Jennifer Mcneely

Jennifer Mcneely, MD

Associate Professor, Department of Population Health

Associate Professor, Department of Medicine

Summary

Personal Statement

As a clinician investigator at NYU School of Medicine, in the Dept. of Population Health and Dept. of Medicine, my research focuses on the implications of substance use for individuals and health systems, and on improving the identification and treatment of addiction in general medical settings.  In 2010 I received a NIDA K23 career development award to study patient self-administered substance use screening in primary care settings. Following on that award, I received a NIDA R34 to develop and test a technology-assisted approach to integrating screening and brief intervention into medical visits.  I was Co-Lead Investigator of a multi-site NIDA Clinical Trials Network (CTN) study (CTN 0059) that developed and validated a brief substance use screening instrument (TAPS Tool).  Currently, I am Lead Investigator of a NIDA CTN study (CTN 0062-Ot) that seeks to integrate the NIDA Common Data Elements into electronic health records in large health systems.  My prior work has included the use of large public health data sets to estimate the population prevalence of opioid use disorder, policy research on models of opioid maintenance treatment and clinical research on an HIV prevention intervention in a methadone maintenance treatment program.  My research is informed by my clinical practice as a primary care and addiction medicine physician at Bellevue Hospital (part of the NYC Health and Hospitals system).

  1. McNeely J, Gourevitch MN, Paone D, Shah S, Wright S, Heller D.  (2012). Estimating the Prevalence of Illicit Opioid Use in New York City Using Multiple Data Sources.  BMC Public Health,12:443. PMCID: PMC3416644.
  2. McNeely J, Strauss SM, Saitz R, Cleland CM, Palamar JJ, Rotrosen J, Gourevitch MN. (2015). A brief patient self-administered substance use screening tool for primary care: two-site validation study of the Substance Use Brief Screen (SUBS).  The American Journal of Medicine, 128(7):784:e9-19. PMCID: PMC4475501.
  3. McNeely J, Strauss SM, Rotrosen J, Ramautar A, Gourevitch MN.  (2016). Validation of an audio computer assisted self interview (ACASI) version of the Alcohol, Smoking and Substance Involvement Screening Test (ASSIST) in primary care patients.  Addiction, 111(2): 233-244.  PMCID: PMC4899945
  4. McNeely J, Wu LT, Subramaniam G, Sharma G, Cathers LA, Svikis D, Sleiter L, Russell L, Nordeck C, Sharma A, O'Grady KE, Bouk LB, Cushing C, King J, Wahle A, Schwartz RP. (2016).  Performance of the Tobacco, Alcohol, Prescription Medication, and Other Substance Use (TAPS) Tool for Substance Use Screening in Primary Care Patients. Ann Intern Med,165(10):690-99 PMCID: PMC 5291717.

Positions and Honors

Other Experience and Professional Memberships

2007               American Board of Internal Medicine

2009-Pres      Substance Abuse Interest Group, Society of General Internal Medicine

2010-Pres      Association for Medical Education and Research in Substance Abuse

2011               Treatment Decision Guide Special Interest Group, NIDA Clinical Trials Network

2012-2015     Scientific Review Committee, NYU-HHC CTSI                                             

2012               American Board of Addiction Medicine

2015-2016     Abstract Committee Co-Chair, Association for Medical Education and Research in SubstanceAbuse (AMERSA), 2015 and 2016 annual meetings

2016-2017     Chair of the Executive Committee, 14th Annual conference of the International Network on Brief Interventions for Alcohol and Other Drugs (INEBRIA)

2016-Pres      Member of the Coordinating Committee, International Network on Brief Interventions for Alcohol and Other Drugs (INEBRIA)

