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Lung-Chi Chen

Lung-Chi Chen, PhD

Research Professor, Department of Medicine

nanoparticle toxicity and functional utilization, role of health disparity in air pollution-induced cardiopulmonary diseases, gene-environment interactions in environmentally induced diseases, effects of particulate air pollution in the pathogenesis of atherosclerosis, mechanisms of air pollution induced asthma, pollutant-induced alterations in biological response modifiers and associated membrane receptors, signal transduction pathways associated with oxidative stress

Dr. Chen is an internationally recognized expert on inhalation toxicology and has extensive experience in the measurement of cardiopulmonary effects of inhaled pollutants. He is also an expert in the generation and characterization of exposure atmospheres, and in the performance of toxicology studies using all routes of exposure, primarily those involving pulmonary exposure. He has served on a number of national and international committees and study sections in his areas of expertise. Dr. Chen is the author of over 120 research papers and book chapters dealing with the mechanisms underlying the adverse cardiopulmonary effects resulting from inhalation exposure to occupational and environmental air pollutants. His research approach is to systematically dissect the role that physico-chemical properties of these pollutants play in the exposure, uptake at sites of deposition in the respiratory tract and translocation to the heart, as well as in the development, progression, and resolution of cardiopulmonary diseases.



Academic office

57 Old Forge Rd.

Second Floor

Tuxedo, NY 10987

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These focus areas and their associated publications are derived from medical subject headings from PubMed.
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PhD from New York University

Iban-Arias, Ruth; Trageser, Kyle J; Yang, Eun-Jeong; Griggs, Elizabeth; Radu, Aurelian; Naughton, Sean; Al Rahim, Md; Tatsunori, Oguchi; Raval, Urdhva; Palmieri, Joshua; Huang, Zerlina; Chen, Lung-Chi; Pasinetti, Giulio Maria

Journal of Alzheimer's disease. 2023 Nov; 91(2):779-794

Li, Ran; Peng, Jing; Zhang, Wenhui; Wu, Yunlu; Hu, Renjie; Chen, Rucheng; Gu, Weijia; Zhang, Lu; Qin, Li; Zhong, Mianhua; Chen, Lung-Chi; Sun, Qinghua; Liu, Cuiqing

Ecotoxicology & environmental safety. 2022 May 24; 239:113680

Hernandez, Michelle; Vaughan, Joshua; Gordon, Terry; Lippmann, Morton; Gandy, Sam; Chen, Lung-Chi

Inhalation toxicology. 2022 May 09; 1-14

Park, Sung-Hyun; Lu, Yuting; Shao, Yongzhao; Prophete, Colette; Horton, Lori; Sisco, Maureen; Lee, Hyun-Wook; Kluz, Thomas; Sun, Hong; Costa, Max; Zelikoff, Judith; Chen, Lung-Chi; Gorr, Matthew W; Wold, Loren E; Cohen, Mitchell D

International journal of environmental research & public health. 2022 Jan 14; 19(2):

Gordon, Terry; Karey, Emma; Rebuli, Meghan E; Escobar, Yael; Jaspers, Ilona; Chi Chen, Lung

Annual review of pharmacology & toxicology. 2022 Jan 06; 62:301-322

Tang, Moon-Shong; Lee, Hyun-Wook; Weng, Mao-Wen; Wang, Hsiang-Tsui; Hu, Yu; Chen, Lung-Chi; Park, Sung-Hyun; Chan, Huei-Wei; Xu, Jiheng; Wu, Xue-Ru; Wang, He; Yang, Rui; Galdane, Karen; Jackson, Kathryn; Chu, Annie; Halzack, Elizabeth

Mutation research. Reviews in mutation research. 2022 Jan-Jun; 789:108409

Li, Lun; Liu, Yi; Chiu, Chin; Jin, Yang; Zhou, Weixun; Peng, Min; Chen, Lung-Chi; Sun, Qinghua; Gao, Jinming

Inflammation. 2021 Jun; 44(3):985-998

Park, Sung-Hyun; Lu, Yuting; Shao, Yongzhao; Prophete, Colette; Horton, Lori; Sisco, Maureen; Lee, Hyun-Wook; Kluz, Thomas; Sun, Hong; Costa, Max; Zelikoff, Judith; Chen, Lung-Chi; Cohen, Mitchell D

PLoS one. 2021 Aug; 16(10):e0257241