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Jef D. Boeke

Jef D. Boeke, PhD

Sol and Judith Bergstein Director, Institute of System Genetics

Professor, Department of Biochemistry and Molecular Pharmacology

Keywords
cancer, computational biology, genome integrity, genomics, microbiology, pharmacology, stem cell biology, systems biology, yeast, retrotransposon

Academic office

435 East 30th Street, Science Building

9th Floor, Room 917

New York, NY 10016

Lab Website
Boeke Lab
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Positions

Professor, Department of Biochemistry and Molecular Pharmacology at NYU Grossman School of Medicine

Sol and Judith Bergstein Director, Institute of System Genetics

Graduate Education

PhD from Rockefeller University

LINE-1 retrotransposon expression in cancerous, epithelial and neuronal cells revealed by 5' single-cell RNA-Seq

McKerrow, Wilson; Kagermazova, Larisa; Doudican, Nicole; Frazzette, Nicholas; Kaparos, Efiyenia Ismini; Evans, Shane A; Rocha, Azucena; Sedivy, John M; Neretti, Nicola; Carucci, John; Boeke, Jef D; Fenyö, David

Nucleic acids research. 2023 Mar 21; 51(5):2033-2045

Two differentially stable rDNA loci coexist on the same chromosome and form a single nucleolus

Lazar-Stefanita, Luciana; Luo, Jingchuan; Haase, Max A B; Zhang, Weimin; Boeke, Jef D

Proceedings of the National Academy of Sciences of the United States of America (PNAS). 2023 Feb 28; 120(9):e2219126120

DASH/Dam1 complex mutants stabilize ploidy in histone-humanized yeast by weakening kinetochore-microtubule attachments

Haase, Max A B; Ólafsson, Guðjón; Flores, Rachel L; Boakye-Ansah, Emmanuel; Zelter, Alex; Dickinson, Miles Sasha; Lazar-Stefanita, Luciana; Truong, David M; Asbury, Charles L; Davis, Trisha N; Boeke, Jef D

EMBO journal. 2023 Jan 18; e112600

Resurrecting essential amino acid biosynthesis in mammalian cells

Trolle, Julie; McBee, Ross M; Kaufman, Andrew; Pinglay, Sudarshan; Berger, Henri; German, Sergei; Liu, Liyuan; Shen, Michael J; Guo, Xinyi; Martin, J Andrew; Pacold, Michael E; Jones, Drew R; Boeke, Jef D; Wang, Harris H

eLife. 2022 Sep 27; 11:

Systems genomics in age-related macular degeneration

den Hollander, Anneke I; Mullins, Robert F; Orozco, Luz D; Voigt, Andrew P; Chen, Hsu-Hsin; Strunz, Tobias; Grassmann, Felix; Haines, Jonathan L; Kuiper, Jonas J W; Tumminia, Santa J; Allikmets, Rando; Hageman, Gregory S; Stambolian, Dwight; Klaver, Caroline C W; Boeke, Jef D; Chen, Hao; Honigberg, Lee; Katti, Suresh; Frazer, Kelly A; Weber, Bernhard H F; Gorin, Michael B

Experimental eye research. 2022 Sep 12; 109248

Karyotype engineering reveals spatio-temporal control of replication firing and gene contacts

Lazar-Stefanita, Luciana; Luo, Jingchuan; Montagne, Remi; Thierry, Agnes; Sun, Xiaoji; Mercy, Guillaume; Mozziconacci, Julien; Koszul, Romain; Boeke, Jef D

Cell genomics. 2022 Aug 10; 2(8):None

Synthetic regulatory reconstitution reveals principles of mammalian Hox cluster regulation

Pinglay, Sudarshan; Bulajić, Milica; Rahe, Dylan P; Huang, Emily; Brosh, Ran; Mamrak, Nicholas E; King, Benjamin R; German, Sergei; Cadley, John A; Rieber, Lila; Easo, Nicole; Lionnet, Timothée; Mahony, Shaun; Maurano, Matthew T; Holt, Liam J; Mazzoni, Esteban O; Boeke, Jef D

Science. 2022 07; 377(6601):eabk2820

A conditional counterselectable Piga knockout in mouse embryonic stem cells for advanced genome writing applications

Zhang, Weimin; Brosh, Ran; McCulloch, Laura H; Zhu, Yinan; Ashe, Hannah; Ellis, Gwen; Camellato, Brendan R; Kim, Sang Yong; Maurano, Matthew T; Boeke, Jef D

iScience. 2022 Jun 17; 25(6):104438

See All Publications (447)

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