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Lung-Chi Chen

Lung-Chi Chen, PhD

Professor, Department of Environmental Medicine

nanoparticle toxicity and functional utilization, role of health disparity in air pollution-induced cardiopulmonary diseases, gene-environment interactions in environmentally induced diseases, effects of particulate air pollution in the pathogenesis of atherosclerosis, mechanisms of air pollution induced asthma, pollutant-induced alterations in biological response modifiers and associated membrane receptors, signal transduction pathways associated with oxidative stress

Dr. Chen is an internationally recognized expert on inhalation toxicology and has extensive experience in the measurement of cardiopulmonary effects of inhaled pollutants. He is also an expert in the generation and characterization of exposure atmospheres, and in the performance of toxicology studies using all routes of exposure, primarily those involving pulmonary exposure. He has served on a number of national and international committees and study sections in his areas of expertise. Dr. Chen is the author of over 120 research papers and book chapters dealing with the mechanisms underlying the adverse cardiopulmonary effects resulting from inhalation exposure to occupational and environmental air pollutants. His research approach is to systematically dissect the role that physico-chemical properties of these pollutants play in the exposure, uptake at sites of deposition in the respiratory tract and translocation to the heart, as well as in the development, progression, and resolution of cardiopulmonary diseases.



Academic office

57 Old Forge Rd.

Second Floor

Tuxedo, NY 10987

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These focus areas and their associated publications are derived from medical subject headings from PubMed.
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PhD from New York University

Li, Ran; Sun, Qing; Lam, Sin Man; Chen, Rucheng; Zhu, Junyao; Gu, Weijia; Zhang, Lu; Tian, He; Zhang, Kezhong; Chen, Lung-Chi; Sun, Qinghua; Shui, Guanghou; Liu, Cuiqing

Particle & fibre toxicology. 2020 04 22; 17(1):14

Tang, Moon-Shong; Wu, Xue-Ru; Lee, Hyun-Wook; Xia, Yong; Deng, Fang-Ming; Moreira, Andre L; Chen, Lung-Chi; Huang, William C; Lepor, Herbert

Proceedings of the National Academy of Sciences of the United States of America (PNAS). 2019 Oct 22; 116(43):21727-21731

Lieberman-Cribbin, Wil; Tuminello, Stephanie; Gillezeau, Christina; van Gerwen, Maaike; Brody, Rachel; Mulholland, David J; Horton, Lori; Sisco, Maureen; Prophete, Colette; Zelikoff, Judith; Lee, Hyun-Wook; Park, Sung-Hyun; Chen, Lung-Chi; Cohen, Mitchell D; Taioli, Emanuela

Journal of translational medicine. 2019 Oct 11; 17(1):342

Gong, Yixuan; Wang, Li; Yu, Haocheng; Alpert, Naomi; Cohen, Mitchell D; Prophete, Colette; Horton, Lori; Sisco, Maureen; Park, Sung-Hyun; Lee, Hyun-Wook; Zelikoff, Judith; Chen, Lung-Chi; Suarez-Farinas, Mayte; Donovan, Michael J; Aaronson, Stuart A; Galsky, Matthew; Zhu, Jun; Taioli, Emanuela; Oh, William K

Molecular cancer research. 2019 Aug; 17(8):1605-1612

Lim, Chris C; Kim, Ho; Vilcassim, M J Ruzmyn; Thurston, George D; Gordon, Terry; Chen, Lung-Chi; Lee, Kiyoung; Heimbinder, Michael; Kim, Sun-Young

Environment international. 2019 Jul 27; 131:105022

Vilcassim, M J Ruzmyn; Thurston, George D; Chen, Lung-Chi; Lim, Chris C; Gordon, Terry

American journal of respiratory & critical care medicine. 2019 Jun 15; 199(12):1570-1572

Vilcassim, M J Ruzmyn; Thurston, George D; Chen, Lung-Chi; Lim, Chris C; Saunders, Eric; Yao, Yixin; Gordon, Terry

Journal of travel medicine. 2019 Jun 11; 26(5):

Rao, Xiaoquan; Asico, Laureano D; Zanos, Panos; Mahabeleshwar, Ganapati H; Singh Gangwar, Roopesh; Xia, Chang; Duan, Lihua; Cisse, Yasmine-Marie; Rengasamy, Palanivel; Jose, Pedro A; Gould, Todd D; Nelson, Randy; Biswal, Shyam; Chen, Lung-Chi; Zhong, Jixin; Rajagopalan, Sanjay

Toxicological sciences. 2019 May 01; 169(1):95-107