Margaret E. Rice

Margaret E. Rice, PhD

Professor, Department of Neurosurgery

Professor, Department of Neuroscience and Physiology

Keywords
neurochemistry and neurophysiology of the nigrostriatal dopamine pathway, diet, insulin, leptin, molecular, cellular, & translational neuroscience, somatodendritic dopamine release, dopamine release and uptake, whole-cell recording
Summary

Dr. Rice's NIH-funded laboratory studies factors that regulate the release of dopamine, which is a key transmitter in motor and reward pathways of the brain. Current topics include modulation of dopamine release in the striatum by diet and by the metabolic hormones insulin and leptin, the influence of exercise on dopamine levels and release, and how a Parkinson's-related protein, alpha-synuclein, affects the physiology of dopamine neurons in the substantia nigra. Methods used include fast-scan cyclic voltammetry, optogenetics, patch-clamp recording of basal ganglia neurons, and immunohistochemistry. Dr. Rice is an Investigator in the Neuroscience Institute, a member of the Marlene and Paolo Fresco Institute on Parkinson’s disease and Movement Disorders at NYU, and serves on the Scientific Advisory Board of the Parkinson’s Foundation.

Phone

212-263-5438

Academic office

455 First Avenue

Eighth Floor, Suite 869

New York, NY 10016

Lab Website
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Professor, Department of Neurosurgery

Professor, Department of Neuroscience and Physiology

PhD from University of Kansas

Fellowship, New York University School of Medicine, Physiology and Biophysics

Rice, Margaret E

ACS chemical neuroscience. 2017 Feb 7; 8(2):215-217

Farooq, Mobeen; Kim, Seonil; Patel, Sunny; Khatri, Latika; Hikima, Takuya; Rice, Margaret E; Ziff, Edward B

Neuropharmacology. 2017 Feb; 113(Pt A):426-433

Sulzer, D; Cragg, SJ; Rice, ME

Handbook of behavioral neuroscience. 2017; 24:373-402

Ludwig, Mike; Apps, David; Menzies, John; Patel, Jyoti C; Rice, Margaret E

Comprehensive physiology. 2016 Dec 06; 7(1):235-252

Asri, R; O'Neill, B; Patel, J C; Siletti, K A; Rice, M E

Analyst. 2016 Nov 14; 141(23):6416-6421

Sulzer, David; Cragg, Stephanie J; Rice, Margaret E

Basal ganglia. 2016 Aug; 6(3):123-148

Stouffer, Melissa A; Woods, Catherine A; Patel, Jyoti C; Lee, Christian R; Witkovsky, Paul; Bao, Li; Machold, Robert P; Jones, Kymry T; de Vaca, Soledad Cabeza; Reith, Maarten E A; Carr, Kenneth D; Rice, Margaret E

Nature communications. 2015 Oct 27; 6:8543-8543