Honors and Awards

1994                Phi Beta Kappa, Columbia University, New York

1999                Golding Distinguished Scholar Fellowship, Albert Einstein College of Medicine, New York

2003                Alpha Omega Alpha, Albert Einstein College of Medicine, New York

2009                National Institutes of Health Loan Repayment Program

2010                Michael Saperstein Medical Scholar, NYU Dept. of Medicine

2013                Best Abstract award, Association for Medical Education and Research in Substance Abuse

2014                Best Peer Review award, Substance Abuse

2011-2015       National Institutes of Health Loan Repayment Program

Contribution to Science

  1. Substance use screening tools for use in medical settings.  My research and clinical practice has given me a deep appreciation of the challenges, as well as the benefits, of implementing substance use interventions into medical settings.  Given time pressures and multiple competing priorities, there is a clear need for substance use screening approaches that can fit into existing clinical workflows.  To address this, I have developed a line of research on very brief, validated, patient self-administered screening tools.  Self-administered tools have the potential to save time and staff resources by allowing screening to be completed prior to the medical visit, while also easing the discomfort that patients may have with completing screening face-to-face, and maintaining the fidelity of the screening instrument.  With the support of a NIDA K23 award I developed patient self-administered computer-assisted screening tools that can be completed prior to the medical visit, and validated these tools in primary care patients.  One such instrument is the audio computer assisted self interview (ACASI) version of the World Health Organization’s Alcohol, Smoking, and Substance Involvement Screening Test (ASSIST), which I developed using a mixed methods approach, and then validated in a large population of adult primary care patients. With a second grant from the NYU-HHC CTSI, I led a study to develop and validate a brief 4-item screening tool called the Substance Use Brief Screen (SUBS), and I collaborated with Richard Saitz, MD, MPH, on a two-site study to validate self-administered versions of the widely used single item screening questions for alcohol and drugs.  Based on my expertise in this area, I was then invited to be Co-Lead Investigator of a large multi-site NIDA Clinical Trials Network (CTN) trial (CTN-0059) to develop and validate a streamlined screening and assessment instrument (TAPS Tool).  I led the study at the Bellevue site, which enrolled 534 participants (165% of projected), and was completed 4 months ahead of schedule, and was first author of the primary outcome paper reporting the results of the CTN-0059 validation study in the Annals of Internal Medicine. 
  • McNeely J, Cleland CM, Strauss SM, Palamar JJ, Rotrosen J, Saitz R.  (2015). Validation of self-administered single item screening questions (SISQs) for unhealthy alcohol and drug use in primary care patients.  Journal of General Internal Medicine, 30(12):1757-64.  PMCID: PMC4636560
  • McNeely J, Halkitis PN, Horton A, Khan R, Gourevitch MN.  (2014). How patients understand the term ‘nonmedical use’ of prescription drugs:  insights from cognitive interviews.  Substance Abuse, 35:1, pp. 12-20. PMCID: PMC3942803 
  • Spear SE, Shedlin M, Gilberti B, Fiellin M, McNeely J.  (2015).  Feasibility and acceptability of an audio computer-assisted self-interview version of the Alcohol, Smoking, and Substance Involvement Screening Test (ASSIST) in primary care patients.  Substance Abuse 37(2):299-305.  PMCID: PMC4962999
  • Kumar PC, Cleland CM, Gourevitch MN, Rotrosen J, Strauss S, Russell L, McNeely J. Accuracy of the Audio Computer Assisted Self Interview version of the Alcohol, Smoking and Substance Involvement Screening Test (ACASI ASSIST) for identifying unhealthy substance use and substance use disorders in primary care patients. (2016).  Drug Alcohol Depend, 165(10):690-699.  PMCID: PMC4962996

       2.Integrating substance use disorder treatment into medical care.  My work on screening tools stems from a larger interest in integrating addiction treatment with medical care.  While only a small proportion of individuals with substance use disorders are seen in the specialty addiction treatment setting, they do                have frequent contacts with the health care system.  Health care contacts present an opportunity to provide substance use interventions that can improve population health.   As a pre-medical student, I explored the potential to expand access to opioid maintenance treatment through office-based pharmacotherapy,              and later saw this become a reality with the approval of buprenorphine and the Drug Addiction Treatment Act of 2000.  During my fellowship in Medicine and Public Health Research, I collaborated with the New York City Department of Health and Mental Hygiene (DOHMH) on two projects:  one to author a practice              guideline for primary care practitioners on improving care for patients with substance use, and a second to describe the health burden of illicit opioid use in New York City using large administrative data sets.  I participated in a NIDA working group, led by former Deputy Director of the Office of National Drug Control              Policy A. Thomas McLellan, on addressing addictions using the chronic care model.   I am currently Lead Investigator of a new study in the NIDA Clinical Trials Network (CTN-0062) that is working with two large health care systems to incorporate substance use information into electronic health records.

