Professor, Department of Child and Adolescent Psychiatry
Professor, Department of Neuroscience and Physiology
My lab and I are interested in how the mammalian brain processes and remembers information. Using a rat model system, we focus on the discrimination and memory of odors. In addition, we employ electrophysiological, behavioral, neuroanatomical, and pharmacological approaches to explore the neurobiology of memory and the role of experience in sensory system function.
The underlying hypothesis of much of our work is that memory plays a crucial role in basic sensory discrimination. We are also interested in how experience and pathology across the life span can influence sensory system function and perception.
For example, we are interested in how disruptions of even very simple neural mechanisms during early development can lead to a cascade of long-lasting consequences for brain and behavior, and how the deposition of amyloid proteins in the brain in an animal model of Alzheimer’s disease shape sensory coding and perception.
A TEDx Talk, “The Power of the Sense of Smell,” summarizes aspects of our work.
PhD from McMaster University
Brain research. 2020 Sep 17; 1748:147128
Nature communications. 2020 Feb 28; 11(1):1119
Nature communications. 2020 Jan 31; 11(1):648
Behavior genetics. 2020 Jan; 50(1):3-13
Frontiers in behavioral neuroscience. 2020 Mar; 14:35
Brain research. 2019 Dec 19; 1729:146617
Scientific reports. 2019 Nov 13; 9(1):16701
Proceedings of the National Academy of Sciences of the United States of America (PNAS). 2019 Nov 05; 116(45):22821-22832