Hector Arciniega

Hector Arciniega, PhD

Assistant Professor, Department of Rehabilitation Medicine

Keywords
neuroimaging, brain injury, contact sports, health disparities, maternal health, concussion
Summary

My research centers on three critical areas of inquiry that are intricately linked within the field of neuroscience. First and foremost, I explore the long-term consequences of repetitive head impacts experienced by athletes in contact and collision sports. This line of investigation is vital for gaining a comprehensive understanding of not only concussive injuries but also the cumulative effects of repeated head impacts on the brain, cognition, and emotional health. Using advanced neuroimaging techniques, I assess alterations in brain structure and function, which provide valuable insights into potential cognitive decline, mood disorders, and other mental health challenges that may develop over time. A key focus of my research is the identification of in vivo biomarkers for detecting Chronic Traumatic Encephalopathy (CTE), a condition that poses significant risks to athletes and underscores the urgent need for early detection and intervention.

Second, I examine how social determinants of health and health disparities contribute to the incidence of head injuries, recovery processes, and long-term outcomes. By considering socioeconomic status, access to healthcare, and community resources, I aim to uncover the broader influences that shape health outcomes in diverse populations. Understanding these factors is crucial for developing targeted interventions and public health strategies that address these disparities, ultimately leading to improved care and outcomes for all individuals, regardless of their background.

Third, my research explores the consequences of head injuries during and after pregnancy, focusing on both the parent and the developing fetus. I am particularly interested in how maternal head trauma may affect fetal development and outcomes, an area that has not been extensively studied but carries significant implications for maternal and child health. By investigating the relationship between maternal brain health and pregnancy outcomes, I plan to shed light on the importance of safeguarding both maternal well-being and fetal development in clinical settings.

At the core of my research program is the application of state-of-the-art neuroimaging techniques. These advanced methodologies provide comprehensive insights into the intricate repercussions of head injuries, allowing me to understand better the underlying mechanisms at play. By combining neuroimaging data with behavioral assessments and clinical evaluations, I strive to build a holistic understanding of the effects of head injuries. Ultimately, my work aims to contribute not only to scientific knowledge but also to the development of effective prevention and intervention strategies that can enhance the quality of life for individuals affected by brain injuries. 

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Director, Research, Concussion Center

PhD from University of Nevada, Reno

Harvard Medical School, Psychiatry Neuroimaging Laboratory

Arciniega, Hector; Jung, Leonard B; Tuz-Zahra, Fatima; Tripodis, Yorghos; John, Omar; Kim, Nicholas; Carrington, Holly W; Knyazhanskaya, Evdokiya E; Chamaria, Arushi; Breedlove, Katherine; Wiegand, Tim L; Daneshvar, Daniel; Billah, Tashrif; Pasternak, Ofer; Coleman, Michael J; Adler, Charles H; Bernick, Charles; Balcer, Laura J; Alosco, Michael L; Lin, Alexander P; Koerte, Inga K; Cummings, Jeffrey L; Reiman, Eric M; Stern, Robert A; Bouix, Sylvain; Shenton, Martha E; ,

Neurology. Clinical practice. 2024 Oct; 14(5):e200324

Szekely, Brian; Stearns, Jared; Mirmajlesi, Anya S; Folkerth, Rebecca D; Bouix, Sylvain; Daneshvar, Daniel H; Adler, Charles H; Bernick, Charles; Balcer, Laura J; Cummings, Jeffrey L; Reiman, Eric M; Stern, Robert A; Shenton, Martha E; Rushmore, Richard J; Arciniega, Hector; ,

Alzheimer's & dementia : the journal of the Alzheimer's Association. 2026 Sep; 22(9):e71764

Wiegand, Tim L T; Rubinski, Anna; Jung, Leonard B; Franzmeier, Nicolai; Arciniega, Hector; Ravanfar, Parsa; Dewenter, Anna; Alosco, Michael L; Tripodis, Yorghos; Su, Yi; Protas, Hillary; Lin, Alexander P; Pasternak, Ofer; Chen, Kewei; Coleman, Michael J; Bouix, Sylvain; Adler, Charles H; Balcer, Laura J; Bernick, Charles; Cummings, Jeffrey L; Stern, Robert A; Reiman, Eric M; Shenton, Martha E; Ewers, Michael; Koerte, Inga K; ,

Alzheimer's & Dementia. 2026 Jun; 22(6):e71503

Olivera, Anlys; Pagnotta, Geraldine; Sproul, Mara; Phillips, Laura; Syed, Nuha; Drattell, Julia D; Juanito, Ma Victoria Castaneda; Fay, Jennifer; Denham, Teresa V; Serrano, Liliana; Zhao, Jiangyue; Parkin, Catherine A; Datta, Shae; Im, Brian S; Cardone, Dennis; Hainline, Brian; Flanagan, Steven; Galetta, Steven L; Balcer, Laura J; Arciniega, Hector

Neurology. Clinical practice. 2026 Apr; 16(2):e200598

Pablo, J N; Kemmelmeier, L L; Arciniega, H; Shires, J; Torrens, W A; Berryhill, M E; Haigh, S M

European journal of neuroscience. 2026 Apr; 63(7):e70494

Wiegand, Tim L T; Pankatz, Lara; Arciniega, Hector; Jung, Leonard B; Tuz-Zahra, Fatima; Bouix, Sylvain; Lubeck, Haley; Rojczyk, Philine; Schuhmacher, Luisa S; Buring, Janna; Katz, Douglas I; Tripodis, Yorghos; Pasternak, Ofer; Cetin-Karayumak, Suheyla; Rathi, Yogesh; Adler, Charles H; McKee, Ann C; Balcer, Laura J; Bernick, Charles; Coleman, Michael J; Colasurdo, Elizabeth A; Lin, Alexander P; Peskind, Elaine R; Ashton, Nicholas J; Blennow, Kaj; Zetterberg, Henrik; Alosco, Michael L; Cummings, Jeffrey L; Reiman, Eric M; Stern, Robert A; Shenton, Martha E; Koerte, Inga K; ,

Journal of neurotrauma. 2026 Feb; 43(3-4):224-235

Arciniega, Hector; Wickham, Alana; Szekely, Brian; Kim, Nicholas; Cho, Kang I; Carrington, Holly; Knyazhanskaya, Evdokiya E; John, Omar; Jung, Leonard B; Breedlove, Katherine; Mirmajlesi, Anya S; Stearns, Jared; Rushmore, Richard Jarrett; Daneshvar, Daniel H; Wiegand, Tim L T; Billah, Tashrif; Pasternak, Ofer; Cetin-Karayumak, Suheyla; Rathi, Yogesh; Coleman, Michael J; Adler, Charles H; Bernick, Charles; Balcer, Laura J; Im, Brian S; Datta, Shae; Alosco, Michael L; Koerte, Inga K; Lin, Alexander P; Cummings, Jeffrey L; Reiman, Eric M; Stern, Robert A; Shenton, Martha E; Bouix, Sylvain; ,

Brain communications. 2026 Jun; 8(3):fcag195

Heller, Carina; Christensen, Erynn; Murata, Elle M; Petersen, Nicole; Casto, Kathleen; Datta, Shae; Larsen, Bart; Arciniega, Hector

Nature medicine. 2025 Nov; 31(11):3598-3600