Research Professor, Department of Microbiology
The Cadwell Lab investigates how the immune system is controlled during infectious and inflammatory diseases. The immune system is tasked with defending against life-threatening infectious agents, but at the same time must avoid unnecessary reactions against beneficial microbes that are part of the microbiome. Such unwanted immune responses are implicated in a variety of chronic diseases including inflammatory bowel disease and cancer. A key research goal is to uncover the cell biological processes that control the immune response when confronted with the diverse infectious agents found in the environment. Ongoing projects include: (1) Identifying gene-microbe interactions that contribute to inflammatory bowel disease, (2) elucidating the role of the cellular process of autophagy in host-pathogen interactions, and (3) examining the viral component of the microbiome, also known as the virome.
Research Professor, Department of Microbiology at NYU Grossman School of Medicine
PhD from University of California at Berkeley
Fellowship, Washington Univesity School of Medicine, Pathology and Immunology
Journal of clinical investigation. 2024 Jan 09; 134(4):
Scientific reports. 2024 Jan 02; 14(1):186
Science advances. 2023 Dec 22; 9(51):eadh8310
Gut microbes. 2023 Dec; 15(2):2249960
Arthritis & rheumatology. 2023 Nov 22;
Annual review of virology. 2023 Sep 29; 10(1):477-502
Cell host & microbe. 2023 Sep 13; 31(9):1450-1468.e8
PLoS pathogens. 2023 Sep; 19(9):e1011647