Lauren C. Shuffrey

Lauren C. Shuffrey, PhD

Assistant Professor, Department of Child and Adolescent Psychiatry

Summary

The prenatal environment significantly influences physical and mental health across the lifespan, yet the underlying mechanisms remain unclear. My research program investigates pregnancy as a critical developmental window for both maternal mental health and infant brain-behavioral outcomes. At the RESILIENT Lab, our projects primarily explore the impact of prenatal maternal metabolic disorders, stress, early-life trauma, and substance exposure on these outcomes, from birth through early childhood. We employ a diverse range of methodologies, including bioassays, physiological monitoring, behavioral assessments, eye tracking, and electroencephalography (EEG), to address our research questions. Our overarching goal is to uncover mechanisms, identify objective markers, and pinpoint modifiable factors that promote resiliency, ultimately supporting families from pregnancy through early childhood.

Academic office

1 Park Ave

7th Floor

New York, NY 10016

Lab Website
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Lead, Research Analytic Strategy, Department of Child & Adolescent Psychiatry

Fellowship, Columbia University Medical Center, National Institute of Mental Health (NIMH) Translational Research in Child Psychiatric Disorders Training Program (Institutional T32)

Yang, Huiyu; Liu, Ran; Simon, Katrina R; Gimenez, Lissete A; Bowers, Maureen E; Pini, Nicolò; Leach, Stephanie C; Salas, Leilani; Shuffrey, Lauren C; Fifer, William P; Herbstman, Julie; Fox, Nathan A; Margolis, Amy E

Developmental cognitive neuroscience. 2026 Apr 20; 79:101727

Xu, Xiaoye; Shuffrey, Lauren C; Bastain, Theresa M; Liu, Chang; Wright, Rosalind J; Bosquet Enlow, Michelle; Hernandez, Alexis; Ganiban, Jody; Nozadi, Sara S; Margolis, Amy E; Elliott, Amy J; Morales, Santiago

Development & psychopathology. 2026 Feb 16; 1-11

Hu, Yunzhe; Collazo Vargas, Julianna I; Hockett, Christine; Ziegler, Katherine; Brito, Natalie H; Akbaryan, Anahid; Costello, Lauren A; Elliott, Amy J; Fifer, William P; Morales, Santiago; Shuffrey, Lauren C

Development & psychopathology. 2026 Feb 06; 1-12

Sania, Ayesha; Rao, Shreya; Pini, Nicolò; Potter, Mandy; Rayport, Yael; Eisler, Liana; Brink, Lucy; Angal, Jyoti; Myers, Michael M; Odendaal, Hein; Elliott, Amy J; Fifer, William P; Shuffrey, Lauren C

PLoS one. 2026 Apr; 21(4):e0345406

Banker, Sarah M; Shapiro-Thompson, Rosa; Sinsel, Sarah; Ghassabian, Akhgar; Douglas, Christian; Nelson, Morgan E; Peterson, Lisa A; Thyagarajan, Bharat; Morales, Santiago; Hockett, Christine W; Elliott, Amy J; Giamberardino, Stephanie N; Shuffrey, Lauren C

Frontiers in immunology. 2026 Apr; 17:1803430

Akbaryan, Anahid; Churchill, Marie L; McGrath, Monica; Alshawabkeh, Akram; Enlow, Michelle Bosquet; Brennan, Patricia A; Collazo Vargas, Julianna; Costello, Lauren A; D'Sa, Viren; Dunlop, Anne; Elliott, Amy J; Firestein, Morgan; Ghassabian, Akhgar; Hofheimer, Julie A; Koinis-Mitchell, Daphne; Margolis, Amy; Morales, Santiago; Morello-Frosch, Rachel; Nozadi, Sara S; O'Connor, Thomas G; Schantz, Susan L; Woodruff, Tracey; Wright, Rosalind J; Shuffrey, Lauren C; ,

JAMA network open. 2025 Sep 02; 8(9):e2530346

Volk, Heather E; Fortes, Diogo; Musci, Rashelle; Kim, Amanda; Bastain, Theresa M; Camargo, Carlos A; Croen, Lisa A; Dabelea, Dana; Duarte, Cristiane S; Dunlop, Anne L; Gachigi, Kennedy; Ghassabian, Akhgar; Hertz-Picciotto, Irva; Huddleston, Kathi C; Joseph, Robert M; Keating, Daniel; Kelly, Rachel S; Kim, Young Shin; Landa, Rebecca J; Leve, Leslie D; Lyall, Kristen; Northrup, Jessie B; O'Connor, Thomas; Ozonoff, Sally; Ross, Anna; Schmidt, Rebecca J; Schweitzer, Julie B; Shuffrey, Lauren C; Shuster, Coral; Vance, Emily; Weiss, Scott T; Wilkening, Greta; Wright, Robert O

Journal of autism & developmental disorders. 2025 Jan 06;

Shuffrey, Lauren C; Rennie, Brandon; Li, Xiuhong; Galai, Noya; Pini, Nicolò; Akbaryan, Anahid; Alshawabkeh, Akram; Aschner, Judy; Vargas, Julianna Collazo; Costello, Lauren; D'Sa, Viren; Deoni, Sean; Dunlop, Anne; Elliott, Amy J; Fifer, William P; Hash, Jonica; Koinis-Mitchell, Daphne; Lai, Jin-Shei; Leventhal, Bennett L; Lewis, Johnnye; Lucchini, Maristella; McArthur, Kristen L; Morales, Santiago; Nozadi, Sara S; O'Connor, Thomas G; O'Shea, T Michael; Page, Grier P; Propper, Cathi; Sania, Ayesha; Shuster, Coral; Zimmerman, Emily; Margolis, Amy E; ,

Pediatric research. 2025 Jan; 97(1):411-421