Einar M. Sigurdsson

Einar M. Sigurdsson, PhD

Neuroscience Institute

Professor, Department of Neuroscience and Physiology

Professor, Department of Psychiatry

pathogenesis , Alzheimer's disease, prion diseases, type-2 diabetes, immunology, molecular, cellular, & translational neuroscience, systems, cognitive, & computational neuroscience, diagnosis, therapy, Parkinson's disease, Neurodegeneration, Neurodegenerative diseases, Protein conformational disorders, imaging

My current research focuses on pathogenesis, therapy and diagnosis for age-related degenerative diseases, in particular Alzheimer's and more recently Parkinson's disease. In these protein conformational disorders, a normal protein is converted to a pathological form with a high beta-sheet structure. The scientific theme of my work is to study this conformational alteration, its consequences at the molecular- and functional level, and the factors involved in this process.





Academic office

550 First Avenue, Medical Science Building

Fourth Floor, Room MSB459

New York, NY 10016

Lab Website
Is this your profile?
These focus areas and their associated publications are derived from medical subject headings from PubMed.
represents one publication

Professor, Department of Neuroscience and Physiology

Professor, Department of Psychiatry

PhD from Loyola University

Congdon, Erin E; Lin, Yan; Rajamohamedsait, Hameetha B; Shamir, Dov B; Krishnaswamy, Senthilkumar; Rajamohamedsait, Wajitha J; Rasool, Suhail; Gonzalez, Veronica; Levenga, Josien; Gu, Jiaping; Hoeffer, Charles; Sigurdsson, Einar M

Molecular neurodegeneration. 2016 Aug 30; 11(1):62-62

Sigurdsson, Einar M

Neuro-degenerative diseases. 2016; 16(1-2):34-38

Pedersen, Jan Torleif; Sigurdsson, Einar M

Trends in molecular medicine. 2015 Jun; 21(6):394-402

Krishnaswamy, Senthilkumar; Lin, Yan; Rajamohamedsait, Wajitha J; Rajamohamedsait, Hameetha B; Krishnamurthy, Pavan; Sigurdsson, Einar M

Journal of neuroscience. 2014 Dec 10; 34(50):16835-16850

Congdon, Erin E; Gu, Jiaping; Sait, Hameetha B R; Sigurdsson, Einar M

Journal of biological chemistry. 2013 Dec 06; 288(49):35452-35465

Gu, Jiaping; Congdon, Erin E; Sigurdsson, Einar M

Journal of biological chemistry. 2013 Nov 15; 288(46):33081-33095

Levenga, Josien; Krishnamurthy, Pavan; Rajamohamedsait, Hameetha; Wong, Helen; Franke, Thomas F; Cain, Peter; Sigurdsson, Einar M; Hoeffer, Charles A

Acta neuropathologica communications. 2013 Jul 11; 1:34-34

Bertrand, Anne; Khan, Umer; Hoang, Dung M; Novikov, Dmitry S; Krishnamurthy, Pavan; Rajamohamed Sait, Hameetha B; Little, Benjamin W; Sigurdsson, Einar M; Wadghiri, Youssef Z

Neuroimage. 2013 Jan 01; 64:693-702