  • McNeely J, Drucker E, Hartel D, Tuchman E.  (2000). Office-Based Methadone Prescribing:  Acceptance by Inner-City Practitioners in New York.  Journal of Urban Health,77(1):96-102. PMCID: PMC3456609
  • McNeely J, Gourevitch MN, Heller D, Paone D, Lee JD.  (2009). Improving the Health of People Who Use Drugs.  City Health Information, 28(3):21-28.
  • McNeely J, Gourevitch MN, Paone D, Shah S, Wright S, Heller D.  (2012). Estimating the Prevalence of Illicit Opioid Use in New York City Using Multiple Data Sources.  BMC Public Health,12:443. PMCID: PMC3416644.
  • McLellan AT, Starrels JL, Tai B, Gordon A, Brown R, Ghitza U, Gourevitch MN, Stein J, Oros M, Horton T, Linblad R, McNeely J.  (2014). Can substance use disorders be managed using the chronic care model?  Review and recommendations from a NIDA consensus group. Public Health Reviews, 35(2). PMCID: PMC4643942.

      3.Substance use screening in dental clinics.  My interest in utilizing routine health care contacts to improve the health of substance-using populations also led me to explore the potential for incorporating substance use screening into novel settings.  One branch of this work has been to explore screening for                       tobacco, alcohol, and drug use in dental clinics.  Dental providers see a broad proportion of the population, and have regular contact with individuals who may not otherwise visit medical providers. In collaboration with Donna Shelley, MD, MPH, (Co-Investigator on the proposed study), I conducted a survey of                       dentists in a practice-based research network, and participated in developing a large national survey to describe dentists’ practices and attitudes regarding addressing substance use as part of routine dental care.

  • McNeely J, Wright S, Matthews AG, Rotrosen J, Shelley D, Buchholz M, Curro FA.  (2013). Substance use screening and interventions in dental clinics:  survey of practice-based research network dentists on current practices, policies, and barriers.  Journal of the American Dental Association,144(6):627-38.  PMCID: 3699308
  • Shelley D, Wright S, McNeely J, Rotrosen J, Feinstein Winitzer R, Pollack H, Abel S, Metsch L. (2012).   Reimbursing Dentists for Smoking Cessation Treatment: Views from dental insurers.  Nicotine and Tobacco Research, 14:1180-6.  PMCID: PMC3457710
  • Jannat-Khah DP, McNeely J, Pereyra MR, Parish C, Pollack HA, Ostroff J, Metsch L, Shelley DR. (2014). Dentists' self-perceived role in offering tobacco cessation services: Results from a nationally representative survey, 2010-2011.  Preventing Chronic Disease, 11:E196.  PMCID: 4222784

      4.Addressing new health challenges in substance use disorder treatment programs.  I have also conducted research within addiction treatment programs on interventions to improve the health of their patient populations.  During medical school, I designed, implemented, and tested an intervention to improve                 access to sterile injecting equipment for patients in a methadone treatment program.   This study was an early formative experience because it introduced me to the challenges and rewards of implementing interventions that are integrated into existing health systems, and thus have potential to be sustained and                   disseminated. Currently, I am working with a geriatrician to characterize the aging methadone maintenance treatment population, and develop interventions to address their needs.

  • McNeely J, Arnsten JA, Gourevitch MN. (2006). Sterile Syringe Access and Disposal among Injection Drug Users Newly Enrolled in Methadone Maintenance Treatment: A cross-sectional survey.  Harm Reduction Journal, 3:8.  PMCID: PMC1402270
  • McNeely J, Arnsten JA, Gourevitch MN. (2006). Improving Access to Sterile Syringes and Safe Syringe Disposal for Injection Drug Users in Methadone Maintenance Treatment.  Journal of Substance Abuse Treatment, 31(1):51-57. 
  • Han BH, Polydorou S, Ferris R, Blaum C, Ross S, McNeely J. (2015). Demographic Trends of Adults in New York City Opioid Treatment Programs - An Aging Population. Substance Use and Misuse, 50(13):1660-7.

