Helen E. Scharfman

Helen E. Scharfman, PhD

Professor, Department of Child and Adolescent Psychiatry

Professor, Department of Neuroscience

Professor, Department of Psychiatry

Keywords
hippocampus and parahippocampal areas, their role in normal function and their contribution to neurological disorders and mental illness, neurotrophins (BDNF)and neuronal plasticity , neurogenesis in the dentate gyrus , mechanisms controlling neuronal excitability; seizures; epilepsy, neuronal modulation by reproductive steroids, brain and spinal cord injury; neuroprotection, imaging, molecular, cellular, & translational neuroscience, systems, cognitive, & computational neuroscience

Phone

845-398-5427

Lab Website
Scharfman Lab
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Positions

Professor, Department of Child and Adolescent Psychiatry at NYU Grossman School of Medicine

Professor, Department of Neuroscience at NYU Grossman School of Medicine

Professor, Department of Psychiatry at NYU Grossman School of Medicine

Shining Light on the Neuropathology of Temporal Lobe Epilepsy

Scharfman, Helen E

Epilepsy currents. 2026 Apr 20; 15357597261444605

Wondering About Wandering

Scharfman, Helen E

Epilepsy currents. 2026 Feb 19; 15357597261423663

The cholinergic system exerts opposing effects on memory at different stages of disease progression in Alzheimer's and Down syndrome model systems

Lisgaras, Christos Panagiotis; Scharfman, Helen E

Alzheimer's & Dementia. 2026 Feb; 22(2):e71154

Chemogenetic activation of hippocampal area CA2 promotes acute and chronic seizures in a mouse model of epilepsy

LaFrancois, John J; Kennedy, Meghan; Rathod, Monarchsinh; Santoro, Bina; Lisgaras, Christos Panagiotis; Siegelbaum, Steven A; Scharfman, Helen E

Neurobiology of disease. 2026 Jan 03; 107256

Restoration of sFRP3 preserves the neural stem cell pool and spatial discrimination ability in a mouse model of Alzheimer's disease

Fu, Chia-Hsuan; Park, Jin; Tosi, Umberto; Blanco, Francisco A; Silva-Pérez, Manuel; Muralidharan, Kavitha; You, Jason C; Lee, Minjung; Stephens, Gabriel S; Zhang, Xiaohong; Zheng, Yi; Scharfman, Helen; Tolias, Kimberley F; Chin, Jeannie

Journal of neuroscience. 2025 Dec 03; 45(49):

Sweetens the Pot" for Drug-Resistant Epilepsy-With an After Taste"> Clioquinol "Sweetens the Pot" for Drug-Resistant Epilepsy-With an After Taste

Scharfman, Helen E

Epilepsy currents. 2025 Nov 19; 15357597251387418

Opposing interictal dynamics in Alzheimer's disease and epilepsy

Lisgaras, Christos Panagiotis; Scharfman, Helen E

Progress in neurobiology (1973). 2025 Nov 03; 102844

Getting STAT-isfaction

Scharfman, Helen E

Epilepsy currents. 2025 Jul 17; 15357597251352993

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