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Karim-Jean Armache, PhD

Associate Professor, Department of Biochemistry and Molecular Pharmacology

Keywords
biophysics, cancer, developmental genetics, genome integrity, metabolism, stem cell biology

Phone

212-263-0585

Academic office

540 First Avenue, Skirball Institute

3, 17

New York, NY 10016

Lab Website
Armache Lab
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Positions

Associate Professor, Department of Biochemistry and Molecular Pharmacology at NYU Grossman School of Medicine

Graduate Education

PhD from Ludwig Maximillians University Munich

Giant variations in giant virus genome packaging

Talbert, Paul B; Henikoff, Steven; Armache, Karim-Jean

Trends in biochemical sciences. 2023 Dec; 48(12):1071-1082

Catalytic and non-catalytic mechanisms of histone H4 lysine 20 methyltransferase SUV420H1

Abini-Agbomson, Stephen; Gretarsson, Kristjan; Shih, Rochelle M; Hsieh, Laura; Lou, Tracy; De Ioannes, Pablo; Vasilyev, Nikita; Lee, Rachel; Wang, Miao; Simon, Matthew D; Armache, Jean-Paul; Nudler, Evgeny; Narlikar, Geeta; Liu, Shixin; Lu, Chao; Armache, Karim-Jean

Molecular cell. 2023 Aug 17; 83(16):2872-2883.e7

Structural basis of histone H2A lysine 119 deubiquitination by Polycomb repressive deubiquitinase BAP1/ASXL1

Thomas, Jonathan F; Valencia-Sánchez, Marco Igor; Tamburri, Simone; Gloor, Susan L; Rustichelli, Samantha; Godínez-López, Victoria; De Ioannes, Pablo; Lee, Rachel; Abini-Agbomson, Stephen; Gretarsson, Kristjan; Burg, Jonathan M; Hickman, Allison R; Sun, Lu; Gopinath, Saarang; Taylor, Hailey F; Sun, Zu-Wen; Ezell, Ryan J; Vaidya, Anup; Meiners, Matthew J; Cheek, Marcus A; Rice, William J; Svetlov, Vladimir; Nudler, Evgeny; Lu, Chao; Keogh, Michael-Christopher; Pasini, Diego; Armache, Karim-Jean

Science advances. 2023 Aug 09; 9(32):eadg9832

Intrinsic mesoscale properties of a Polycomb protein underpin heterochromatin fidelity

Lee, Sujin; Abini-Agbomson, Stephen; Perry, Daniela S; Goodman, Allen; Rao, Beiduo; Huang, Manning Y; Diedrich, Jolene K; Moresco, James J; Yates, John R; Armache, Karim-Jean; Madhani, Hiten D

Nature structural & molecular biology. 2023 Jul; 30(7):891-901

A giant virus genome is densely packaged by stable nucleosomes within virions

Bryson, Terri D; De Ioannes, Pablo; Valencia-Sánchez, Marco Igor; Henikoff, Jorja G; Talbert, Paul B; Lee, Rachel; La Scola, Bernard; Armache, Karim-Jean; Henikoff, Steven

Molecular cell. 2022 Dec 01; 82(23):4458-4470.e5

Viral histones: pickpocket's prize or primordial progenitor?

Talbert, Paul B; Armache, Karim-Jean; Henikoff, Steven

Epigenetics & chromatin. 2022 May 28; 15(1):21

The structure of a virus-encoded nucleosome

Valencia-Sánchez, Marco Igor; Abini-Agbomson, Stephen; Wang, Miao; Lee, Rachel; Vasilyev, Nikita; Zhang, Jenny; De Ioannes, Pablo; La Scola, Bernard; Talbert, Paul; Henikoff, Steve; Nudler, Evgeny; Erives, Albert; Armache, Karim-Jean

Nature structural & molecular biology. 2021 May; 28(5):413-417

Structures of monomeric and dimeric PRC2:EZH1 reveal flexible modules involved in chromatin compaction

Grau, Daniel; Zhang, Yixiao; Lee, Chul-Hwan; Valencia-Sánchez, Marco; Zhang, Jenny; Wang, Miao; Holder, Marlene; Svetlov, Vladimir; Tan, Dongyan; Nudler, Evgeny; Reinberg, Danny; Walz, Thomas; Armache, Karim-Jean

Nature communications. 2021 Jan 29; 12(1):714

See All Publications (25)

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