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Margaret E. Rice

Margaret E. Rice, PhD

Professor, Department of Neurosurgery

Professor, Department of Neuroscience and Physiology

neurochemistry and neurophysiology of the nigrostriatal dopamine pathway; diet, insulin and leptin; molecular, cellular, and translational science; somatodendritic dopamine release and uptake, and whole-cell recording

Dr. Rice's NIH-funded laboratory studies factors that regulate the release of dopamine, which is a key transmitter in motor and reward pathways of the brain. Current topics include modulation of dopamine release in the striatum by diet and by the metabolic hormones insulin and leptin, the influence of exercise on dopamine levels and release, and how a Parkinson's-related protein, alpha-synuclein, affects the physiology of dopamine neurons in the substantia nigra. Methods used include fast-scan cyclic voltammetry, optogenetics, patch-clamp recording of basal ganglia neurons, and immunohistochemistry. Dr. Rice is an investigator in the Neuroscience Institute and a member of the Marlene and Paolo Fresco Institute for Parkinson’s and Movement Disorders at NYU Langone, and she serves on the Scientific Advisory Board of the Parkinson’s Foundation.



Academic office

455 First Avenue

Eighth Floor, Suite 869

New York, NY 10016

Lab Website
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These focus areas and their associated publications are derived from medical subject headings from PubMed.
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PhD from University of Kansas

Fellowship, New York University School of Medicine, Physiology and Biophysics

Patel, Jyoti C; Stouffer, Melissa A; Mancini, Maria; Nicholson, Charles; Carr, Kenneth D; Rice, Margaret E

European journal of neuroscience. 2019 Mar; 49(6):794-804

Stouffer, Melissa A; Woods, Catherine A; Patel, Jyoti C; Lee, Christian R; Witkovsky, Paul; Bao, Li; Machold, Robert P; Jones, Kymry T; de Vaca, Soledad Cabeza; Reith, Maarten E A; Carr, Kenneth D; Rice, Margaret E

Nature communications. 2015 Oct 27; 6:8543

Sulzer, David; Cragg, Stephanie J; Rice, Margaret E

Basal ganglia. 2016 Aug; 6(3):123-148

Jamalzadeh, Moeid; Cuniberto, Edoardo; Huang, Zhujun; Feeley, Ryan M; Patel, Jyoti C; Rice, Margaret E; Uichanco, Joline; Shahrjerdi, Davood

Analyst. 2024 Apr 15; 149(8):2351-2362

Patel, Jyoti C; Sherpa, Ang D; Melani, Riccardo; Witkovsky, Paul; Wiseman, Madeline R; O'Neill, Brian; Aoki, Chiye; Tritsch, Nicolas X; Rice, Margaret E

Cell reports. 2024 Mar 26; 43(3):113834

Patel, Jyoti C; Carr, Kenneth D; Rice, Margaret E

Biomolecules. 2023 Mar 11; 13(3):