Melissa J. Alldred, PhD

Research Assistant Professor, Department of Psychiatry

Positions

Research Assistant Professor, Department of Psychiatry at NYU Grossman School of Medicine

Graduate Education

PhD from Penn State University

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Down syndrome frontal cortex layer III and layer V pyramidal neurons exhibit lamina specific degeneration in aged individuals

Alldred, Melissa J; Ibrahim, Kyrillos W; Pidikiti, Harshitha; Chiosis, Gabriela; Mufson, Elliott J; Stutzmann, Grace E; Ginsberg, Stephen D

Acta neuropathologica communications. 2024 Nov 27; 12(1):182

Analysis of microisolated frontal cortex excitatory layer III and V pyramidal neurons reveals a neurodegenerative phenotype in individuals with Down syndrome

Alldred, Melissa J; Pidikiti, Harshitha; Ibrahim, Kyrillos W; Lee, Sang Han; Heguy, Adriana; Hoffman, Gabriel E; Roussos, Panos; Wisniewski, Thomas; Wegiel, Jerzy; Stutzmann, Grace E; Mufson, Elliott J; Ginsberg, Stephen D

Acta neuropathologica. 2024 Aug 06; 148(1):16

Early-life prefrontal cortex inhibition and early-life stress lead to long-lasting behavioral, transcriptional, and physiological impairments

Menezes, Edênia C; Geiger, Heather; Abreu, Fabiula F; Rachmany, Lital; Wilson, Donald A; Alldred, Melissa J; Castellanos, Francisco X; Fu, Rui; Sargin, Derya; Corvelo, André; Teixeira, Cátia M

Molecular psychiatry. 2024 Aug; 29(8):2359-2371

Synthesis and Characterization of Click Chemical Probes for Single-Cell Resolution Detection of Epichaperomes in Neurodegenerative Disorders

Bay, Sadik; Digwal, Chander S; Rodilla Martín, Ananda M; Sharma, Sahil; Stanisavljevic, Aleksandra; Rodina, Anna; Attaran, Anoosha; Roychowdhury, Tanaya; Parikh, Kamya; Toth, Eugene; Panchal, Palak; Rosiek, Eric; Pasala, Chiranjeevi; Arancio, Ottavio; Fraser, Paul E; Alldred, Melissa J; Prado, Marco A M; Ginsberg, Stephen D; Chiosis, Gabriela

Biomedicines. 2024 Jun 04; 12(6):

Apolipoprotein E2 Expression Alters Endosomal Pathways in a Mouse Model With Increased Brain Exosome Levels During Aging

Peng, Katherine Y; Liemisa, Braison; Pasato, Jonathan; D'Acunzo, Pasquale; Pawlik, Monika; Heguy, Adriana; Penikalapati, Sai C; Labuza, Amanda; Pidikiti, Harshitha; Alldred, Melissa J; Ginsberg, Stephen D; Levy, Efrat; Mathews, Paul M

Traffic. 2024 May; 25(5):e12937

Hippocampal CA1 Pyramidal Neurons Display Sublayer and Circuitry Dependent Degenerative Expression Profiles in Aged Female Down Syndrome Mice

Alldred, Melissa J; Pidikiti, Harshitha; Ibrahim, Kryillos W; Lee, Sang Han; Heguy, Adriana; Hoffman, Gabriel E; Mufson, Elliott J; Stutzmann, Grace E; Ginsberg, Stephen D

Journal of Alzheimer's disease. 2024 Sep; 100(s1):S341-S362

Maternal choline supplementation protects against age-associated cholinergic and GABAergic basal forebrain neuron degeneration in the Ts65Dn mouse model of Down syndrome and Alzheimer's disease

Gautier, Megan K; Kelley, Christy M; Lee, Sang Han; Alldred, Melissa J; McDaid, John; Mufson, Elliott J; Stutzmann, Grace E; Ginsberg, Stephen D

Neurobiology of disease. 2023 Nov; 188:106332

Basal forebrain cholinergic neurons are vulnerable in a mouse model of Down syndrome and their molecular fingerprint is rescued by maternal choline supplementation

Alldred, Melissa J; Pidikiti, Harshitha; Heguy, Adriana; Roussos, Panos; Ginsberg, Stephen D

FASEB journal. 2023 Jun; 37(6):e22944

See All Publications (78)