Mark A. Bernard, PhD

I am a Research Assistant Professor in the Department of Neurology, where I am part of the Alzheimer’s Disease Research Center (ADRC) and its Biomarker Core.  My current research is focused on understanding the role of biomarkers of Alzheimer’s Disease (AD) in disease pathogenesis, with specific focus on those in blood plasma.  I am investigating associations between neuropsychiatric symptoms (such as anxiety and depression) and changes in these biomarkers, and am further interested in the nexus between these biomarkers and sleep and circadian rhythm dysfunctions.

I am a chemical biologist by training, with a PhD in Organic Chemistry, and I have postdoctoral training and a Master’s degree in Clinical Epidemiology and Health Services Research.  This unique background, combining basic physical sciences and clinical research, informs my  continued interest not only in elucidating molecular mechanisms of disease progression and developing novel therapeutics, but also in developing culturally-competent methods of translational research, aimed at reducing health disparities in underserved communities.

Moving forward, I intend to continue research efforts encompassing these diverse interests, incorporating basic science, understanding of mechanisms of disease, and study of the clinical outcomes. Mentoring and teaching future generations is also very important to me, so I look forward to those opportunities as well.  Another area of great importance to me is diversity, equity, and inclusion. Representation of people of all backgrounds in the sciences is vitally important if science is to truly serve all mankind.