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Liam J. Holt

Liam J. Holt, PhD

Institute for Systems Genetics

Assistant Professor, Department of Biochemistry and Molecular Pharmacology

Keywords
Synthetic Biology, Systems Biology, Cancer, Neurodegeneration, Cell biology, Mechanobiology, Cell division, Signalling
Summary

We study fundamental biology (information processing, mechanobiology, stem cells, evolution) apply our knowledge to disease (cancer, neurodegeneration) and use synthetic biology to test our understanding and hack life.

Lab website: https://www.liamholtlab.org/

Phone

646-501-4597

Academic office

435 East 30th Street

9th Floor, Room 906

New York, NY 10016

Lab Website
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Assistant Professor, Department of Biochemistry and Molecular Pharmacology

PhD from University of California, San Francisco

Fellowship, University of California Berkeley, Holt lab

Delarue, M; Brittingham, G P; Pfeffer, S; Surovtsev, I V; Pinglay, S; Kennedy, K J; Schaffer, M; Gutierrez, J I; Sang, D; Poterewicz, G; Chung, J K; Plitzko, J M; Groves, J T; Jacobs-Wagner, C; Engel, B D; Holt, L J

Cell. 2018 Jul 12; 174(2):338-349.e20

Neurohr, Gabriel E; Terry, Rachel L; Lengefeld, Jette; Bonney, Megan; Brittingham, Gregory P; Moretto, Fabien; Miettinen, Teemu P; Vaites, Laura Pontano; Soares, Luis M; Paulo, Joao A; Harper, J Wade; Buratowski, Stephen; Manalis, Scott; van Werven, Folkert J; Holt, Liam J; Amon, Angelika

Cell. 2019 Feb 21; 176(5):1083-1097.e18

Boeke, Jef D; Church, George; Hessel, Andrew; Kelley, Nancy J; Arkin, Adam; Cai, Yizhi; Carlson, Rob; Chakravarti, Aravinda; Cornish, Virginia W; Holt, Liam; Isaacs, Farren J; Kuiken, Todd; Lajoie, Marc; Lessor, Tracy; Lunshof, Jeantine; Maurano, Matthew T; Mitchell, Leslie A; Rine, Jasper; Rosser, Susan; Sanjana, Neville E; Silver, Pamela A; Valle, David; Wang, Harris; Way, Jeffrey C; Yang, Luhan

Science. 2016 Jul 08; 353(6295):126-7

Delarue, Morgan; Poterewicz, Gregory; Hoxha, Ori; Choi, Jessica; Yoo, Wonjung; Kayser, Jona; Holt, Liam; Hallatschek, Oskar

Proceedings of the National Academy of Sciences of the United States of America (PNAS). 2017 12 19; 114(51):13465-13470

Holt, L J; Hallatschek, O; Delarue, M

Methods in cell biology. 2018 Sep; 147:215-231

Howard, Conor J; Hanson-Smith, Victor; Kennedy, Kristopher J; Miller, Chad J; Lou, Hua Jane; Johnson, Alexander D; Turk, Benjamin E; Holt, Liam J

eLife. 2014 Oct 13; 3:

Holt, Liam J; Tuch, Brian B; Villen, Judit; Johnson, Alexander D; Gygi, Steven P; Morgan, David O

Science. 2009 Sep 25; 325(5948):1682-6

Holt, Liam J; Krutchinsky, Andrew N; Morgan, David O

Nature. 2008 Jul 17; 454(7202):353-7