      5. Medication for addiction treatment in medical settings.   As a researcher focused on improving population health, I am keenly aware of how under-utilized addiction medications are in medical settings.  With Dr. Joshua Lee and other colleagues in the Division on Tobacco, Alcohol, and Drug Use, I have been                 deeply involved in clinical practice, education, and research that aims to improve and sustain addictions treatment in general health care settings.  As a result of this experience, I was invited to join the NIDA Clinical Decision Support for Opioid Use Disorders Expert Panel and the study that grew out of it (CTN-0076-           Ot), which is developing an electronic health record-integrated  decision support tool to support primary care providers in treating patients with opioid use disorders.  I am a current member of the NYC Department of Health and Mental Hygiene Buprenorphine Advisory Panel, which guides policy and educates                       clinicians to increase the delivery of buprenorphine treatment in NYC. 

  • Lee JD, McNeely J, Grossman E, Vocci F, Fiellin DA. (2014). Clinical case conference:  unobserved ‘home’ induction onto buprenorphine.  Journal of Addiction Medicine, 8(5):309-14. 
  • Lee JD, McDonald R, Grossman E, McNeely J, Laska E, Rotrosen J, Gourevitch MN.  (2015). Opioid treatment at release from jail using extended-release naltrexone:  a pilot proof-of-concept randomized effectiveness trial.  Addiction, 110(6):1008-14.
  • Bhatraju EP, Grossman E, Tofighi B, McNeely J, DiRocco D, Flannery M, Garment A, Goldfeld K, Gourevitch MN, Lee JD. (2017).  Public sector low threshold office-based buprenorphine treatment: outcomes at year 7. Addict Sci Clin Pract, 12(1):7. PMCID: 5331716
  • Accurso AJ, Lee JD, McNeely J (2017). High prevalence of urine tampering in an office-based opioid treatment practice detected by evaluating the norbuprenorphine to buprenorphine ratio. J Subst Abuse Treat, 83:62-67. PMCID– PMC Journal, In Process.

Research Support

Ongoing Research Support

1R34 DA040830-01 - McNeely (PI) -  07/01/2016-06/31/2019 NIH/NIDA                                                                                Leveraging technology to address unhealthy drug use in primary care settings. The proposed study aims to develop and test a new model of integrating substance use screening and brief interventions in primary care settings.  The Substance Use Screening and Intervention Tool (SUSIT) utilizes health information technology to assist primary care providers in addressing unhealthy drug use by providing patient self-administered screening, clinical decision support, and clinical reminders.    5UG1DA013035-14S4 - Nunes and Rotrosen (PI)                                                                    NIH/NIDA                                                        NIDA Clinical Trials Network: Greater New York Node – Supplement CTN-0062-Ot  - 09/01/2015-05/31/2020 A Phased-Implementation Feasibility and Proof-of-Concept Study to Assess Incorporating the NIDA CTN Common Data Elements (CDEs) into the Electronic Health Record (EHR) in Large Primary Care Settings This 4-phase implementation study seeks to incorporate the NIDA CDEs into the EHR in primary care settings.  It aims to develop and implement a strategy for screening, with results entered into the EHR and paired with clinical decision support at the point of care, along with an EHR-integrated system for treatment referrals. Role:  Lead Investigator   CTN-0062-Ot-A1 - 06/01/2017-05/31/2020                                                                                                                                Implementing the Tobacco, Alcohol, Prescription Medication, and Other Substances (TAPS) Tool in rural federally-qualified health centers:  An ancillary study of the CDE-EHR-PC Study. This ancillary study to NIDA CTN-0062-Ot will study the implementation of electronic health record (EHR) integrated screening for substance use in a network of rural federally qualified health centers. Role:  Lead Investigator   R13AA025541 -  McNeely and Shelley (mPI) -  04/10/2017-03/31/2018       NIH/NIAAA and NIDA                                                                Screening and brief intervention at the intersection of research, policy and practice:  Advancing knowledge and meeting new challenges This conference grant proposal is to support an alcohol and drug screening and brief intervention research conference in New York, NY, September 14-15, 2017.  The conference will be the 14th annual meeting of the International Network on Brief Interventions for Alcohol and Other Drugs (INEBRIA). 5R25DA022461-09                                                                 Gourevitch (PI)                                                                                               06/01/2017-05/31/2022 NIH/NIDA                                                                                Substance Abuse Research Education and Training (SARET) The primary goal of this initiative is to design, implement and evaluate a substance abuse research training program for physicians, nurses and dentists that will stimulate participants’ interest in pursuing careers in drug abuse research. Role:  Co-Investigator   Completed Research Support K23 DA030395  -  McNeely (PI) -  09/30/2010-02/29/2016 NIH/NIDA Screening for substance use with computer assisted self interview in primary care The goal of this study is to determine the validity and feasibility of a patient self-administered substance use screening and assessment in primary care.    CTN-0059  -  Schwartz (PI)  -  01/01/2014-08/31/2015 NIH/NIDA CTN                                                                                   The TAPS Tool:  Screen and Brief Assessment Tool Validation Study This study of the NIDA Clinical Trials Network developed and validated a 4-item screen and a two-stage screening and brief assessment tool to screen and assess primary care patients for tobacco, alcohol, prescription drug, and illicit substance use and problems related to their use. Role:  Co-Lead Investigator and Site PI   R25 DA022461 -  Gourevitch (PI)  -  06/01/2012 – 05/31/2017 NIH/NIDA                                                                    Substance Abuse Research Education and Training (SARET) Role:  Co-Investigator
Phone

