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Meike Dittmann

Meike Dittmann, PhD

Associate Professor, Department of Microbiology

virology, innate immunity, high-content imaging, respiratory viruses, influenza virus

In our lab we investigate how the human respiratory system battles viral infections. Lower respiratory tract infections are a leading cause of death in the United States and the leading infectious cause of death worldwide, claiming 3.1 million lives each year. Our hope is that a better understanding of the body’s own protection strategies will enable us to develop novel antiviral therapies.

Our main expertise lies in high-content imaging, which we use to monitor subcellular immune system events that occur in response to viral infection. We are particularly interested in events that are triggered by interferons—proteins that act as potent innate immune messengers.

In the first hours of infection, infected cells produce interferons, which alert neighboring cells to immediately activate specific cellular genes, known as interferon-stimulated genes (ISGs). There are several hundred different ISGs that together are a strong force against viruses. However, we know little about what the individual ISGs do.

We study the role of individual ISGs, their antiviral mechanisms, and their contribution to keeping respiratory viruses in check. We are currently working on three main projects:

  • identify and characterize ISGs that inhibit respiratory viruses
  • characterize the role of serpins during virus life cycles
  • develop human model systems for studying respiratory viruses


Academic office

430 East 29th Street

3rd floor, Room 313

New York, NY 10016

Lab Website
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These focus areas and their associated publications are derived from medical subject headings from PubMed.
represents one publication
*Due to PubMed processing times, the most recent publications may not be reflected in the timeline.

Fellowship, NIH/NIAID, K99/R00 Pathway to Independence

Fellowship, The Rockefeller University, Women & Science Postdoctoral Fellowship

Fellowship, The Rockefeller University, Pilot project grant - Center for Clinical and Translational Science and Helmsley Charitable Trust/Center on Disorders of the Digestive System

Fellowship, Deutsche Forschungsgemeinschaft (German Research Foundation), Postdoctoral Fellowship

Dittmann, Meike; Hoffmann, Hans-Heinrich; Scull, Margaret A; Gilmore, Rachel H; Bell, Kierstin L; Ciancanelli, Michael; Wilson, Sam J; Crotta, Stefania; Yu, Yingpu; Flatley, Brenna; Xiao, Jing W; Casanova, Jean-Laurent; Wack, Andreas; Bieniasz, Paul D; Rice, Charles M

Cell. 2015 Feb 12; 160(4):631-643

Yao, Hui; Dittmann, Meike; Peisley, Alys; Hoffmann, Hans-Heinrich; Gilmore, Rachel H; Schmidt, Tobias; Schmid-Burgk, Jonathan L; Hornung, Veit; Rice, Charles M; Hur, Sun

Molecular cell. 2015 May 07; 58(3):541-548

de Vries, Maren; Ciabattoni, Grace O; Rodriguez-Rodriguez, Bruno A; Crosse, Keaton M; Papandrea, Dominick; Samanovic, Marie I; Dimartino, Dacia; Marier, Christian; Mulligan, Mark J; Heguy, Adriana; Desvignes, Ludovic; Duerr, Ralf; Dittmann, Meike

Nature protocols. 2023 Dec; 18(12):3821-3855

Prescott, Rachel A; Pankow, Alec P; de Vries, Maren; Crosse, Keaton M; Patel, Roosheel S; Alu, Mark; Loomis, Cynthia; Torres, Victor; Koralov, Sergei; Ivanova, Ellie; Dittmann, Meike; Rosenberg, Brad R

Respiratory research. 2023 Aug 28; 24(1):213

Rodriguez-Rodriguez, Bruno A; Ciabattoni, Grace O; Duerr, Ralf; Valero-Jimenez, Ana M; Yeung, Stephen T; Crosse, Keaton M; Schinlever, Austin R; Bernard-Raichon, Lucie; Rodriguez Galvan, Joaquin; McGrath, Marisa E; Vashee, Sanjay; Xue, Yong; Loomis, Cynthia A; Khanna, Kamal M; Cadwell, Ken; Desvignes, Ludovic; Frieman, Matthew B; Ortigoza, Mila B; Dittmann, Meike

Nature communications. 2023 May 25; 14(1):3026

Rodriguez-Rodriguez, Bruno A; Ciabattoni, Grace O; Valero-Jimenez, Ana M; Crosse, Keaton M; Schinlever, Austin R; Galvan, Joaquin J Rodriguez; Duerr, Ralf; Yeung, Stephen T; McGrath, Marisa E; Loomis, Cynthia; Khanna, Kamal M; Desvignes, Ludovic; Frieman, Matthew F; Ortigoza, Mila B; Dittmann, Meike : the preprint server for biology. 2023 Mar 24;

Duerr, Ralf; Zhou, Hao; Tada, Takuya; Dimartino, Dacia; Marier, Christian; Zappile, Paul; Wang, Guiqing; Plitnick, Jonathan; Griesemer, Sara B.; Girardin, Roxanne; Machowski, Jessica; Bialosuknia, Sean; Lasek-Nesselquist, Erica; Hong, Samuel L.; Baele, Guy; Dittmann, Meike; Ortigoza, Mila B.; Prasad, Prithiv J.; McDonough, Kathleen; Landau, Nathaniel R.; St George, Kirsten; Heguy, Adriana

iScience. 2023 Feb 17; 26(<prism:issueIdentifier>2):?-?

Bernard-Raichon, Lucie; Venzon, Mericien; Klein, Jon; Axelrad, Jordan E; Zhang, Chenzhen; Sullivan, Alexis P; Hussey, Grant A; Casanovas-Massana, Arnau; Noval, Maria G; Valero-Jimenez, Ana M; Gago, Juan; Putzel, Gregory; Pironti, Alejandro; Wilder, Evan; Thorpe, Lorna E; Littman, Dan R; Dittmann, Meike; Stapleford, Kenneth A; Shopsin, Bo; Torres, Victor J; Ko, Albert I; Iwasaki, Akiko; Cadwell, Ken; Schluter, Jonas

Nature communications. 2022 Nov 01; 13(1):5926