Skip to Main Content
Drew R. Jones

Drew R. Jones, PhD

Assistant Professor, Department of Biochemistry and Molecular Pharmacology

Assistant Professor, Department of Radiation Oncology

Summary

Dr. Jones’ laboratory is focused on the development and application of metabolomics technology for global untargeted analyses with mass spectrometry. Reliable identification of metabolites in untargeted experiments is a major bottle neck for the field. To address this challenge, Dr. Jones has developed a method called Metabolome Identification by Systematic Stable Isotope Labeling Experiments (MISSILE) which can determine the chemical formula of any metabolite de novo, greatly improving the confidence of such annotations. Biologically, this method is being applied to the study of stress response in yeast and in disease states such as Alzheimer’s.

Is this your profile?
Edit profile

Positions

Assistant Professor, Department of Biochemistry and Molecular Pharmacology at NYU Grossman School of Medicine

Assistant Professor, Department of Radiation Oncology at NYU Grossman School of Medicine

Director, Metabolomics Core Resource Laboratory

Graduate Education

PhD from University of Arkansas for Medical Sciences

Limited Environmental Serine and Glycine Confer Brain Metastasis Sensitivity to PHGDH Inhibition

Ngo, Bryan; Kim, Eugenie; Osorio-Vasquez, Victoria; Doll, Sophia; Bustraan, Sophia; Liang, Roger J; Luengo, Alba; Davidson, Shawn M; Ali, Ahmed; Ferraro, Gino B; Fischer, Grant M; Eskandari, Roozbeh; Kang, Diane S; Ni, Jing; Plasger, Ariana; Rajasekhar, Vinagolu K; Kastenhuber, Edward R; Bacha, Sarah; Sriram, Roshan K; Stein, Benjamin D; Bakhoum, Samuel F; Snuderl, Matija; Cotzia, Paolo; Healey, John H; Mainolfi, Nello; Suri, Vipin; Friedman, Adam; Manfredi, Mark; Sabatini, David M; Jones, Drew R; Yu, Min; Zhao, Jean J; Jain, Rakesh K; Keshari, Kayvan R; Davies, Michael A; Vander Heiden, Matthew G; Hernando, Eva; Mann, Matthias; Cantley, Lewis C; Pacold, Michael E

Cancer discovery. 2020 Jun 22;

JUMPm: A Tool for Large-Scale Identification of Metabolites in Untargeted Metabolomics

Wang, Xusheng; Cho, Ji-Hoon; Poudel, Suresh; Li, Yuxin; Jones, Drew R; Shaw, Timothy I; Tan, Haiyan; Xie, Boer; Peng, Junmin

Metabolites. 2020 May 12; 10(5):

Selective alanine transporter utilization creates a targetable metabolic niche in pancreatic cancer

Parker, Seth J; Amendola, Caroline R; Hollinshead, Kate E R; Yu, Qijia; Yamamoto, Keisuke; Encarnacion-Rosado, Joel; Rose, Rebecca E; LaRue, Madeleine M; Sohn, Albert S W; Biancur, Doug E; Paulo, Joao A; Gygi, Steven P; Jones, Drew R; Wang, Huamin; Philips, Mark R; Bar-Sagi, Dafna; Mancias, Joseph D; Kimmelman, Alec C

Cancer discovery. 2020 Apr 27;

IL-17 Inhibition in Spondyloarthritis Associates with Subclinical Gut Microbiome Perturbations and a Distinctive IL-25-Driven Intestinal Inflammation

Manasson, Julia; Wallach, David S; Guggino, Giuliana; Stapylton, Matthew; Badri, Michelle H; Solomon, Gary; Reddy, Soumya M; Coras, Roxana; Aksenov, Alexander A; Jones, Drew R; Girija, Parvathy V; Neimann, Andrea L; Heguy, Adriana; Segal, Leopoldo N; Dorrestein, Pieter C; Bonneau, Richard; Guma, Monica; Ciccia, Francesco; Ubeda, Carles; Clemente, Jose C; Scher, Jose U

Arthritis & rheumatology. 2020 Apr; 72(4):645-657

Perturbed mitochondria-ER contacts in live neurons that model the amyloid pathology of Alzheimer's disease

Martino Adami, Pamela V; Nichtová, Zuzana; Weaver, David B; Bartok, Adam; Wisniewski, Thomas; Jones, Drew R; Do Carmo, Sonia; Castaño, Eduardo M; Cuello, A Claudio; Hajnóczky, György; Morelli, Laura

Journal of cell science. 2019 10 22; 132(20):

Adipocyte-derived lipids mediate melanoma progression via FATP proteins

Zhang, Maomao; Di Martino, Julie S; Bowman, Robert L; Campbell, Nathaniel R; Baksh, Sanjeethan C; Simon-Vermot, Theresa; Kim, Isabella S; Haldeman, Pearce; Mondal, Chandrani; Yong-Gonzalez, Vladimir; Abu-Akeel, Mohsen; Merghoub, Taha; Jones, Drew R; Zhu, Xiphias Ge; Arora, Arshi; Ariyan, Charlotte E; Birsoy, Kivanc; Wolchok, Jedd D; Panageas, Katherine S; Hollmann, Travis J; Bravo-Cordero, Jose Javier; White, Richard M

Cancer discovery. 2018 Aug; 8(8):1006-1025

Isotope Labeling-Assisted Evaluation of Hydrophilic and Hydrophobic Liquid Chromatograph-Mass Spectrometry for Metabolomics Profiling

Xie, Boer; Wang, Yuanyuan; Jones, Drew R; Dey, Kaushik Kumar; Wang, Xusheng; Li, Yuxin; Cho, Ji-Hoon; Shaw, Timothy I; Tan, Haiyan; Peng, Junmin

Analytical chemistry. 2018 Jul 17; 90(14):8538-8545

Target-Decoy-Based False Discovery Rate Estimation for Large-Scale Metabolite Identification

Wang, Xusheng; Jones, Drew R; Shaw, Timothy I; Cho, Ji-Hoon; Wang, Yuanyuan; Tan, Haiyan; Xie, Boer; Zhou, Suiping; Li, Yuxin; Peng, Junmin

Journal of proteome research. 2018 Jul 06; 17(7):2328-2334

See All Publications (20)