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Mary Cowman

Mary Cowman, PhD

Professor, Department of Orthopedic Surgery

Keywords
hyaluronan, glycosaminoglycans, extracellular matrix, cartilage, biotherapeutics, diagnostics, biomaterials
Summary

Our laboratory focuses on the structure, function, and medical applications of the biomatrix surrounding cells, with special expertise in the glycosaminoglycan hyaluronan.

We use both bioanalytical and biophysical approaches to identify biomarkers and bioactive fragments derived from the extracellular matrix, and to develop medical diagnostic assays. We apply our knowledge to discover and develop biotherapeutics and biomaterials.

Phone

212-992-5971

Fax

212-995-4009

Academic office

433 First Avenue

Room 910

New York, NY 10010

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These focus areas and their associated publications are derived from medical subject headings from PubMed.
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Positions

Professor, Department of Orthopedic Surgery at NYU Grossman School of Medicine

Graduate Education

PhD from Case Western Reserve University

Postdoctoral Training

Brandeis University, Biochemistry

Columbia University College of Physicians and Surgeons, Ophthalmology

Selective isolation of hyaluronan by solid phase adsorption to silica

MacLeod, Rebecca; Chan, Fok Vun; Yuan, Han; Ye, Xin; Sin, Yun Jin Ashley; Vitelli, Teraesa M; Cucu, Tudor; Leung, Annie; Baljak, Irene; Osinski, Samantha; Fu, Yuhong; Jung, Gyu Ik Daniel; Amar, Anant; DeAngelis, Paul L; Hellman, Urban; Cowman, Mary K

Analytical biochemistry. 2022 Sep 01; 652:114769

Densification: Hyaluronan Aggregation in Different Human Organs

Stecco, Antonio; Cowman, Mary; Pirri, Nina; Raghavan, Preeti; Pirri, Carmelo

Bioengineering. 2022 Apr 05; 9(4):

Methods for Isolating and Analyzing Physiological Hyaluronan: A Review

Rivas, Felipe; Erxleben, Dorothea; Smith, Ian; Rahbar, Elaheh; DeAngelis, Paul J; Cowman, Mary K; Hall, Adam R

American journal of physiology. Cell physiology. 2022 Apr 01; 322(4):C674-C687

In vivo multimodal imaging of hyaluronan-mediated inflammatory response in articular cartilage

Ruiz, Amparo; Duarte, Alejandra; Bravo, Dalibel; Ramos, Elisa; Zhang, Chongda; Cowman, Mary K; Kirsch, Thorsten; Milne, Mark; Luyt, Leonard G; Raya, José G

Osteoarthritis & cartilage. 2022 Feb; 30(2):329-340

Noncovalent hyaluronan crosslinking by TSG-6: Modulation by heparin, heparan sulfate, and PRG4

Sin, Yun Jin Ashley; MacLeod, Rebecca; Tanguay, Adam P; Wang, Andrew; Braender-Carr, Olivia; Vitelli, Teraesa M; Jay, Gregory D; Schmidt, Tannin A; Cowman, Mary K

Frontiers in molecular biosciences. 2022 Oct; 9:990861

MTADV 5-MER peptide suppresses chronic inflammations as well as autoimmune pathologies and unveils a new potential target-Serum Amyloid A

Hemed-Shaked, Maayan; Cowman, Mary K; Kim, Jin Ryoun; Huang, Xiayun; Chau, Edward; Ovadia, Haim; Amar, Keren-Or; Eshkar-Sebban, Lora; Melamed, Michal; Lev, Libat Bar; Kedar, Eli; Armengol, Jordi; Alemany, Jorge; Beyth, Shaul; Okon, Eli; Kanduc, Darja; Elgavish, Sharona; Wallach-Dayan, Shulamit B; Cohen, Shmuel Jaffe; Naor, David

Journal of autoimmunity. 2021 Aug 12; 124:102713

Protective Effects of a Hyaluronan-Binding Peptide (P15-1) on Mesenchymal Stem Cells in an Inflammatory Environment

Kirsch, Thorsten; Zhang, Fenglin; Braender-Carr, Olivia; Cowman, Mary K

International journal of molecular sciences. 2021 Jun 30; 22(13):

Extracellular vesicles released from articular chondrocytes play a major role in cell-cell communication

Liu, Xiaoming; Shortt, Claire; Zhang, Fenglin; Bater, Mariah Q; Cowman, Mary K; Kirsch, Thorsten

Journal of orthopaedic research. 2020 Apr; 38(4):731-739

See All Publications (117)