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Erin E. Congdon

Erin E. Congdon, PhD

Research Assistant Professor, Department of Neuroscience and Physiology

Positions

Research Assistant Professor, Department of Neuroscience and Physiology at NYU Grossman School of Medicine

Graduate Education

PhD from Ohio State University

Phone

212-263-2168

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Academic office

550 First Avenue

Fourth Floor

New York, NY 10016

Single domain antibodies targeting pathological tau protein: Influence of four IgG subclasses on efficacy and toxicity

Congdon, Erin E; Pan, Ruimin; Jiang, Yixiang; Sandusky-Beltran, Leslie A; Dodge, Andie; Lin, Yan; Liu, Mengyu; Kuo, Min-Hao; Kong, Xiang-Peng; Sigurdsson, Einar M

EBioMedicine. 2022 Sep 10; 84:104249

Targeting tau only extracellularly is likely to be less efficacious than targeting it both intra- and extracellularly

Congdon, Erin E; Jiang, Yixiang; Sigurdsson, Einar M

Seminars in cell & developmental biology. 2022 Jun; 126:125-137

Increased neuronal activity in motor cortex reveals prominent calcium dyshomeostasis in tauopathy mice

Wu, Qian; Bai, Yang; Li, Wei; Congdon, Erin E; Liu, Wenke; Lin, Yan; Ji, Changyi; Gan, Wen-Biao; Sigurdsson, Einar M

Neurobiology of disease. 2021 Jan; 147:105165

Dynamics of Internalization and Intracellular Interaction of Tau Antibodies and Human Pathological Tau Protein in a Human Neuron-Like Model

Shamir, Dov B.; Deng, Yan; Wu, Qian; Modak, Swananda; Congdon, Erin E.; Sigurdsson, Einar M.

Frontiers in neurology. 2020; 11:

Tau antibody chimerization alters its charge and binding, thereby reducing its cellular uptake and efficacy

Congdon, Erin E; Chukwu, Jessica E; Shamir, Dov B; Deng, Jingjing; Ujla, Devyani; Sait, Hameetha B R; Neubert, Thomas A; Kong, Xiang-Peng; Sigurdsson, Einar M

EBioMedicine. 2019 Apr; 42:157-173

Structural characterization of monoclonal antibodies targeting C-terminal Ser404 region of phosphorylated tau protein

Chukwu, Jessica E; Congdon, Erin E; Sigurdsson, Einar M; Kong, Xiang-Peng

mAbs : monoclonal antibodies. 2019 Feb 22; 1-12

Tau-targeting therapies for Alzheimer disease

Congdon, Erin E; Sigurdsson, Einar M

Nature reviews. Neurology. 2018 Jul; 14(7):399-415

Affinity of Tau antibodies for solubilized pathological Tau species but not their immunogen or insoluble Tau aggregates predicts in vivo and ex vivo efficacy

Congdon, Erin E; Lin, Yan; Rajamohamedsait, Hameetha B; Shamir, Dov B; Krishnaswamy, Senthilkumar; Rajamohamedsait, Wajitha J; Rasool, Suhail; Gonzalez, Veronica; Levenga, Josien; Gu, Jiaping; Hoeffer, Charles; Sigurdsson, Einar M

Molecular neurodegeneration. 2016 08 30; 11(1):62

See All Publications (25)