Ken H. Cadwell

Ken H. Cadwell, PhD

Skirball Institute

Associate Professor, Department of Microbiology

Keywords
cancer, immunology, metabolism, microbiology, microbiome, understanding how infectious agents and the microbiome regulate susceptibility to inflammatory disease
Summary

The Cadwell Lab investigates how the immune system is controlled during infectious and inflammatory diseases. The immune system is tasked with defending against life-threatening infectious agents, but at the same time must avoid unnecessary reactions against beneficial microbes that are part of the microbiome. Such unwanted immune responses are implicated in a variety of chronic diseases including inflammatory bowel disease and cancer. A key research goal is to uncover the cell biological processes that control the immune response when confronted with the diverse infectious agents found in the environment. Ongoing projects include: (1) Identifying gene-microbe interactions that contribute to inflammatory bowel disease, (2) elucidating the role of the cellular process of autophagy in host-pathogen interactions, and (3) examining the viral component of the microbiome, also known as the virome.

Phone

212-263-8891

Academic office

Alexandria Ctr, West Tower, 430 East 29th Street

Room 409

New York, NY 10016

Lab Website
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Associate Professor, Department of Microbiology

PhD from University of California at Berkeley

Fellowship, Washington Univesity School of Medicine, Pathology and Immunology

Martin, Patricia K; Marchiando, Amanda; Xu, Ruliang; Rudensky, Eugene; Yeung, Frank; Schuster, Samantha L; Kernbauer, Elisabeth; Cadwell, Ken

Nature microbiology. 2018 Oct 12; 3(10):1131-1141

Axelrad, Jordan E; Joelson, Andrew; Green, Peter H R; Lawlor, Garrett; Lichtiger, Simon; Cadwell, Ken; Lebwohl, Benjamin

American journal of gastroenterology. 2018 Oct 04; 113(10):1530-1539

Wong, Serre-Yu; Cadwell, Ken

PLoS pathogens. 2018 Sep 20; 14(9):e1007215-e1007215

Neil, Jessica A; Cadwell, Ken

Journal of immunology (1950). 2018 Sep 15; 201(6):1615-1624

Wong, Serre-Yu; Coffre, Maryaline; Ramanan, Deepshika; Hines, Marcus J; Gomez, Luis E; Peters, Lauren A; Schadt, Eric E; Koralov, Sergei B; Cadwell, Ken

Journal of immunology (1950). 2018 Sep 01; 201(5):1442-1451

Loke, P'ng; Cadwell, Ken

Immunity. 2018 Jul 17; 49(1):16-18

Axelrad, Jordan E; Lebwohl, Benjamin; Cuaresma, Edward; Cadwell, Ken; Green, Peter H R; Freedberg, Daniel E

Gut pathogens. 2018 Jul 09; 10:28-28

A Gut Parasite Helps Fight Inflammatory Bowel Disease

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