Marc E. Gillespie, PhD

Adjunct Professor, Department of Biochemistry and Molecular Pharmacology

Keywords
Toxicology, Bioinformatics, Molecular Biology
Summary

Dr. Marc E. Gillespie received his doctorate in Oncological Sciences from the University of Utah in 1998 and is now is a Professor in the Department of Pharmaceutical Sciences at St. John’s University College of Pharmacy and Health Sciences. As Chair of the College Assessment Committee, he has been working and conducting research in assessment including the development of statistical approaches to assessment data analysis, accreditation, program development, and institutional core curriculum assessment. He leads and develops the College assessment program and regularly attending national accreditation and assessment meetings. As Chair of the Institutional Biosafety Committee, he provides institutional oversight of recombinant DNA research. Dr. Gillespie leads a research group focused on bioinformatics and biomarker discovery. Current projects range from the identification of chronic low-level lead exposure and manganese toxicity biomarkers to the mechanics of inflammatory inhibitor release. He teaches Pharmacogenomics, Public Health, Human Anatomy & Physiology and has experience from academia and industry to public health policy. He is currently an Editor/Curator for the Reactome Project, a pathway database of cellular level processes from "simple" events (biochemical reactions), to "complex" biological process (cell cycle). This project is a multinational effort to integrate the overwhelming proliferation of genomic data into a human readable and computationally tractable database. Dr. Gillespie has been learning, conducting, developing tools for and teaching science for more than twenty years and is active at all levels of science curriculum development.

Phone

718-990-6669

Academic office

8000 Utopia Parkway, St. Albert Hall

Queens, NY 11439

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Positions

Adjunct Professor, Department of Biochemistry and Molecular Pharmacology at NYU Grossman School of Medicine

Graduate Education

PhD from University of Utah

Postdoctoral Training

Sloan Kettering Institute, Rothman Laboratory

Pathway-based, reaction-specific annotation of disease variants for elucidation of molecular phenotypes

Orlic-Milacic, Marija; Rothfels, Karen; Matthews, Lisa; Wright, Adam; Jassal, Bijay; Shamovsky, Veronica; Trinh, Quang; Gillespie, Marc E; Sevilla, Cristoffer; Tiwari, Krishna; Ragueneau, Eliot; Gong, Chuqiao; Stephan, Ralf; May, Bruce; Haw, Robin; Weiser, Joel; Beavers, Deidre; Conley, Patrick; Hermjakob, Henning; Stein, Lincoln D; D'Eustachio, Peter; Wu, Guanming

Database : the journal of biological databases & curation. 2024 May 07; 2024:

The Reactome Pathway Knowledgebase 2024

Milacic, Marija; Beavers, Deidre; Conley, Patrick; Gong, Chuqiao; Gillespie, Marc; Griss, Johannes; Haw, Robin; Jassal, Bijay; Matthews, Lisa; May, Bruce; Petryszak, Robert; Ragueneau, Eliot; Rothfels, Karen; Sevilla, Cristoffer; Shamovsky, Veronica; Stephan, Ralf; Tiwari, Krishna; Varusai, Thawfeek; Weiser, Joel; Wright, Adam; Wu, Guanming; Stein, Lincoln; Hermjakob, Henning; D'Eustachio, Peter

Nucleic acids research. 2024 Jan 05; 52(D1):D672-D678

Using the Reactome Database

Rothfels, Karen; Milacic, Marija; Matthews, Lisa; Haw, Robin; Sevilla, Cristoffer; Gillespie, Marc; Stephan, Ralf; Gong, Chuqiao; Ragueneau, Eliot; May, Bruce; Shamovsky, Veronica; Wright, Adam; Weiser, Joel; Beavers, Deidre; Conley, Patrick; Tiwari, Krishna; Jassal, Bijay; Griss, Johannes; Senff-Ribeiro, Andrea; Brunson, Timothy; Petryszak, Robert; Hermjakob, Henning; D'Eustachio, Peter; Wu, Guanming; Stein, Lincoln

Current protocols. 2023 Apr; 3(4):e722

Drug-target identification in COVID-19 disease mechanisms using computational systems biology approaches

