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Jonas Schluter

Jonas Schluter, PhD

Institute for Computational Medicine

Assistant Professor, Department of Microbiology

Keywords
gut microbiome, massive clinical data sets and the hospitalome, microbial ecology and warfare, evolutionary theory, quorum sensing, machine-learning and Bayesian time series analysis, microbiota, cancer, immunity, immunology
Summary

We seek to leverage the human microbiota as a therapeutic target of the future. We approach this ambitious goal from two opposing directions: on the one end, we utilize massive datasets to detect temporal associations between the gut microbiota and the body, with particular emphasis on immune homeostasis; on the other end, we are developing fundamental theory of host-microbiota evolution and ecology. Theory and large-scale data analysis inform our microbiota community experiments, focusing on anaerobic cultivation techniques, that ultimately lead to interventional trials of microbiota-targeted therapies. Specifically, we are leveraging the arsenal of microbial warfare to control complex microbial ecosystems.

Phone

212-263-6973

Academic office

435 East 30th Street, Science Building

8th floor, SB815

New York City, NY 10016

Lab Website
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PhD from University of Oxford

Memorial Sloan Kettering Cancer Center, Xavier Lab / Computational Biology Group

Coyte, Katharine Z; Schluter, Jonas; Foster, Kevin R

Science. 2015 Nov 06; 350(6261):663-6

Schluter, Jonas; Foster, Kevin R

PLoS biology. 2012 Apr; 10(11):e1001424

Foster, Kevin R; Schluter, Jonas; Coyte, Katharine Z; Rakoff-Nahoum, Seth

Nature. 2017 08 02; 548(7665):43-51

Taur, Ying; Coyte, Katharine; Schluter, Jonas; Robilotti, Elizabeth; Figueroa, Cesar; Gjonbalaj, Mergim; Littmann, Eric R; Ling, Lilan; Miller, Liza; Gyaltshen, Yangtsho; Fontana, Emily; Morjaria, Sejal; Gyurkocza, Boglarka; Perales, Miguel-Angel; Castro-Malaspina, Hugo; Tamari, Roni; Ponce, Doris; Koehne, Guenther; Barker, Juliet; Jakubowski, Ann; Papadopoulos, Esperanza; Dahi, Parastoo; Sauter, Craig; Shaffer, Brian; Young, James W; Peled, Jonathan; Meagher, Richard C; Jenq, Robert R; van den Brink, Marcel R M; Giralt, Sergio A; Pamer, Eric G; Xavier, Joao B

Science translational medicine. 2018 09 26; 10(460):

Morjaria, Sejal; Schluter, Jonas; Taylor, Bradford P; Littmann, Eric R; Carter, Rebecca A; Fontana, Emily; Peled, Jonathan U; van den Brink, Marcel R M; Xavier, Joao B; Taur, Ying

Infection & immunity. 2019 09; 87(9):

McLoughlin, Kirstie; Schluter, Jonas; Rakoff-Nahoum, Seth; Smith, Adrian L; Foster, Kevin R

Cell host & microbe. 2016 Apr 13; 19(4):550-9

Schulfer, Anjelique F; Schluter, Jonas; Zhang, Yilong; Brown, Quincy; Pathmasiri, Wimal; McRitchie, Susan; Sumner, Susan; Li, Huilin; Xavier, Joao B; Blaser, Martin J

ISME journal. 2019 May; 13(5):1280-1292

Markey, Kate A; Schluter, Jonas; Gomes, Antonio Lc; Littmann, Eric; Pickard, Amanda; Taylor, Bradford P; Giardina, Paul A; Weber, Daniela; Dai, Anqi; Docampo, Melissa; Armijo, Gabriel K; Slingerland, Ann; Slingerland, John; Nichols, Katherine B; Brereton, Daniel G; Clurman, Annelie; Ramos, Ruben J; Rao, Arka; Bush, Amy T; Bohannon, Lauren; Covington, Megan; Lew, Meagan V; Rizzieri, David A; Chao, Nelson J; Maloy, Molly; Cho, Christina; Politikos, Ioannis; Giralt, Sergio; Taur, Ying; Pamer, Eric; Holler, Ernst; Perales, Miguel-Angel; Ponce, Doris M; Devlin, Sean M; Xavier, Joao; Sung, Anthony; Peled, Jonathan U; Cross, Justin R; van den Brink, Marcel Rm

Blood. 2020 Jul 02; 136(1):130-136