Einar M. Sigurdsson

Einar M. Sigurdsson, PhD

Neuroscience Institute

Professor, Department of Neuroscience and Physiology

Professor, Department of Psychiatry

Keywords
pathogenesis , Alzheimer's disease, prion diseases, type-2 diabetes, immunology, molecular, cellular, & translational neuroscience, systems, cognitive, & computational neuroscience, diagnosis, therapy, Parkinson's disease, Neurodegeneration, Neurodegenerative diseases, Protein conformational disorders, imaging
Summary

My current research focuses on pathogenesis, therapy and diagnosis for age-related degenerative diseases, in particular Alzheimer's and more recently Parkinson's disease. In these protein conformational disorders, a normal protein is converted to a pathological form with a high beta-sheet structure. The scientific theme of my work is to study this conformational alteration, its consequences at the molecular- and functional level, and the factors involved in this process.

Phone

212-263-3913

Fax

212-263-2160

Academic office

550 First Avenue, Medical Science Building

Fourth Floor, Room MSB459

New York, NY 10016

Lab Website
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These focus areas and their associated publications are derived from medical subject headings from PubMed.
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Professor, Department of Neuroscience and Physiology

Professor, Department of Psychiatry

PhD from Loyola University

Congdon, Erin E; Lin, Yan; Rajamohamedsait, Hameetha B; Shamir, Dov B; Krishnaswamy, Senthilkumar; Rajamohamedsait, Wajitha J; Rasool, Suhail; Gonzalez, Veronica; Levenga, Josien; Gu, Jiaping; Hoeffer, Charles; Sigurdsson, Einar M

Molecular neurodegeneration. 2016 Aug 30; 11(1):62-62

Sigurdsson, Einar M

Neuro-degenerative diseases. 2016; 16(1-2):34-38

Pedersen, Jan Torleif; Sigurdsson, Einar M

Trends in molecular medicine. 2015 Jun; 21(6):394-402

Krishnaswamy, Senthilkumar; Lin, Yan; Rajamohamedsait, Wajitha J; Rajamohamedsait, Hameetha B; Krishnamurthy, Pavan; Sigurdsson, Einar M

Journal of neuroscience. 2014 Dec 10; 34(50):16835-16850

Congdon, Erin E; Gu, Jiaping; Sait, Hameetha B R; Sigurdsson, Einar M

Journal of biological chemistry. 2013 Dec 06; 288(49):35452-35465

Gu, Jiaping; Congdon, Erin E; Sigurdsson, Einar M

Journal of biological chemistry. 2013 Nov 15; 288(46):33081-33095

Levenga, Josien; Krishnamurthy, Pavan; Rajamohamedsait, Hameetha; Wong, Helen; Franke, Thomas F; Cain, Peter; Sigurdsson, Einar M; Hoeffer, Charles A

Acta neuropathologica communications. 2013 Jul 11; 1:34-34

Bertrand, Anne; Khan, Umer; Hoang, Dung M; Novikov, Dmitry S; Krishnamurthy, Pavan; Rajamohamed Sait, Hameetha B; Little, Benjamin W; Sigurdsson, Einar M; Wadghiri, Youssef Z

Neuroimage. 2013 Jan 01; 64:693-702