212-263-4975

Academic office

227 East 30th Street

Seventh Floor

New York, NY 10016

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Associate Professor, Department of Population Health

Associate Professor, Department of Medicine

MD from Albert Einstein College of Medicine

Fellowship, NYU School of Medicine, Department of Medicine, Division of General Internal Medicine

Residency, Brigham and Women's Hospital, Internal Medicine-Primary Care

McNeely, Jennifer; Kumar, Pritika C; Rieckmann, Traci; Sedlander, Erica; Farkas, Sarah; Chollak, Christine; Kannry, Joseph L; Vega, Aida; Waite, Eva A; Peccoralo, Lauren A; Rosenthal, Richard N; McCarty, Dennis; Rotrosen, John

Addiction science & clinical practice. 2018 Apr 09; 13(1):8-8

Geriatric conditions among middle-aged and older adults on methadone maintenance treatment [Meeting Abstract]

Han, B.; Cotton, B.; Polydorou, S.; Blaum, C.; McNeely, J.; Sherman, S.

Journal of the American Geriatrics Society. 2018 APR; 66:S237-S237

Accurso, Anthony J; Lee, Joshua D; McNeely, Jennifer

Journal of substance abuse treatment. 2017 Dec; 83:62-67

Han, Benjamin H; Sherman, Scott E; Link, Alissa R; Wang, Binhuan; McNeely, Jennifer

Journal of substance abuse treatment. 2017 Aug; 79:67-74

Wu, Li-Tzy; McNeely, Jennifer; Subramaniam, Geetha A; Brady, Kathleen T; Sharma, Gaurav; VanVeldhuisen, Paul; Zhu, He; Schwartz, Robert P

Drug & alcohol dependence. 2017 Jul 13; 179:42-46

Bertholet, Nicolas; Daeppen, Jean-Bernard; McNeely, Jennifer; Kushnir, Vlad; Cunningham, John A

Substance abuse. 2017 Jul -0; 38(3):285-291

Gryczynski, Jan; McNeely, Jennifer; Wu, Li-Tzy; Subramaniam, Geetha A; Svikis, Dace S; Cathers, Lauretta A; Sharma, Gaurav; King, Jacqueline; Jelstrom, Eve; Nordeck, Courtney D; Sharma, Anjalee; Mitchell, Shannon G; O'Grady, Kevin E; Schwartz, Robert P

Journal of general internal medicine. 2017 May 26; 32(9):990-996

Tofighi, Babak; Nicholson, Joseph M; McNeely, Jennifer; Muench, Frederick; Lee, Joshua D

Drug & alcohol review. 2017 May 5; 36(4):477-491