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Mario Delmar, MD, PhD

Patricia M. and Robert H. Martinsen Professor of Cardiology, Department of Medicine

Professor, Department of Cell Biology

Arrhythmogenic right ventricular cardiomyopathy, channelopathies, sudden death in the young, cellular/molecular mechanisms of arrhythmias, gene therapy for arrhythmogenic cardiomyopathy

Debunking the concept of one gene-one disease in inheritable arrhythmia death; cellular/molecular mechanisms of arrhythmogenic right ventricular cardiomyopathy and its overlap with other inheritable arrhythmia syndromes.

Our laboratory studies the cellular and molecular mechanisms leading to sudden cardiac death in patients with inheritable arrhythmia syndromes; our primary focus is on arrhythmogenic right ventricular cardiomyopathy (ARVC) and its overlapping syndromes (Brugada syndrome and catecholaminergic polymorphic ventricular tachycardia). We seek to understand the causes of the arrhythmias; develop approaches toward their prevention and treatment; and identify factors that place individuals at risk of sudden death. Our experimental approaches are multidisciplinary and include super-resolution microscopy and other advanced imaging methods, scanning patch clamp, genetically modified animal models, and human induced pluripotent stem cell–derived cardiomyocytes.



Academic office

435 EAST 30TH St


New York, NY 10016

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These focus areas and their associated publications are derived from medical subject headings from PubMed.
represents one publication
*Due to PubMed processing times, the most recent publications may not be reflected in the timeline.

MD from National Autonomous University of Mexico

SUNY Upstate Medical University. Syracuse NY, Cardiac electrophysiology

van Opbergen, Chantal J M; Narayanan, Bitha; B Sacramento, Chester; Stiles, Katie M; Mishra, Vartika; Frenk, Esther; Ricks, David; Chen, Grace; Zhang, Mingliang; Yarabe, Paul; Schwartz, Jonathan; Delmar, Mario; Herzog, Chris D; Cerrone, Marina

Circulation. Genomic & precision medicine. 2024 Jan 30; e004305

Maurya, Svetlana; Mills, Robert W.; Kahnert, Konstantin; Chiang, David Y.; Bertoli, Giorgia; Lundegaard, Pia R.; Duran, Marta Perez Hernandez; Zhang, Mingliang; Rothenberg, Eli; George, Alfred L.; MacRae, Calum A.; Delmar, Mario; Lundby, Alicia

Nature cardiovascular research. 2023 Jul 01; 2(<prism:issueIdentifier>7):673-692

Leybaert, Luc; De Smet, Maarten Aj; Lissoni, Alessio; Allewaert, Rosalie; Roderick, H Llewelyn; Bultynck, Geert; Delmar, Mario; Sipido, Karin R; Witschas, Katja

Journal of clinical investigation. 2023 Mar 15; 133(6):

Liang, Feng-Xia; Sall, Joseph; Petzold, Chris; van Opbergen, Chantal J M; Liang, Xiangxi; Delmar, Mario

Methods in cell biology. 2023 Jul; 177:55-81

Cerrone, Marina; Costa, Sarah; Delmar, Mario

Annual review of genomics & human genetics. 2022 Aug 31; 23:255-274

Pérez-Hernández, Marta; van Opbergen, Chantal J M; Bagwan, Navratan; Rasmus Vissing, Christoffer; Marrón-Liñares, Grecia M; Zhang, Mingliang; Torres Vega, Estefania; Sorrentino, Andrea; Drici, Lylia; Sulek, Karolina; Zhai, Ruxu; Hansen, Finn B; Hørby Christensen, Alex; Boesgaard, Søren; Gustafsson, Finn; Rossing, Kasper; Small, Eric M; Davies, Michael J; Rothenberg, Eli; Sato, Priscila; Cerrone, Marina; Jensen, Thomas Hartvig Lindkær; Qvortrup, Klaus; Bundgaard, Henning; Delmar, Mario; Lundby, Alicia

Circulation. 2022 Aug 12; 101161CIRCULATIONAHA12206

Yang, Hua-Qian; Echeverry, Fabio A; ElSheikh, Assmaa; Gando, Ivan; Anez Arredondo, Sophia; Samper, Natalie; Cardozo, Timothy; Delmar, Mario; Shyng, Show-Ling; Coetzee, William A

American journal of physiology. Cell physiology. 2022 Jun 01; 322(6):C1230-C1247

van Opbergen, Chantal J M; Bagwan, Navratan; Maurya, Svetlana R; Kim, Joon-Chul; Smith, Abigail N; Blackwell, Daniel J; Johnston, Jeffrey N; Knollmann, Björn C; Cerrone, Marina; Lundby, Alicia; Delmar, Mario

Circulation. 2022 May 10; 145(19):1480-1496