 596(7870):43-53

Predictive modeling of morbidity and mortality in COVID-19 hospitalized patients and its clinical implications

Wang, Joshua M; Liu, Wenke; Chen, Xiaoshan; McRae, Michael P; McDevitt, John T; Fenyo, David

Journal of medical Internet research. 2021 Jul 09; 23(7):e29514

See All Publications (238)

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