Jordan Weiss

Jordan Weiss, PhD

Assistant Professor, Department of Medicine

Keywords
aging, causal inference, dementia, electronic health records, machine learning, multistate modeling, target trial emulation
Summary
I am an assistant professor in the Division of Precision Medicine and Optimal Aging Institute. I do research to understand why some people stay healthy as they age while others do not.    My work aims to solve for the gap between healthspan (the length of time an individual maintains good health) and lifespan (the total length of time an individual lives) by identifying how and for whom key exposures over the life course shape trajectories of health and well-being. I design observational studies that leverage causal inference and AI-based methods, combined with large cohort studies and healthcare records, to emulate hypothetical randomized trials. These studies inform individualized prediction and treatment strategies to optimize health and aging processes.

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Positions

Assistant Professor, Department of Medicine at NYU Grossman School of Medicine

Graduate Education

PhD from University of Pennsylvania

Postdoctoral Training

University of California, Berkeley, Department of Demography

Polypharmacy and its association with dementia, Parkinson's disease, and mortality risk in UK adults: a multistate modeling approach

Weiss, Jordan; Beydoun, May A; Georgescu, Michael F; Maldonado, Ana I; Beydoun, Hind A; Noren Hooten, Nicole; Tsai, Jack; Song, Minkyo; Nieva, Allen; Evans, Michele K; Zonderman, Alan B

GeroScience. 2025 Mar 13;

Mediating and moderating effects of plasma proteomic biomarkers on the association between poor oral health problems and brain white matter microstructural integrity: the UK Biobank study

Beydoun, May A; Beydoun, Hind A; Hu, Yi-Han; Li, Zhiguang; Georgescu, Michael F; Noren Hooten, Nicole; Bouhrara, Mustapha; Weiss, Jordan; Launer, Lenore J; Evans, Michele K; Zonderman, Alan B

Molecular psychiatry. 2025 Feb; 30(2):388-401

Cardiovascular disease, bone fracture, and all-cause mortality risks among postmenopausal women by arthritis and veteran status: A multistate Markov transition analysis

Beydoun, Hind A; Beydoun, May A; Weiss, Jordan; Brunner, Robert; Mishra, Nishant K; Ding, Ming; Wactawski-Wende, Jean; Gradidge, Philippe Jean-Luc; Liu, Simin; Tsai, Jack

GeroScience. 2025 Jan 29;

Lifetime risk and projected burden of dementia

Fang, Michael; Hu, Jiaqi; Weiss, Jordan; Knopman, David S; Albert, Marilyn; Windham, B Gwen; Walker, Keenan A; Sharrett, A Richey; Gottesman, Rebecca F; Lutsey, Pamela L; Mosley, Thomas; Selvin, Elizabeth; Coresh, Josef

Nature medicine. 2025 Jan 13;

Pathways explaining racial/ethnic and socio-economic disparities in brain white matter integrity outcomes in the UK Biobank study

Weiss, Jordan; Beydoun, May A; Beydoun, Hind A; Georgescu, Michael F; Hu, Yi-Han; Noren Hooten, Nicole; Banerjee, Sri; Launer, Lenore J; Evans, Michele K; Zonderman, Alan B

SSM - Population health. 2024 Jun; 26:101655

Depressive symptoms and antidepressant use in relation to white blood cell count among postmenopausal women from the Women's Health Initiative

Beydoun, Hind A; Beydoun, May A; Wassertheil-Smoller, Sylvia; Saquib, Nazmus; Manson, JoAnn E; Snetselaar, Linda; Weiss, Jordan; Zonderman, Alan B; Brunner, Robert

Translational psychiatry. 2024 Mar 21; 14(1):157

Helicobacter pylori, persistent infection burden and structural brain imaging markers

Beydoun, May A; Beydoun, Hind A; Hu, Yi-Han; El-Hajj, Ziad W; Georgescu, Michael F; Noren Hooten, Nicole; Li, Zhiguang; Weiss, Jordan; Lyall, Donald M; Waldstein, Shari R; Hedges, Dawson W; Gale, Shawn D; Launer, Lenore J; Evans, Michele K; Zonderman, Alan B

Brain communications. 2024; 6(2):fcae088

Hospital-treated prevalent infections, the plasma proteome and incident dementia among UK older adults

Beydoun, May A; Beydoun, Hind A; Noren Hooten, Nicole; Meirelles, Osorio; Li, Zhiguang; El-Hajj, Ziad W; Weiss, Jordan; Maino Vieytes, Christian A; Launer, Lenore J; Evans, Michele K; Zonderman, Alan B

iScience. 2023 Dec 15; 26(12):108526

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