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David Fenyo

David Fenyo, PhD

Institute for Systems Genetics

Professor, Department of Biochemistry and Molecular Pharmacology

Keywords
biostatistics, cancer, computational biology, genomics, imaging, pharmacology, proteomics, systems biology
Summary

Our goal is detailed understanding of the dynamics of cellular processes, and we apply mathematical, statistical and computational methods to solve practical problems in experimental design optimization, quantitative data analysis, and in the modeling of biological systems for generating new hypotheses. The focus of our research is proteomic data analysis: we are developing computational methods and databases for protein identification, characterization and quantitation using mass spectrometry-based proteomics.

Phone

917-754-6066

Academic office

435 E 30th St

9th Floor, Room 907

New York, NY 10016

Lab Website
Fenyo Lab
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These focus areas and their associated publications are derived from medical subject headings from PubMed.
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Positions

Professor, Department of Biochemistry and Molecular Pharmacology

Director, Biomedical Informatics Masters Training Program

Director, Systems and Computational Biomedicine PhD Training Program

Graduate Education

PhD from Uppsala University

Postdoctoral Training

Rockefeller University, Chait Lab

Macrophage-derived netrin-1 promotes abdominal aortic aneurysm formation by activating MMP3 in vascular smooth muscle cells

Hadi, Tarik; Boytard, Ludovic; Silvestro, Michele; Alebrahim, Dornazsadat; Jacob, Samson; Feinstein, Jordyn; Barone, Krista; Spiro, Wes; Hutchison, Susan; Simon, Russell; Rateri, Debra; Pinet, Florence; Fenyo, David; Adelman, Mark; Moore, Kathryn J; Eltzschig, Holger K; Daugherty, Alan; Ramkhelawon, Bhama

Nature communications. 2018 11 27; 9(1):5022

Classification and Mutation Prediction from Non-Small Cell Lung Cancer Histopathology Images Using Deep Learning [Meeting Abstract]

Ocampo, P.; Moreira, A.; Coudray, N.; Sakellaropoulos, T.; Narula, N.; Snuderl, M.; Fenyo, D.; Razavian, N.; Tsirigos, A.

Journal of thoracic oncology. 2018 OCT; 13:S562-S562

Spatiotemporal dynamics of homologous recombination repair at single collapsed replication forks

Whelan, Donna R; Lee, Wei Ting C; Yin, Yandong; Ofri, Dylan M; Bermudez-Hernandez, Keria; Keegan, Sarah; Fenyo, David; Rothenberg, Eli

Nature communications. 2018 09 24; 9(1):3882

A2A Adenosine Receptor Stimulation Switches TGF-beta Signaling to Promote Chondrocyte Proliferation and Cartilage Regeneration [Meeting Abstract]

Corciulo, Carmen; Castro, Cristina; Jacob, Samson; Fenyo, David; Kennedy, Oran; Cronstein, Bruce N.

Arthritis & rheumatology. 2018 SEP; 70:?-?

Integrative omics analyses broaden treatment targets in human cancer

Sengupta, S; Sun, S Q; Huang, K -L; Oh, C; Bailey, M H; Varghese, R; Wyczalkowski, M A; Ning, J; Tripathi, P; McMichael, J F; Johnson, K J; Kandoth, C; Welch, J; Ma, C; Wendl, M C; Payne, S H; Fenyo, D; Townsend, R R; Dipersio, J F; Chen, F; Ding, L

Genome medicine. 2018 Jul 27; 10(1):

Transcription factor profiling reveals molecular choreography and key regulators of human retrotransposon expression

Sun, Xiaoji; Wang, Xuya; Tang, Zuojian; Grivainis, Mark; Kahler, David; Yun, Chi; Mita, Paolo; Fenyo, David; Boeke, Jef D

Proceedings of the National Academy of Sciences of the United States of America (PNAS). 2018 06 12; 115(24):E5526-E5535

Mass spectrometry-based proteomics reveals potential roles of NEK9 and MAP2K4 in resistance to PI3K inhibitors in triple negative breast cancers

Mundt, Filip; Rajput, Sandeep; Li, Shunqiang; Ruggles, Kelly V; Mooradian, Arshag D; Mertins, Philipp; Gillette, Michael A; Krug, Karsten; Guo, Zhanfang; Hoog, Jeremy; Erdmann-Gilmore, Petra; Primeau, Tina; Huang, Shixia; Edwards, Dean P; Wang, Xiaowei; Wang, Xuya; Kawaler, Emily; Mani, D R; Clauser, Karl R; Gao, Feng; Luo, Jingqin; Davies, Sherri R; Johnson, Gary L; Huang, Kuan-Lin; Yoon, Christopher J; Ding, Li; Fenyo, David; Ellis, Matthew J; Townsend, R Reid; Held, Jason M; Carr, Steven A; Ma, Cynthia X

Cancer research. 2018 May 15; 78(10):2732-2746

A toolbox of immunoprecipitation-grade monoclonal antibodies to human transcription factors

Venkataraman, Anand; Yang, Kun; Irizarry, Jose; Mackiewicz, Mark; Mita, Paolo; Kuang, Zheng; Xue, Lin; Ghosh, Devlina; Liu, Shuang; Ramos, Pedro; Hu, Shaohui; Bayron Kain, Diane; Keegan, Sarah; Saul, Richard; Colantonio, Simona; Zhang, Hongyan; Behn, Florencia Pauli; Song, Guang; Albino, Edisa; Asencio, Lillyann; Ramos, Leonardo; Lugo, Luvir; Morell, Gloriner; Rivera, Javier; Ruiz, Kimberly; Almodovar, Ruth; Nazario, Luis; Murphy, Keven; Vargas, Ivan; Rivera-Pacheco, Zully Ann; Rosa, Christian; Vargas, Moises; McDade, Jessica; Clark, Brian S; Yoo, Sooyeon; Khambadkone, Seva G; de Melo, Jimmy; Stevanovic, Milanka; Jiang, Lizhi; Li, Yana; Yap, Wendy Y; Jones, Brittany; Tandon, Atul; Campbell, Elliot; Montelione, Gaetano T; Anderson, Stephen; Myers, Richard M; Boeke, Jef D; Fenyo, David; Whiteley, Gordon; Bader, Joel S; Pino, Ignacio; Eichinger, Daniel J; Zhu, Heng; Blackshaw, Seth

Nature methods. 2018 May; 15(5):330-338

See All Publications (175)