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Karim-Jean Armache, PhD

Associate Professor, Department of Biochemistry and Molecular Pharmacology

Keywords
biophysics, cancer, developmental genetics, genome integrity, metabolism, stem cell biology

Phone

212-263-0585

Academic office

540 First Avenue, Skirball Institute

3, 17

New York, NY 10016

Lab Website
Armache Lab
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Positions

Associate Professor, Department of Biochemistry and Molecular Pharmacology at NYU Grossman School of Medicine

Graduate Education

PhD from Ludwig Maximillians University Munich

The structure of a virus-encoded nucleosome

Valencia-Sánchez, Marco Igor; Abini-Agbomson, Stephen; Wang, Miao; Lee, Rachel; Vasilyev, Nikita; Zhang, Jenny; De Ioannes, Pablo; La Scola, Bernard; Talbert, Paul; Henikoff, Steve; Nudler, Evgeny; Erives, Albert; Armache, Karim-Jean

Nature structural & molecular biology. 2021 May; 28(5):413-417

Structures of monomeric and dimeric PRC2:EZH1 reveal flexible modules involved in chromatin compaction

Grau, Daniel; Zhang, Yixiao; Lee, Chul-Hwan; Valencia-Sánchez, Marco; Zhang, Jenny; Wang, Miao; Holder, Marlene; Svetlov, Vladimir; Tan, Dongyan; Nudler, Evgeny; Reinberg, Danny; Walz, Thomas; Armache, Karim-Jean

Nature communications. 2021 Jan 29; 12(1):714

Regulation of the Dot1 histone H3K79 methyltransferase by histone H4K16 acetylation

Valencia-Sánchez, Marco Igor; De Ioannes, Pablo; Wang, Miao; Truong, David M; Lee, Rachel; Armache, Jean-Paul; Boeke, Jef D; Armache, Karim-Jean

Science. 2021 01 22; 371(6527):

Histone H3.3 phosphorylation amplifies stimulation-induced transcription

Armache, Anja; Yang, Shuang; Martínez de Paz, Alexia; Robbins, Lexi E; Durmaz, Ceyda; Cheong, Jin Q; Ravishankar, Arjun; Daman, Andrew W; Ahimovic, Dughan J; Klevorn, Thaís; Yue, Yuan; Arslan, Tanja; Lin, Shu; Panchenko, Tanya; Hrit, Joel; Wang, Miao; Thudium, Samuel; Garcia, Benjamin A; Korb, Erica; Armache, Karim-Jean; Rothbart, Scott B; Hake, Sandra B; Allis, C David; Li, Haitao; Josefowicz, Steven Z

Nature. 2020 Jul; 583(7818):852-857

RNA-DNA strand exchange by the Drosophila Polycomb complex PRC2

Alecki, Célia; Chiwara, Victoria; Sanz, Lionel A; Grau, Daniel; Arias Pérez, Osvaldo; Boulier, Elodie L; Armache, Karim-Jean; Chédin, Frédéric; Francis, Nicole J

Nature communications. 2020 Apr 14; 11(1):1781

Structure and function of the Orc1 BAH-nucleosome complex

De Ioannes, Pablo; Leon, Victor A; Kuang, Zheng; Wang, Miao; Boeke, Jef D; Hochwagen, Andreas; Armache, Karim-Jean

Nature communications. 2019 Jul 01; 10(1):2894

Structural Basis of Dot1L Stimulation by Histone H2B Lysine 120 Ubiquitination

Valencia-Sánchez, Marco Igor; De Ioannes, Pablo; Wang, Miao; Vasilyev, Nikita; Chen, Ruoyu; Nudler, Evgeny; Armache, Jean-Paul; Armache, Karim-Jean

Molecular cell. 2019 Jun 06; 74(5):1010-1019.e6

Distinct Stimulatory Mechanisms Regulate the Catalytic Activity of Polycomb Repressive Complex 2

Lee, Chul-Hwan; Holder, Marlene; Grau, Daniel; Saldaña-Meyer, Ricardo; Yu, Jia-Ray; Ganai, Rais Ahmad; Zhang, Jenny; Wang, Miao; LeRoy, Gary; Dobenecker, Marc-Werner; Reinberg, Danny; Armache, Karim-Jean

Molecular cell. 2018 05 03; 70(3):435-448.e5

See All Publications (19)

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