Gergely Rona

Gergely Rona, PhD

Adjunct Assistant Professor, Department of Biochemistry and Molecular Pharmacology

Summary

We are investigating how cells maintain their genomic integrity. By using genetic, biochemical, and proteomic approaches, we unravel molecular mechanisms to gain a better understanding of diseases. We work towards providing the foundation for innovative, novel therapeutic approaches.

Is this your profile?
Edit profile

Positions

Adjunct Assistant Professor, Department of Biochemistry and Molecular Pharmacology at NYU Grossman School of Medicine

Graduate Education

PhD from Lorand Eotvos University

Postdoctoral Training

NYU Grossman School of Medicine, Lab of Michele Pagano

ZC3H4 safeguards genome integrity by preventing transcription-replication conflicts at noncoding RNA loci

Frey, Yann; Goehring, Liana; Haj, Majd; Rona, Gergely; Fijen, Carel; Pagano, Michele; Huang, Tony T; Rothenberg, Eli; Ziv, Yael; Shiloh, Yosef

Science advances. 2025 Jun 20; 11(25):eadt8346

Nucleoporins cooperate with Polycomb silencers to promote transcriptional repression and repair at DNA double-strand breaks

Song, Hongseon; Bae, Yubin; Kim, Sangin; Deascanis, Dante; Lee, Yujin; Rona, Gergely; Lane, Ethan; Lee, Seo-Yeoung; Kim, Su-Jung; Pagano, Michele; Myung, Kyungjae; Kee, Younghoon

Proceedings of the National Academy of Sciences of the United States of America. 2025 Jun 03; 122(22):e2415069122

Stabilization of GTSE1 by cyclin D1-CDK4/6-mediated phosphorylation promotes cell proliferation with implications for cancer prognosis

García-Vázquez, Nelson; González-Robles, Tania J; Lane, Ethan; Spasskaya, Daria; Zhang, Qingyue; Kerzhnerman, Marc A; Jeong, YeonTae; Collu, Marta; Simoneschi, Daniele; Ruggles, Kelly V; Róna, Gergely; Kaisari, Sharon; Pagano, Michele

eLife. 2025 Apr 24; 13:

Stabilization of GTSE1 by cyclin D1-CDK4/6 promotes cell proliferation: relevance in cancer prognosis

García-Vázquez, Nelson; González-Robles, Tania J; Lane, Ethan; Spasskaya, Daria; Zhang, Qingyue; Kerzhnerman, Marc; Jeong, YeonTae; Collu, Marta; Simoneschi, Daniele; Ruggles, Kelly V; Rona, Gergely; Pagano, Michele; Kaisari, Sharon

bioRxiv.org : the preprint server for biology. 2025 Jan 23;

Recognition of BACH1 quaternary structure degrons by two F-box proteins under oxidative stress

Cao, Shiyun; Garcia, Sheena Faye; Shi, Huigang; James, Ellie I; Kito, Yuki; Shi, Hui; Mao, Haibin; Kaisari, Sharon; Rona, Gergely; Deng, Sophia; Goldberg, Hailey V; Ponce, Jackeline; Ueberheide, Beatrix; Lignitto, Luca; Guttman, Miklos; Pagano, Michele; Zheng, Ning

Cell. 2024 Dec 26; 187(26):7568-7584.e22

CDK-independent role of D-type cyclins in regulating DNA mismatch repair

Rona, Gergely; Miwatani-Minter, Bearach; Zhang, Qingyue; Goldberg, Hailey V; Kerzhnerman, Marc A; Howard, Jesse B; Simoneschi, Daniele; Lane, Ethan; Hobbs, John W; Sassani, Elizabeth; Wang, Andrew A; Keegan, Sarah; Laverty, Daniel J; Piett, Cortt G; Pongor, Lorinc S; Xu, Miranda Li; Andrade, Joshua; Thomas, Anish; Sicinski, Piotr; Askenazi, Manor; Ueberheide, Beatrix; Fenyö, David; Nagel, Zachary D; Pagano, Michele

Molecular cell. 2024 Apr 04; 84(7):1224-1242.e13

Visualizing Single-Stranded DNA Foci in the G1 Phase of the Cell Cycle

Zhang, Qingyue; Kerzhnerman, Marc A; García-Vázquez, Nelson; Rona, Gergely

Journal of visualized experiments : JoVE. 2023 Dec 22; (202):

A noncanonical function of SKP1 regulates the switch between autophagy and unconventional secretion

Li, Jie; Krause, Gregory J; Gui, Qi; Kaushik, Susmita; Rona, Gergely; Zhang, Qingyue; Liang, Feng-Xia; Dhabaria, Avantika; Anerillas, Carlos; Martindale, Jennifer L; Vasilyev, Nikita; Askenazi, Manor; Ueberheide, Beatrix; Nudler, Evgeny; Gorospe, Myriam; Cuervo, Ana Maria; Pagano, Michele

Science advances. 2023 Oct 13; 9(41):eadh1134

See All Publications (38)