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Konstantin Ichtchenko

Konstantin Ichtchenko

Assistant Professor, Department of Biochemistry and Molecular Pharmacology

Positions

Assistant Professor, Department of Biochemistry and Molecular Pharmacology at NYU Grossman School of Medicine

Course Director

Phone

212-263-2301

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Academic office

455 First Avenue, Public Health Bldg.

8, 874

New York, NY 10016

Yeast Display Enables Identification of Covalent Single-Domain Antibodies against Botulinum Neurotoxin Light Chain A

Alcala-Torano, Rafael; Islam, Mariha; Cika, Jaclyn; Lam, Kwok Ho; Jin, Rongsheng; Ichtchenko, Konstantin; Shoemaker, Charles B; Van Deventer, James A

ACS chemical biology. 2022 Dec 16; 17(12):3435-3449

Probing the structure and function of the protease domain of botulinum neurotoxins using single-domain antibodies

Lam, Kwok-Ho; Tremblay, Jacqueline M; Perry, Kay; Ichtchenko, Konstantin; Shoemaker, Charles B; Jin, Rongsheng

PLoS pathogens. 2022 Jan 06; 18(1):e1010169

Activity-dependent somatodendritic dopamine release in the substantia nigra autoinhibits the releasing neuron

Hikima, Takuya; Lee, Christian R; Witkovsky, Paul; Chesler, Julia; Ichtchenko, Konstantin; Rice, Margaret E

Cell reports. 2021 Apr 06; 35(1):108951

Neuronal delivery of antibodies has therapeutic effects in animal models of botulism

McNutt, Patrick M; Vazquez-Cintron, Edwin J; Tenezaca, Luis; Ondeck, Celinia A; Kelly, Kyle E; Mangkhalakhili, Mark; Machamer, James B; Angeles, Christopher A; Glotfelty, Elliot J; Cika, Jaclyn; Benjumea, Cesar H; Whitfield, Justin T; Band, Philip A; Shoemaker, Charles B; Ichtchenko, Konstantin

Science translational medicine. 2021 Jan 06; 13(575):

Camelid VHH Antibodies that Neutralize Botulinum Neurotoxin Serotype E Intoxication or Protease Function

Tremblay, Jacqueline M; Vazquez-Cintron, Edwin; Lam, Kwok-Ho; Mukherjee, Jean; Bedenice, Daniela; Ondeck, Celinia A; Conroy, Matthieu T; Bodt, Skylar M L; Winner, Brittany M; Webb, Robert P; Ichtchenko, Konstantin; Jin, Rongsheng; McNutt, Patrick M; Shoemaker, Charles B

Toxins. 2020 Sep 24; 12(10):

Engineering Botulinum Neurotoxin C1 as a Molecular Vehicle for Intra-Neuronal Drug Delivery

Vazquez-Cintron, Edwin J; Beske, Phillip H; Tenezaca, Luis; Tran, Bao Q; Oyler, Jonathan M; Glotfelty, Elliot J; Angeles, Christopher A; Syngkon, Aurelia; Mukherjee, Jean; Kalb, Suzanne R; Band, Philip A; McNutt, Patrick M; Shoemaker, Charles B; Ichtchenko, Konstantin

Scientific reports. 2017 02 21; 7:42923

Pre-Clinical Study of a Novel Recombinant Botulinum Neurotoxin Derivative Engineered for Improved Safety

Vazquez-Cintron, Edwin; Tenezaca, Luis; Angeles, Christopher; Syngkon, Aurelia; Liublinska, Victoria; Ichtchenko, Konstantin; Band, Philip

Scientific reports. 2016 08 03; 6:30429

Recombinant derivatives of botulinum neurotoxins: should derivatives with light chain inactivating mutations retain biological activity?

Band, Philip; Vazquez-Cintron, Edwin; Beske, Philip; Angeles, Christopher; Syngkon, Aurelia; McNutt, Patrick; Ichtchenko, Konstantin

Toxicon. 2015 Jan; 93(Suppl):S5-S6

See All Publications (22)