Niarakis, Anna; Ostaszewski, Marek; Mazein, Alexander; Kuperstein, Inna; Kutmon, Martina; Gillespie, Marc E; Funahashi, Akira; Acencio, Marcio Luis; Hemedan, Ahmed; Aichem, Michael; Klein, Karsten; Czauderna, Tobias; Burtscher, Felicia; Yamada, Takahiro G; Hiki, Yusuke; Hiroi, Noriko F; Hu, Finterly; Pham, Nhung; Ehrhart, Friederike; Willighagen, Egon L; Valdeolivas, Alberto; Dugourd, Aurelien; Messina, Francesco; Esteban-Medina, Marina; Peña-Chilet, Maria; Rian, Kinza; Soliman, Sylvain; Aghamiri, Sara Sadat; Puniya, Bhanwar Lal; Naldi, Aurélien; Helikar, Tomáš; Singh, Vidisha; Fernández, Marco Fariñas; Bermudez, Viviam; Tsirvouli, Eirini; Montagud, Arnau; Noël, Vincent; Ponce-de-Leon, Miguel; Maier, Dieter; Bauch, Angela; Gyori, Benjamin M; Bachman, John A; Luna, Augustin; Piñero, Janet; Furlong, Laura I; Balaur, Irina; Rougny, Adrien; Jarosz, Yohan; Overall, Rupert W; Phair, Robert; Perfetto, Livia; Matthews, Lisa; Rex, Devasahayam Arokia Balaya; Orlic-Milacic, Marija; Gomez, Luis Cristobal Monraz; De Meulder, Bertrand; Ravel, Jean Marie; Jassal, Bijay; Satagopam, Venkata; Wu, Guanming; Golebiewski, Martin; Gawron, Piotr; Calzone, Laurence; Beckmann, Jacques S; Evelo, Chris T; D'Eustachio, Peter; Schreiber, Falk; Saez-Rodriguez, Julio; Dopazo, Joaquin; Kuiper, Martin; Valencia, Alfonso; Wolkenhauer, Olaf; Kitano, Hiroaki; Barillot, Emmanuel; Auffray, Charles; Balling, Rudi; Schneider, Reinhard; ,

Frontiers in immunology. 2023 Feb; 14:1282859

The reactome pathway knowledgebase 2022

Gillespie, Marc; Jassal, Bijay; Stephan, Ralf; Milacic, Marija; Rothfels, Karen; Senff-Ribeiro, Andrea; Griss, Johannes; Sevilla, Cristoffer; Matthews, Lisa; Gong, Chuqiao; Deng, Chuan; Varusai, Thawfeek; Ragueneau, Eliot; Haider, Yusra; May, Bruce; Shamovsky, Veronica; Weiser, Joel; Brunson, Timothy; Sanati, Nasim; Beckman, Liam; Shao, Xiang; Fabregat, Antonio; Sidiropoulos, Konstantinos; Murillo, Julieth; Viteri, Guilherme; Cook, Justin; Shorser, Solomon; Bader, Gary; Demir, Emek; Sander, Chris; Haw, Robin; Wu, Guanming; Stein, Lincoln; Hermjakob, Henning; D'Eustachio, Peter

Nucleic acids research. 2022 Jan 07; 50(D1):D687-D692

COVID19 Disease Map, a computational knowledge repository of virus-host interaction mechanisms

