Gergely Rona

Gergely Rona, PhD

Adjunct Assistant Professor, Department of Biochemistry and Molecular Pharmacology

Summary

We are investigating how cells maintain their genomic integrity. By using genetic, biochemical, and proteomic approaches, we unravel molecular mechanisms to gain a better understanding of diseases. We work towards providing the foundation for innovative, novel therapeutic approaches.

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Positions

Adjunct Assistant Professor, Department of Biochemistry and Molecular Pharmacology at NYU Grossman School of Medicine

Graduate Education

PhD from Lorand Eotvos University

Postdoctoral Training

NYU Grossman School of Medicine, Lab of Michele Pagano

Recognition of BACH1 quaternary structure degrons by two F-box proteins under oxidative stress

Cao, Shiyun; Garcia, Sheena Faye; Shi, Huigang; James, Ellie I; Kito, Yuki; Shi, Hui; Mao, Haibin; Kaisari, Sharon; Rona, Gergely; Deng, Sophia; Goldberg, Hailey V; Ponce, Jackeline; Ueberheide, Beatrix; Lignitto, Luca; Guttman, Miklos; Pagano, Michele; Zheng, Ning

Cell. 2024 Dec 26; 187(26):7568-7584.e22

Stabilization of GTSE1 by cyclin D1-CDK4/6 promotes cell proliferation: relevance in cancer prognosis

García-Vázquez, Nelson; González-Robles, Tania J; Lane, Ethan; Spasskaya, Daria; Zhang, Qingyue; Kerzhnerman, Marc; Jeong, YeonTae; Collu, Marta; Simoneschi, Daniele; Ruggles, Kelly V; Rona, Gergely; Pagano, Michele; Kaisari, Sharon

bioRxiv.org : the preprint server for biology. 2024 Jun 27;

CDK-independent role of D-type cyclins in regulating DNA mismatch repair

Rona, Gergely; Miwatani-Minter, Bearach; Zhang, Qingyue; Goldberg, Hailey V; Kerzhnerman, Marc A; Howard, Jesse B; Simoneschi, Daniele; Lane, Ethan; Hobbs, John W; Sassani, Elizabeth; Wang, Andrew A; Keegan, Sarah; Laverty, Daniel J; Piett, Cortt G; Pongor, Lorinc S; Xu, Miranda Li; Andrade, Joshua; Thomas, Anish; Sicinski, Piotr; Askenazi, Manor; Ueberheide, Beatrix; Fenyö, David; Nagel, Zachary D; Pagano, Michele

Molecular cell. 2024 Apr 04; 84(7):1224-1242.e13

Visualizing Single-Stranded DNA Foci in the G1 Phase of the Cell Cycle

Zhang, Qingyue; Kerzhnerman, Marc A; García-Vázquez, Nelson; Rona, Gergely

Journal of visualized experiments : JoVE. 2023 Dec 22; (202):

A noncanonical function of SKP1 regulates the switch between autophagy and unconventional secretion

Li, Jie; Krause, Gregory J; Gui, Qi; Kaushik, Susmita; Rona, Gergely; Zhang, Qingyue; Liang, Feng-Xia; Dhabaria, Avantika; Anerillas, Carlos; Martindale, Jennifer L; Vasilyev, Nikita; Askenazi, Manor; Ueberheide, Beatrix; Nudler, Evgeny; Gorospe, Myriam; Cuervo, Ana Maria; Pagano, Michele

Science advances. 2023 Oct 13; 9(41):eadh1134

A membrane-associated MHC-I inhibitory axis for cancer immune evasion

Chen, Xufeng; Lu, Qiao; Zhou, Hua; Liu, Jia; Nadorp, Bettina; Lasry, Audrey; Sun, Zhengxi; Lai, Baoling; Rona, Gergely; Zhang, Jiangyan; Cammer, Michael; Wang, Kun; Al-Santli, Wafa; Ciantra, Zoe; Guo, Qianjin; You, Jia; Sengupta, Debrup; Boukhris, Ahmad; Zhang, Hongbing; Liu, Cheng; Cresswell, Peter; Dahia, Patricia L M; Pagano, Michele; Aifantis, Iannis; Wang, Jun

Cell. 2023 Aug 31; 186(18):3903-3920.e21

CDT1, a licensing factor that limits rereplication

Rona, Gergely; Pagano, Michele

Molecular cell. 2023 Jan 05; 83(1):1-3

The NSP14/NSP10 RNA repair complex as a Pan-coronavirus therapeutic target

Rona, Gergely; Zeke, Andras; Miwatani-Minter, Bearach; de Vries, Maren; Kaur, Ramanjit; Schinlever, Austin; Garcia, Sheena Faye; Goldberg, Hailey V; Wang, Hui; Hinds, Thomas R; Bailly, Fabrice; Zheng, Ning; Cotelle, Philippe; Desmaële, Didier; Landau, Nathaniel R; Dittmann, Meike; Pagano, Michele

Cell death & differentiation. 2022 Feb; 29(2):285-292

See All Publications (35)