Jiehui Deng

Jiehui Deng, PhD

Perlmutter Cancer Center

Research Assistant Professor, Department of Medicine

Positions

Research Assistant Professor, Department of Medicine at NYU Grossman School of Medicine

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Design and Development of DNA Damage Chemical Inducers of Proximity for Targeted Cancer Therapy

Qiu, Tian; Lee, Yeuan Ting; Dwyer, Brendan G; Tan, Yi Jer; Chen, Ting; Romero, Bryan A; Wang, Yanlan; Deng, Jiehui; Zhang, Tinghu; Crabtree, Gerald R; Hinshaw, Stephen M; Wong, Kwok-Kin; Gray, Nathanael S

Journal of the American Chemical Society. 2026 Jan 14; 148(1):1153-1163

Phase 1b Study of Dazostinag Plus Pembrolizumab After Hypofractionated Radiotherapy in Patients With Select Advanced Solid Tumors

Cooper, Benjamin T; Iams, Wade T; Page, David B; Yuan, Yuan; Gerber, Naamit K; Luke, Jason J; Gibbs, John P; Gregory, Richard C; Wong, Kwok-Kin; Deng, Jiehui; Perera, Samanthi A; Ding, Kai; Roberts, Emily R; Berger, Allison; Christensen, Camilla L; Tong, Erica Xin; Maldonado López, Angel E; Appleman, Vicky A; Leonard, E Jane; Parent, Alexander; Huang, Yu-Chung; Bay, Camden; Li, Cong; Lineberry, Neil; Raizer, Jeffrey; Olson, Daniel J; Chmura, Steven J

Cancer research communications. 2025 Dec 01; 5(12):2249-2263

Tumor Cell Plasticity in Cancer: Signaling Pathways and Pharmaceutical Interventions

Sun, Shangwei; Sun, Yunwei; Lan, Ling; Luan, Siyuan; Zhou, Jin; Deng, Jiehui; Yuan, Yong; Wu, Zhong

MedComm. 2025 Dec; 6(12):e70541

TNG260 is a Small-Molecule CoREST Inhibitor that Sensitizes STK11-Mutant Tumors to Anti-PD-1 Immunotherapy

Ahronian, Leanne G; Sahu, Soumyadip; Zhang, Minjie; Patel, Ayushi S; Geng, Ke; Bhattacharya, Reshmee; Falchook, Gerald S; Goldman, Jonathan W; Spira, Alexander I; Punekar, Salman R; Spigel, David R; Wang, Judy S; Skoulidis, Ferdinandos; Stephens, Janaye; Meynardie, Mary; Powell, Jaylen M; Lopez, Alfonso; Ranieri, Michela; Ploszaj, Magdalena A; Tan, Yi Jer; Lee, Yeuan Ting; Yu, Yi; Deng, Jiehui; Chen, Ting; McCarren, Patrick; Tsai, Alice; Hussain, Suleman S; Doyon, Brian; Amemiya, Kenjie; Ermolieff, Jacques; Shahagadkar, Preksha; Das, Nikitha M; Flynn, Lauren R; Shields, Julie A; Danielczyk, Laney; McMillan, Brian J; Mignault, Andre; Meier, Samuel R; Wu, Hsin-Jung; Guerin, David J; Whittington, Douglas A; Min, Chengyin; Sienczylo, Iga; Maxwell, John P; DiBenedetto, Heather J; Watanabe, Hideo; Haines, Brian B; Huang, Alan; Crystal, Adam; Andersen, Jannik N; Wu, Xinyuan; Wong, Kwok-Kin

Cancer research. 2025 Oct 15; 85(20):3966-3982

Deep mutational scanning reveals EGFR mutations conferring resistance to the 4th-generation EGFR tyrosine kinase inhibitor BLU-945

Wang, Yueyang; Hao, Yuan; Ranieri, Michela; Abramyan, Tigran M; Tsidilkovski, Lev; Hollenberg, Michelle; Lopez, Alfonso; Moore, Xavier T R; Sherman, Fiona; Deng, Jiehui; Saribekyan, Hayk; Papoian, Garegin; Wong, Kwok-Kin; Shum, Elaine; Poirier, John T

NPJ precision oncology. 2025 Aug 20; 9(1):294

A Phase 1/2 multicenter trial of DKN-01 as monotherapy or in combination with docetaxel for the treatment of metastatic castration-resistant prostate cancer (mCRPC)

Wise, David R; Pachynski, Russell K; Denmeade, Samuel R; Aggarwal, Rahul R; Deng, Jiehui; Febles, Victor Adorno; Balar, Arjun V; Economides, Minas P; Loomis, Cynthia; Selvaraj, Shanmugapriya; Haas, Michael; Kagey, Michael H; Newman, Walter; Baum, Jason; Troxel, Andrea B; Griglun, Sarah; Leis, Dayna; Yang, Nina; Aranchiy, Viktoriya; Machado, Sabrina; Waalkes, Erika; Gargano, Gabrielle; Soamchand, Nadia; Puranik, Amrutesh; Chattopadhyay, Pratip; Fedal, Ezeddin; Deng, Fang-Ming; Ren, Qinghu; Chiriboga, Luis; Melamed, Jonathan; Sirard, Cynthia A; Wong, Kwok-Kin

Prostate cancer & prostatic diseases. 2025 Jun; 28(2):363-369

Characterization of tumour heterogeneity through segmentation-free representation learning on multiplexed imaging data

Tan, Jimin; Le, Hortense; Deng, Jiehui; Liu, Yingzhuo; Hao, Yuan; Hollenberg, Michelle; Liu, Wenke; Wang, Joshua M; Xia, Bo; Ramaswami, Sitharam; Mezzano, Valeria; Loomis, Cynthia; Murrell, Nina; Moreira, Andre L; Cho, Kyunghyun; Pass, Harvey I; Wong, Kwok-Kin; Ban, Yi; Neel, Benjamin G; Tsirigos, Aristotelis; Fenyö, David

Nature biomedical engineering. 2025 Mar; 9(3):405-419

Characterization of tumor heterogeneity through segmentation-free representation learning

Tan, Jimin; Le, Hortense; Deng, Jiehui; Liu, Yingzhuo; Hao, Yuan; Hollenberg, Michelle; Liu, Wenke; Wang, Joshua M; Xia, Bo; Ramaswami, Sitharam; Mezzano, Valeria; Loomis, Cynthia; Murrell, Nina; Moreira, Andre L; Cho, Kyunghyun; Pass, Harvey; Wong, Kwok-Kin; Ban, Yi; Neel, Benjamin G; Tsirigos, Aristotelis; Fenyö, David

bioRxiv.org : the preprint server for biology. 2024 Sep 06;

See All Publications (55)