Ostaszewski, Marek; Niarakis, Anna; Mazein, Alexander; Kuperstein, Inna; Phair, Robert; Orta-Resendiz, Aurelio; Singh, Vidisha; Aghamiri, Sara Sadat; Acencio, Marcio Luis; Glaab, Enrico; Ruepp, Andreas; Fobo, Gisela; Montrone, Corinna; Brauner, Barbara; Frishman, Goar; Monraz Gómez, Luis Cristóbal; Somers, Julia; Hoch, Matti; Kumar Gupta, Shailendra; Scheel, Julia; Borlinghaus, Hanna; Czauderna, Tobias; Schreiber, Falk; Montagud, Arnau; Ponce de Leon, Miguel; Funahashi, Akira; Hiki, Yusuke; Hiroi, Noriko; Yamada, Takahiro G; Dräger, Andreas; Renz, Alina; Naveez, Muhammad; Bocskei, Zsolt; Messina, Francesco; Börnigen, Daniela; Fergusson, Liam; Conti, Marta; Rameil, Marius; Nakonecnij, Vanessa; Vanhoefer, Jakob; Schmiester, Leonard; Wang, Muying; Ackerman, Emily E; Shoemaker, Jason E; Zucker, Jeremy; Oxford, Kristie; Teuton, Jeremy; Kocakaya, Ebru; Summak, Gökçe YaÄŸmur; Hanspers, Kristina; Kutmon, Martina; Coort, Susan; Eijssen, Lars; Ehrhart, Friederike; Rex, Devasahayam Arokia Balaya; Slenter, Denise; Martens, Marvin; Pham, Nhung; Haw, Robin; Jassal, Bijay; Matthews, Lisa; Orlic-Milacic, Marija; Senff Ribeiro, Andrea; Rothfels, Karen; Shamovsky, Veronica; Stephan, Ralf; Sevilla, Cristoffer; Varusai, Thawfeek; Ravel, Jean-Marie; Fraser, Rupsha; Ortseifen, Vera; Marchesi, Silvia; Gawron, Piotr; Smula, Ewa; Heirendt, Laurent; Satagopam, Venkata; Wu, Guanming; Riutta, Anders; Golebiewski, Martin; Owen, Stuart; Goble, Carole; Hu, Xiaoming; Overall, Rupert W; Maier, Dieter; Bauch, Angela; Gyori, Benjamin M; Bachman, John A; Vega, Carlos; Grouès, Valentin; Vazquez, Miguel; Porras, Pablo; Licata, Luana; Iannuccelli, Marta; Sacco, Francesca; Nesterova, Anastasia; Yuryev, Anton; de Waard, Anita; Turei, Denes; Luna, Augustin; Babur, Ozgun; Soliman, Sylvain; Valdeolivas, Alberto; Esteban-Medina, Marina; Peña-Chilet, Maria; Rian, Kinza; Helikar, Tomáš; Puniya, Bhanwar Lal; Modos, Dezso; Treveil, Agatha; Olbei, Marton; De Meulder, Bertrand; Ballereau, Stephane; Dugourd, Aurélien; Naldi, Aurélien; Noël, Vincent; Calzone, Laurence; Sander, Chris; Demir, Emek; Korcsmaros, Tamas; Freeman, Tom C; Augé, Franck; Beckmann, Jacques S; Hasenauer, Jan; Wolkenhauer, Olaf; Wilighagen, Egon L; Pico, Alexander R; Evelo, Chris T; Gillespie, Marc E; Stein, Lincoln D; Hermjakob, Henning; D'Eustachio, Peter; Saez-Rodriguez, Julio; Dopazo, Joaquin; Valencia, Alfonso; Kitano, Hiroaki; Barillot, Emmanuel; Auffray, Charles; Balling, Rudi; Schneider, Reinhard

Molecular systems biology. 2021 10; 17(10):e10387

Author Correction: COVID-19 Disease Map, building a computational repository of SARS-CoV-2 virus-host interaction mechanisms

Ostaszewski, Marek; Mazein, Alexander; Gillespie, Marc E; Kuperstein, Inna; Niarakis, Anna; Hermjakob, Henning; Pico, Alexander R; Willighagen, Egon L; Evelo, Chris T; Hasenauer, Jan; Schreiber, Falk; Dräger, Andreas; Demir, Emek; Wolkenhauer, Olaf; Furlong, Laura I; Barillot, Emmanuel; Dopazo, Joaquin; Orta-Resendiz, Aurelio; Messina, Francesco; Valencia, Alfonso; Funahashi, Akira; Kitano, Hiroaki; Auffray, Charles; Balling, Rudi; Schneider, Reinhard

Scientific data. 2020 07 17; 7(1):247

Using Reactome to build an autophagy mechanism knowledgebase

Varusai, Thawfeek Mohamed; Jupe, Steven; Sevilla, Cristoffer; Matthews, Lisa; Gillespie, Marc; Stein, Lincoln; Wu, Guanming; D'Eustachio, Peter; Metzakopian, Emmanouil; Hermjakob, Henning

Autophagy. 2020 Jun 02; 1-12

See All Publications (30)