Mary Cowman

Mary Cowman, PhD

Professor, Department of Orthopedic Surgery

Keywords
hyaluronan, glycosaminoglycans, extracellular matrix, cartilage, biotherapeutics, diagnostics, biomaterials
Summary

Our laboratory focuses on the structure, function, and medical applications of the biomatrix surrounding cells, with special expertise in the glycosaminoglycan hyaluronan.

We use both bioanalytical and biophysical approaches to identify biomarkers and bioactive fragments derived from the extracellular matrix, and to develop medical diagnostic assays. We apply our knowledge to discover and develop biotherapeutics and biomaterials.

Phone

212-992-5971

Fax

212-995-4009

Academic office

433 First Avenue

Room 910

New York, NY 10010

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Positions

Professor, Department of Orthopedic Surgery at NYU Grossman School of Medicine

Graduate Education

PhD from Case Western Reserve University

Postdoctoral Training

Brandeis University, Biochemistry

Columbia University College of Physicians and Surgeons, Ophthalmology

Targeting mitochondria in Cancer therapy: Machine learning analysis of hyaluronic acid-based drug delivery systems

Iaconisi, Giorgia Natalia; Ahmed, Amer; Lauria, Graziantonio; Gallo, Nunzia; Fiermonte, Giuseppe; Cowman, Mary K; Capobianco, Loredana; Dolce, Vincenza

International journal of biological macromolecules. 2024 Nov 19; 283(Pt 4):137840

The Role of Hyaluronan/Receptor for Hyaluronan-Mediated Motility Interactions in the Modulation of Macrophage Polarization and Cartilage Repair

Bianchini, Emilia; Ashley Sin, Yun Jin; Lee, You Jin; Lin, Charles; Anil, Utkarsh; Hamill, Cassie; Cowman, Mary K; Kirsch, Thorsten

American journal of pathology. 2024 Jun; 194(6):1047-1061

The spatial separation of basic amino acids is similar in RHAMM and hyaluronan binding peptide P15-1 despite different sequences and conformations

Erkanli, Mehmet Emre; Kang, Ted Keunsil; Kirsch, Thorsten; Turley, Eva A; Kim, Jin Ryoun; Cowman, Mary K

Proteoglycan research. 2024 Oct; 2(3):e70001

Selective isolation of hyaluronan by solid phase adsorption to silica

MacLeod, Rebecca; Chan, Fok Vun; Yuan, Han; Ye, Xin; Sin, Yun Jin Ashley; Vitelli, Teraesa M; Cucu, Tudor; Leung, Annie; Baljak, Irene; Osinski, Samantha; Fu, Yuhong; Jung, Gyu Ik Daniel; Amar, Anant; DeAngelis, Paul L; Hellman, Urban; Cowman, Mary K

Analytical biochemistry. 2022 Sep 01; 652:114769

Densification: Hyaluronan Aggregation in Different Human Organs

Stecco, Antonio; Cowman, Mary; Pirri, Nina; Raghavan, Preeti; Pirri, Carmelo

Bioengineering. 2022 Apr 05; 9(4):

Methods for Isolating and Analyzing Physiological Hyaluronan: A Review

Rivas, Felipe; Erxleben, Dorothea; Smith, Ian; Rahbar, Elaheh; DeAngelis, Paul J; Cowman, Mary K; Hall, Adam R

American journal of physiology. Cell physiology. 2022 Apr 01; 322(4):C674-C687

In vivo multimodal imaging of hyaluronan-mediated inflammatory response in articular cartilage

Ruiz, Amparo; Duarte, Alejandra; Bravo, Dalibel; Ramos, Elisa; Zhang, Chongda; Cowman, Mary K; Kirsch, Thorsten; Milne, Mark; Luyt, Leonard G; Raya, José G

Osteoarthritis & cartilage. 2022 Feb; 30(2):329-340

Noncovalent hyaluronan crosslinking by TSG-6: Modulation by heparin, heparan sulfate, and PRG4

Sin, Yun Jin Ashley; MacLeod, Rebecca; Tanguay, Adam P; Wang, Andrew; Braender-Carr, Olivia; Vitelli, Teraesa M; Jay, Gregory D; Schmidt, Tannin A; Cowman, Mary K

Frontiers in molecular biosciences. 2022 Oct; 9:990861

See All Publications (121)